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Biomedical subjects

Syed Husain

Publications and source records attributed to Syed Husain.

6 recordsLinked to original sources
PubMed2006

Gastric bypass in a factor V deficient patient.

Factor V deficiency is a rare bleeding disorder requiring special attention during the peri-operative period. Surgical intervention in these patients can be technically challenging. Because of the rarity of this condition, the optimal management is unknown. Available literature supports peri-operative infusion of fresh frozen plasma. We report successful management of a factor V deficient patient undergoing Roux-en-Y gastric bypass. Literature review indicates that this is the first reported case of bariatric surgery in a patient with factor V deficiency.

Adult↗
PubMed2006

Tumescent technique for burn wound debridement: a cost effective method of reducing transfusion requirements.

A technique is defined to validate the efficacy of subeschar epinephrine tumescence in reducing blood loss during burn wound debridement. It was done at the Department of Plastic Reconstructive Surgery, Harlem Hospital Center, New York City involving two consecutive patients at Burn Intensive Care Unit with full thickness and deep partial thickness burns involving greater than 60% body surface area. Subeschar infusion of 1:10,00,000 solution of epinephrine was achieved prior to tangential debridement. Predicted and actual blood loss was calculated using Desai's formulas. Subeschar epinephrine tumescence prior to debridement produced an average of 39.25% reduction in blood loss.

Adrenergic Agonists↗
PubMed2006

Adnexal mass: an unusual presentation of small-bowel adenocarcinoma.

Malignancy of the small bowel presents unique diagnostic and therapeutic challenges resulting in a delayed diagnosis in many cases. Small-bowel tumors respond poorly to most forms of treatment. Metastatic lesions to the ovaries comprise a small percentage of all ovarian malignant neoplasms. Ovarian metastases from primary small-bowel tumors are often difficult to differentiate from primary ovarian tumors. Only few reports have described ovarian metastases from small-bowel sources. A high index of suspicion can lead to an earlier diagnosis and can have an impact on the therapeutic options as well as the survival of the patients. The current report also underscores the importance of careful review of symptoms, investigative studies and pathology.

Abdominal Pain↗
PubMed2002

Positron emission tomography in the evaluation of synchronous lung lesions in patients with untreated head and neck cancer.

BACKGROUND: Positron emission tomography (PET) with the glucose analogue fludeoxyglucose F 18 uses the increased glucose uptake that is observed in neoplastic cells. It can differentiate between benign and malignant pulmonary lesions in patients with lung tumors. Applications of PET in extracranial head and neck neoplasms have included evaluating patients with unknown primary lesions, detecting primary and recurrent head and neck tumors, monitoring response to radiotherapy, and evaluating the N0 neck in oral cavity carcinomas. Its role in determining the presence of synchronous lung lesions has not been defined. PATIENTS AND METHODS: A retrospective review of 115 patients who underwent PET between October 1994 and October 1996 was performed to evaluate extracranial head and neck neoplasms. Fifty-nine (51%) previously untreated patients with squamous cell carcinoma of the upper aerodigestive tract were analyzed. RESULTS: Fifteen patients (25%) had PET scans that were positive for synchronous lung lesions. Five patients had a disease process that did not warrant further investigation; they did not have pathological confirmation of their lung lesions. Of these, 3 died of disease within 2 months of the diagnosis of primary head and neck squamous cell carcinoma, 1 was unavailable for follow-up, and 1 had lung lesions that were considered metastatic and no pathological confirmation of lung lesions was obtained. The remaining 10 patients with positive PET scan findings were investigated further: 8 patients had biopsy-confirmed lung lesions; 5 patients had positive findings on chest x-ray films; 8 had positive findings on computed tomographic scans; and 3 had positive findings on bronchoscopy. The results of 2 PET scans were false-positive. The PET scans were important in altering treatment in 3 patients; of these, 3 had negative findings on chest x-ray films, 2 had positive findings on computed tomographic scans, and 1 had positive findings on bronchoscopy. CONCLUSIONS: The overall sensitivity, positive predictive value, and accuracy of PET were 100%, 80%, and 80%, respectively. The overall accuracy of radiography of the chest, computed tomography of the chest, and bronchoscopy was 70%, 90%, and 50%, respectively. The accuracy of PET over bronchoscopy was statistically significant (P<.05). PET appears to be a promising imaging modality for the detection of synchronous lung lesions in patients with negative findings on chest x-ray films.

Adult↗