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Biomedical subjects

Susan J Blalock

Publications and source records attributed to Susan J Blalock.

10 recordsLinked to original sources

Types of medication errors in North Carolina nursing homes: a target for quality improvement.

BACKGROUND: Medication errors are an important problem in nursing homes, but little is known about the types of medications involved in errors in this setting. Gaining a better understanding of the types of medications commonly involved in medication errors in nursing homes would be an important step toward quality improvement. OBJECTIVES: This study sought to describe the types of medication errors most frequently reported to a statewide repository by North Carolina nursing homes. We also examined whether nursing homes reporting an error involving a drug on the updated Beers list of medications considered potentially inappropriate for use in the elderly were likely to report a greater number of medication errors or more harmful medication errors compared with nursing homes that did not report such an error. METHODS: Medication errors were defined as preventable events that had the potential to cause/lead to or actually caused/led to inappropriate medication use or patient harm. We analyzed summary reports of medication errors submitted to the State of North Carolina by licensed nursing homes for the 9-month period from January 1, 2004, to September 30, 2004, using a Web-based reporting system. Drugs commonly involved in medication errors were summarized for all nursing homes in the state. Errors involving medications on the updated Beers list also were identified. Nursing homes were profiled and compared according to the type of medication error and whether the error reached the patient and/or caused harm. RESULTS: Among the 384 licensed nursing homes included in our analysis, 9272 medication errors were reported. The specific medication involved was documented for 5986 of these errors. The medications most commonly involved in an error were lorazepam (457 errors [8%]), warfarin (349 [6%]), insulin (332 [6%]), hydrocodone and hydrocodone combinations (233 [4%]), furosemide (173 [3%]), and the fentanyl patch (150 [3%]). The medication errors disproportionately included central nervous system agents (16%) and analgesics (11%). Medications considered potentially inappropriate in the elderly were frequently involved in the reported errors (10% of all reported errors), with the greatest number of such errors associated with lorazepam (457 [8%]), alprazolam (130 [2%]), and digoxin (74 [1%]). Nursing homes reporting potentially inappropriate drugs among their 10 most common medication errors also reported a significantly greater mean number of errors compared with nursing homes that did not report such errors (26.9 vs 17.6, respectively; P < 0.001), as well as a significantly greater number of errors that reached the patient (6148 vs 1393; P < 0.001). CONCLUSION: Based on the experience in North Carolina, quality improvement efforts in nursing homes should focus on the medications commonly involved in errors and should continue to discourage or closely monitor the use of medications considered potentially inappropriate in the elderly.

Adverse Drug Reaction Reporting Systems↗

Caregiver psychological distress as a barrier to influenza vaccination among community-dwelling elderly with dementia.

OBJECTIVE: This study examined whether informal caregiver psychologic distress decreases the likelihood of influenza vaccination for community-dwelling elderly with dementia. A secondary aim was to determine whether psychologic distress mediates the relationship between other predisposing, enabling, and medical need variables and vaccination. METHODS: Data were drawn from the 1998 National Longitudinal Caregiver Survey. The final sample consisted of 1406 community-dwelling male veterans with dementia and their coresiding female informal caregivers. Presence of caregiver psychologic distress was measured using the Boston Short Form of the Center for Epidemiologic Studies Depression Scale. Vaccination was identified by examining Veteran Administration Outpatient Data Files for visits indicating influenza vaccine administration during the 1998 influenza vaccine season (September 1 to December 31). Multivariate path analysis with observed variables was used to estimate direct and indirect probit path coefficients between independent variables, caregiver psychologic distress, and veteran vaccination. RESULTS: As hypothesized, caregiver distress was significantly associated with a decreased likelihood of care-recipient vaccination (unstandardized coefficient [b] = -0.023, P < 0.01). Adjusted for other variables, the predicted probability of vaccination was 37.7% for care-recipients with nondistressed caregivers compared with 29.4% for care-recipients with distressed caregivers. Furthermore, a number of factors significantly influenced vaccination via their influence on psychologic distress. CONCLUSION: We conclude that caregiver psychologic distress may interfere with access to influenza vaccination in persons with dementia. Access to vaccination may be improved directly by detecting and treating emotional health problems in caregivers and indirectly by addressing precursors to caregiver distress.

