Biomedical subjects

Sung Bae Hwang

Publications and source records attributed to Sung Bae Hwang.

4 recordsLinked to original sources

PubMed2006

Method for preparing permanent brain slices and serial slice images for education and MRI correlation.

It is important to understand the anatomical structures of the human brain in horizontal planes. Serially sectioned brain slices can easily be made with a meat slicer. The objective of this research was to enhance the educational value of serial brain slices made with a meat slicer through various applications. Two brains were taken out of two cadavers and embedded with gelatin solution to make two brain blocks. The first brain block was serially sectioned at 5 mm thickness using a meat slicer to make 28 horizontal brain slices. Each brain slice was embedded with a synthetic resin mixture to make 28 permanent specimens. The second brain block was magnetic resonance-scanned at 1.4 mm thickness to make 130 horizontal magnetic resonance images, then serially sectioned at the same thickness using the meat slicer to make 130 horizontal brain slices. Each brain slice was scanned into a computer to make a series of slice images. Ten anatomical structures in the slice images were outlined to make segmented images. Corresponding magnetic resonance images, slice images, and segmented images were stacked and volume-reconstructed to make three-dimensional images, which were sectioned and rotated at free angles. We show that the serial brain slices made with a meat slicer can be permanently preserved and used in a variety of educational settings. Anat Rec (Part B: New Anat) 289B:64-71, 2006. (c) 2006 Wiley-Liss, Inc.

Brain↗

PubMed2006

Visible Korean Human: its techniques and applications.

Three recent studies have offered an unprecedented view of the human body. The Visible Human Project, the Visible Korean Human (VKH), and the Chinese Visible Human have featured the serial sectioning of whole cadavers, producing cross-sectional images that methodically catalogue gross human anatomy. By volumetric reconstruction, these cross-sectional images can be transformed into three-dimensional (3D) images of anatomic structures. Compiling these 3D images would create an invaluable library for medical education and research. The goal of this report is to promote the expansion of such a library of 3D anatomic images and to help users fully understand and utilize the serially sectioned images. To do this, we will discuss the fundamental techniques and equipment used in the VKH and its preliminary experiments. We will also address new applications of the VKH, including virtual brain surgery, virtual endoscopy, and virtual cardiopulmonary resuscitation via the development of virtual dissection software.

Anatomy↗

PubMed2005

Technical report on semiautomatic segmentation using the Adobe Photoshop.

The purpose of this research is to enable users to semiautomatically segment the anatomical structures in magnetic resonance images (MRIs), computerized tomographs (CTs), and other medical images on a personal computer. The segmented images are used for making 3D images, which are helpful to medical education and research. To achieve this purpose, the following trials were performed. The entire body of a volunteer was scanned to make 557 MRIs. On Adobe Photoshop, contours of 19 anatomical structures in the MRIs were semiautomatically drawn using MAGNETIC LASSO TOOL and manually corrected using either LASSO TOOL or DIRECT SELECTION TOOL to make 557 segmented images. In a similar manner, 13 anatomical structures in 8,590 anatomical images were segmented. Proper segmentation was verified by making 3D images from the segmented images. Semiautomatic segmentation using Adobe Photoshop is expected to be widely used for segmentation of anatomical structures in various medical images.

Anatomy, Cross-Sectional↗

PubMed2005

Visible Korean human: improved serially sectioned images of the entire body.

The data from the Visible Human Project (VHP) and the Chinese Visible Human (CVH), which are the serially sectioned images of the entire cadaver, are being used to produce three-dimensional (3-D) images and software. The purpose of our research, the Visible Korean Human (VKH), is to produce an enhanced version of the serially sectioned images of an entire cadaver that can be used to upgrade the 3-D images and software. These improvements are achieved without drastically changing the methods developed for the VHP and CVH; thus, a complementary solution was found. A Korean male cadaver was chosen without anything perfused into the cadaver; the entire body was magnetic resonance (MR) and computed tomography (CT) scanned at 1.0-mm intervals to produce MR and CT images. After scanning, entire body of the cadaver was embedded and serially sectioned at 0.2-mm intervals; each sectioned surface was inputted into a personal computer to produce anatomical images (pixel size: 0.2 mm) without any missing images. Eleven anatomical organs in the anatomical images were segmented to produce segmented images. The anatomical and segmented images were stacked and reconstructed to produce 3-D images. The VKH is an ongoing research; we will produce a female version of the VKH and provide more detailed segmented images. The data from the VHP, CVH, and VKH will provide valuable resources to the medical image library of 3-D images and software in the field of medical education and clinical trials.

Adult↗