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Biomedical subjects

Susan M Schneider

Publications and source records attributed to Susan M Schneider.

6 recordsLinked to original sources

Molecular order in concurrent response sequences.

We studied the order of emission of concurrently reinforced free-operant two-response sequences such as left-left (LL) and left-right (LR). The end of each sequence was demarcated by stimulus change. The use of demarcated sequences of responses, as opposed to individual responses, provides an expanded set of distinct, temporally ordered behaviour pairings to investigate (e.g., LL followed by LL, LL followed by LR, etc.); it is as well a real-life analogue. A sequential analysis of new and existing rat and pigeon data revealed patterns in both overall and post-reinforcer-only sequence emission order. These patterns were consistent across species and individuals, and they followed higher-order organising principles. We describe sequence non-repetition, last-response repetition, and the proportion and post-reinforcer effects, and relate them to existing molar and molecular behaviour principles. Beyond their immediate implications, our results illustrate the value of sequential analysis as a tool for the investigation of molar-molecular behavioural relations.

Animals↗

Demarcated response sequences and generalised matching.

The generalised matching law was applied for the first time to sequences of responses. Pigeons responded on dependently arranged two-operandum concurrent schedules in which all four possible two-response sequences on these operanda were demarcated and reinforced. Reinforcer rates for the sequences were varied over a wide range, including extinction. Sequences of responses, rather than individual responses, followed the generalised matching law. We compared single-sensitivity and multiple-sensitivity versions of the generalised matching law. The multiple sensitivities were not significantly different from each other, so the single-sensitivity model provided the more efficient fit. As in previous research, responding was biased against the emission of sequences that required changeovers.

Animals↗

Virtual reality intervention for older women with breast cancer.

This study examined the effects of a virtual reality distraction intervention on chemotherapy-related symptom distress levels in 16 women aged 50 and older. A cross-over design was used to answer the following research questions: (1) Is virtual reality an effective distraction intervention for reducing chemotherapy-related symptom distress levels in older women with breast cancer? (2) Does virtual reality have a lasting effect? Chemotherapy treatments are intensive and difficult to endure. One way to cope with chemotherapy-related symptom distress is through the use of distraction. For this study, a head-mounted display (Sony PC Glasstron PLM - S700) was used to display encompassing images and block competing stimuli during chemotherapy infusions. The Symptom Distress Scale (SDS), Revised Piper Fatigue Scale (PFS), and the State Anxiety Inventory (SAI) were used to measure symptom distress. For two matched chemotherapy treatments, one pre-test and two post-test measures were employed. Participants were randomly assigned to receive the VR distraction intervention during one chemotherapy treatment and received no distraction intervention (control condition) during an alternate chemotherapy treatment. Analysis using paired t-tests demonstrated a significant decrease in the SAI (p = 0.10) scores immediately following chemotherapy treatments when participants used VR. No significant changes were found in SDS or PFS values. There was a consistent trend toward improved symptoms on all measures 48 h following completion of chemotherapy. Evaluation of the intervention indicated that women thought the head mounted device was easy to use, they experienced no cybersickness, and 100% would use VR again.

Adaptation, Psychological↗

Cancer-related fatigue.

Approximately 1.3 million people in the United States will be diagnosed with cancer in 2003 and millions of other individuals are already living with the disease. Fatigue continues to be the most prevalent and disruptive symptom of cancer and its treatment regimens. Fatigue was the most frequent and distressing cancer-related symptom occurring in women with lung cancer, two times greater than the next symptom, pain, and remains one of the most common symptoms in newly diagnosed lung cancer patients at any stage of the disease. There are many causes of cancer-related fatigue including preexisting conditions, physical and psychological symptoms caused by cancer, and the consequences of cancer treatment. High levels of fatigue decrease quality of life, physical functional status, and symptom management. This article presents an evidenced-base review of cancer-related fatigue, strategies for the management of cancer-related fatigue, and recommendations for clinical practice.

Adult↗

Chemotherapy-induced nausea and vomiting.

Nausea and vomiting (N&V) is among the most distressing side effects of chemotherapy, despite the development of more efficacious antiemetic agents. As many as 60% of patients who receive cancer chemotherapy experience some degree of N&V. However, the actual incidence is difficult to determine with accuracy because of the variety of drugs, doses, and health conditions of the patients who receive cancer treatments. This article examines the state of the science related to chemotherapy-induced nausea and vomiting and reviews both pharmacologic and behavioral strategies that have demonstrated efficacy in managing these distressing symptoms.

Antiemetics↗

Virtual reality as a distraction intervention for women receiving chemotherapy.

PURPOSE/OBJECTIVES: To explore the use of virtual reality as a distraction intervention to relieve symptom distress in women receiving chemotherapy for breast cancer. DESIGN: Crossover study. SETTING: The outpatient clinic of a midwestern comprehensive cancer center. SAMPLE: 20 women 18-55 years of age. METHODS: Using a crossover design, 20 subjects served as their own controls. For two matched chemotherapy treatments, one pretest and two post-test measures were employed. Participants were assigned randomly to receive the virtual reality distraction intervention during one chemotherapy treatment and received no distraction intervention (control condition) during an alternate chemotherapy treatment. An open-ended questionnaire elicited each subject's evaluation of the intervention. MAIN RESEARCH VARIABLES: Symptom distress, fatigue, anxiety. FINDINGS: Significant decreases in symptom distress and fatigue occurred immediately following chemotherapy treatments when women used the virtual reality intervention. CONCLUSIONS: The distraction intervention decreased symptom distress, was well received, and was easy to implement in the clinical setting. IMPLICATIONS FOR NURSING: Nursing interventions to manage chemotherapy-related symptom distress can improve patient quality of life and increase chances for survival by reducing treatment-related symptom distress and enhancing patients' ability to adhere to treatment regimens and cope with their disease.

Adaptation, Psychological↗