Aged↗

Patient knowledge, beliefs, and behavior concerning the prevention and treatment of glucocorticoid-induced osteoporosis.

OBJECTIVE: To obtain descriptive information concerning the extent to which patients taking oral glucocorticoids recall receiving osteoporosis prevention counseling, and to identify factors associated with the practice of 3 behaviors (i.e., calcium intake, vitamin D intake, and bone mineral density [BMD] testing) recommended for patients receiving glucocorticoid therapy. METHODS: The study assessed cross-sectional data derived from telephone interviews and mailed questionnaires completed by 227 patients who were currently taking oral prednisone. Questions assessed current calcium and vitamin D intake and history of BMD testing. RESULTS: Approximately one-third of participants (36.3%) reported that they had received osteoporosis prevention counseling. Among those who reported receiving counseling, most (73.2%) remembered being told about the importance of obtaining an adequate amount of calcium. Other topics were remembered less frequently. Slightly more than half of study participants (51.1%) were obtaining the recommended amount of calcium. Fewer were obtaining the recommended amount of vitamin D (35.2%) or had received a BMD test within the past year (33.5%). The most consistent predictors of behavior were counseling status and patients' perceptions of the difficulty associated with performing the behavior. CONCLUSION: Most patients receiving oral glucocorticoids receive insufficient counseling concerning the prevention of osteoporosis; patients either are not being counseled or they are being counseled in a manner that is not sufficient to promote subsequent recall and behavior change. Research is needed to develop effective strategies to educate patients about the prevention of glucocorticoid-induced osteoporosis.

Administration, Oral↗

Effects of media coverage of Women's Health Initiative study on attitudes and behavior of women receiving hormone replacement therapy.

PURPOSE: The effects of media coverage of the Women's Health Initiative (WHI) study on the attitudes and behavior of women regarding hormone replacement therapy (HRT) were studied. METHODS: This cross-sectional observational study took place in 12 counties in western North Carolina from 1997 to 1999. Participants were recruited from among women who participated in a previous study, which examined the effects of osteoporosis education on adherence to prevention guidelines. Women in the current study were limited to those previously reporting postmenopausal status and use of HRT. Participants were interviewed by telephone with a 41-item scripted survey. Main outcomes included primary sources of information regarding HRT, perception of the accuracy of information from various sources, and changes in HRT use. RESULTS: Every woman in the study (n = 97) reported having heard about the WHI study, and 52% reported that it had affected their use of HRT. Women using estrogen alone were as likely as women using an estrogen-plus-progestin combination to have had their use affected (48% versus 59%, respectively). Women making a change after hearing about the WHI study results were significantly less likely to trust information from their physicians regarding HRT. CONCLUSION: A survey of women who had received HRT found that media reports on the WHI study had a significant influence on their use of HRT.

Attitude↗

Factors associated with potentially inappropriate drug utilization in a sample of rural community-dwelling older adults.

BACKGROUND: Many medications present special risks when used by older adults (ie, those aged > or = 65 years) and are considered potentially inappropriate for this population. The Beers criteria are often used to identify such medications. Past research has documented that use of Beers drugs is common among older adults. OBJECTIVE: The aim of this work was to examine factors associated with potentially inappropriate drug use among rural community-dwelling older adults using a conceptual framework adapted from the Andersen-Newman behavioral model of health service use. METHODS: This was a population-based, cross-sectional survey. Data were collected via face-to-face home interviews between 2002 and 2004. Rural community-dwelling older adults residing in a single county in North Carolina were eligible. Potentially inappropriate drug use was operationalized using the Beers criteria. Data concerning predisposing (ie, age, sex, race, education, and marital status), enabling (ie, social support and insurance status), need (ie, disability and history of major depression, hypertension, osteoarthritis, back problems, or other comorbidities), and utilization factors (ie, number of medications used) were collected. RESULTS: Data were gathered from 892 people, with information on medication use available for 800. Two hundred thirteen of these 800 participants (26.6%) used > or = 1 Beers drug. Compared with individuals who used no Beers drugs, those who used > or = 1 Beers drug reported lower levels of social support (odds ratio [OR], 0.94; 95% CI, 0.90-0.99) and higher levels of disability (OR, 1.48; 95% CI, 1.11-1.97), used more medications (OR, 1.07; 95% CI, 1.01-1.13), and were more likely to have a history of major depression (OR, 1.67; 95% CI, 1.05-2.66), hypertension (OR, 1.58; 95% CI, 1.07-2.33), osteoarthritis (OR, 1.58; 95% CI, 1.09-2.29), and back problems (OR, 1.72; 95% CI, 1.19-2.47). CONCLUSION: As suggested by the Andersen-Newman model, the risk of potentially inappropriate drug use is highest among those with the greatest medication needs, as evidenced by poorer health status in this sample of rural community-dwelling older patients.

