Biomedical subjects
Publications and source records attributed to Sultana Rajia.
Two triglycerides, both bearing polyunsaturated fatty acid residues, were isolated from the hexane extract of Urena lobata. One of them is characterized by the presence of three different polyunsaturated fatty acids. Their structures were studied with spectral methods.
From Sarcolobus globosus, two rotenoids (villosinol and 6-oxo-6a,12a-dehydrodeguelin), one isoflavone (genistin) and four phenolic glycosides (vanillic acid 4-O-beta-d-glucoside, glucosyringic acid, tachioside and isotachioside) were identified for the first time from this species. Extracts and compounds from S. globosus were evaluated for their DPPH radical scavenging and 15-lipoxygenase (15-LO) inhibitory activities. All tested rotenoids were found to inhibit 15-LO, while they lacked DPPH radical scavenging effect.
Sarcolobus globosus is a medicinal plant growing in mangrove forests in Asia. No constituents from this plant have been reported previously. From the diethyl ether extract of S. globosus a new rotenoid sarcolobin and a new isoflavone sarcolobone, as well as the previously known rotenoids tephrosin, 12aalpha-hydroxydeguelin, 11-hydroxytephrosin, 12a-hydroxyrotenone, 12aalpha-hydroxyrotenone, 6aalpha,12aalpha-12a-hydroxyelliptone, 6a,12a-dehydrodeguelin, 13- homo-13-oxa-6a,12a-dehydrodeguelin, the isoflavone barbigerone and a chromone 6,7-dimethoxy-2,3-dihydrochromone were identified. 6,7-Dimethoxy-2,3-dihydrochromone has not previously been reported as a natural product.