Adult↗

Toward a better understanding of calcium intake: behavioral change perspectives.

This paper reviews what is currently known about the determinants of calcium intake. The paper focuses on findings from 3 studies conducted from 1994 to 2000 to examine the determinants of calcium intake among women at midlife. These 3 studies used the precaution adoption process model as a theoretical framework. Findings from other studies that have examined the determinants of calcium intake using different theoretical frameworks in different population groups are also presented. The findings reviewed suggest that there is a high level of awareness among women that consuming an inadequate amount of calcium increases their risk of developing osteoporosis but that this awareness is not being translated into long-lasting behavior change. Even when individuals are interested in increasing their calcium intake, perceived barriers often appear to prevent them from acting or lead to recidivism. Thus, in working with patients, clinicians should solicit patient concerns about trying to increase their calcium intake and barriers that the patient has experienced in the past or may anticipate in the future. In addition, this review notes a glaring lack of research concerning calcium intake among men and members of ethnic minorities and calls for future research focusing on more diverse populations.

Calcium, Dietary↗

Development and assessment of a short instrument for assessing dietary intakes of calcium and vitamin D.

OBJECTIVE: To validate a short food frequency screening instrument designed to assess dietary intakes of calcium and vitamin D. DESIGN: Cross-sectional surveys and food diaries. PARTICIPANTS: Twenty-seven university employees. MAIN OUTCOME MEASURES: Calcium and vitamin D intakes of participants were assessed using three instruments: a 7-day food diary, the Block-National Cancer Institute Health Habits and History Questionnaire (HHHQ), and a short screening instrument derived from the HHHQ. The accuracy of participants' reports of calcium and vitamin D intakes on the HHHQ and short screening instrument were checked against the food diaries. The validity of the full survey and the screening instrument were judged according to their correlation with the food diaries. RESULTS: Estimates of calcium and vitamin D intakes derived from the 7-day food diary and the short screening instrument were significantly correlated (r = 0.66 and 0.72, respectively, P < .001). The mean differences between estimates derived from the short screening instrument and those derived from the 7-day food diary were 223 mg/day for calcium and 47 IU/day for vitamin D. The positive predictive value of the short screening instrument in identifying individuals with low nutrient intakes, as assessed by the 7-day food diary, was 91.7% for calcium and 100.0% for vitamin D. CONCLUSION: The short screening instrument provides reasonably accurate estimates of calcium and vitamin D intakes. Although it cannot replace more comprehensive nutritional assessments, the screening instrument may provide quick assessments of calcium and vitamin D intakes. Given that many individuals consume suboptimal levels of these nutrients, pharmacists may use the screening instrument to evaluate patients' needs for calcium and/or vitamin D supplements and, thus, reduce their risk for developing osteoporosis.

Adult↗

Drug therapy concerns questionnaire: initial development and refinement.

OBJECTIVE: To develop a scale, designed for self-administration, to assess patient perceptions of drug therapy problems (DTPs). DESIGN: Cross-sectional survey. SETTING: California Central Valley. PARTICIPANTS: 200 community-dwelling adults taking at least one prescription medication. MAIN OUTCOME MEASURE: 78 items assessing patient perceptions of DTPs. INTERVENTIONS: Self-administered questionnaire completed by study participants. RESULTS: Based on a Medication Evaluation and Response Model proposed in this article, items were developed to assess patient perceptions about potential or actual DTPs. Scales for five of the seven problem domains specified a priori were reliable based on participant responses: Perceived Efficacy, Overmedication Concerns, Adverse Drug Reaction Concerns, Adherence Issues, and Knowledge. Barriers and Intrusiveness were eliminated from, the questionnaire because of weak factor loadings. After making changes in domain assignment and eliminating redundant and weak items, five items remained in each of the five reliable scales, with Cronbach's alpha values ranging from 0.76 to 0.82. Each of the five scales was significantly associated with patient satisfaction with their medications. Individuals who reported fewer DTPs expressed greater overall satisfaction with their medications. In a forward stepwise regression analysis, four of the five scales exhibited independent associations with medication satisfaction, explaining 58.0% of the total variance in satisfaction [F(4,178) = 61.48, P < .0001]. Only the Knowledge scale failed to exhibit an independent association with satisfaction. CONCLUSION: The findings from this initial stage of scale development are encouraging. The association between the scales and medication satisfaction suggests that the scales may be useful in learning more about those factors that influence how patients evaluate their medications.

Cross-Sectional Studies↗

North Carolina family practice physicians' perceptions of pharmacists as vaccinators.

OBJECTIVE: To determine whether family practice physicians are aware that pharmacists can administer vaccines and assess their support of pharmacists as vaccinators. DESIGN: Cross-sectional study. SETTING: North Carolina. PARTICIPANTS: 571 family practice physicians. INTERVENTIONS: Mail survey. MAIN OUTCOME MEASURES: Physician attitudes toward pharmacists' involvement with a variety of vaccines and patient populations. RESULTS: A total of 25% of physicians correctly reported that pharmacists could administer vaccines in North Carolina, a state that had recently passed legislation permitting this practice. Almost 50% of the physicians supported pharmacists administering the influenza vaccine. Pharmacist administration of other vaccines received less support. Physicians who were newer to family practice had more positive attitudes than physicians who were in practice for longer periods of time. CONCLUSION: While agreeing that the role of the pharmacist in patient care is becoming more important, physicians were neither very knowledgeable about nor supportive of pharmacists as vaccinators.

Aged↗

Effects of an osteoporosis prevention program incorporating tailored educational materials.

PURPOSE: To evaluate the effects of two interventions on calcium intake and exercise and assess whether intervention effects varied as a function of participants' stage of change. DESIGN: The study used a 2 by 2 factorial research design. Baseline, 3-, 6-, and 12-month follow-up data were collected. SETTING: Twelve counties in western North Carolina. SUBJECTS: Of 714 women recruited, 547 (76.6%) completed all data collection procedures. INTERVENTION: One intervention, conducted at the individual level, compared the effects of tailored vs. nontailored educational materials. The tailored educational intervention was delivered via two packets of written materials and one telephone counseling session. The written materials and counseling session were tailored according to participants' current calcium intake and exercise level, perceived adequacy of these behaviors, stage of change, behavioral goals, and perceived barriers to change. A community-based intervention was also evaluated. This intervention, implemented in 6 of the 12 counties, included establishing an Osteoporosis Resource Center, conducting a workshop on osteoporosis prevention, and offering free bone density screening. MEASURES: Outcome measures were calcium intake and exercise level. Stage of change was assessed as a moderating variable. RESULTS: Irrespective of intervention group, among women not consuming adequate calcium at baseline, intake increased an average of about 500 mg/d over the course of the study. Changes involving exercise were more modest. Repeated measures regression analyses were used to evaluate intervention effects. The effect of the tailored educational intervention varied, in appropriate ways, among women in different stages of change at baseline (F2,527 = 6.37, p < .002). Among women in the Engaged stage, the tailored intervention was associated with a greater increase in calcium intake. In contrast, among women who were obtaining adequate calcium at baseline (i.e., Action stage), the tailored intervention appeared to forestall inappropriate increases in calcium intake. The community-based intervention had no consistent effects on calcium intake, either alone, or in combination with the tailored intervention. Finally, neither intervention had an effect on exercise, either alone or in combination. CONCLUSIONS: Limited support for the superiority of tailored vs. nontailored educational interventions was found. The differential effects observed could be due to the telephone counseling received by women in the Tailored Education Group, however.

Calcium↗