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Biomedical subjects

T A Evdokimova

Publications and source records attributed to T A Evdokimova.

At least 19 recordsLinked to original sources

[Characteristics of response to isometric exercise in women with stable arterial hypertension].

In 50 females with Stage II persistent hypertension, tetrapolar thoracic rheography was employed to measure cardiac index (CI), stroke index (SI), specific peripheral resistance (SPR), blood pressure (BP), heart rate (HR) before and during isometric exercise when antihypertensive drugs were withdrawn. The patients with a family history of hypertension were found to have impaired homeostatic mechanisms preventing an excess elevation in BP during isometric exercise. The females of reproductive age showed a greater increase in BP, HR, SI, CI and a lower decrease in SPR in response to the exercise than did menopausal females. Left ventricular hypertrophy contributes to a positive inotropic action shown by sympathetic cardiac stimulation during isometric exercise, as evidenced by a lower reduction or elevation in SI. The detected responses to isometric exercise may serve as criteria for differential approach to the choice of adequate antihypertensive therapy.

Adult↗

[Multifactorial analysis of the hemodynamic reactions to a physical load in hypertension].

Multifactorial analysis of findings from 66 essentially hypertensive patients and 14 normal subjects investigated during bicycle ergometry (250 and 500 kgm/min) demonstrated a relationship between hemodynamic changes and the patient's baseline status, age and stage of the disease. Hypertensive patients showed greater AP response to exercise and smaller changes in heart productivity and vascular tone, as compared to normal subjects with similar resting hemodynamic status. Patients with high resting AP and CI values showed smaller shifts during bicycle ergometry, as compared to other patients at the same stage of the disease, while diastolic AP increase was more pronounced in elderly patients.

Adult↗

[Integration of motor and autonomic functions during muscle work].

In isometric efforts small energy expenditure was found to involve an inadequate increase of the heart rate and blood pressure. In dynamic cyclic loads, the heart rate and blood pressure increase occurs linearly, corresponding to the increase of O2 consumption and systolic index. Voluntary relaxation of muscles in the course of cyclic load involves small values of the O2 consumption and systolic index, as well as low heart rate and blood pressure. In natural cyclic and noncyclic motor activity, the character of integration of the motor and vegetative functions depends on the relative weight of each of the biomechanical modes.

Adolescent↗

[Physical loading in the diagnosis and evaluation of the efficacy of treatment of hypertension].

On the basis of the study into the parameters of systemic hemodynamics during bicycle ergometric exercise, and their processing with the help of the programme of multiple step-wise regression in computer CM-3, an algorithm was derived whose employment makes it possible to determine very reliably the severity of the disease, and which also facilitates an early diagnosis of essential hypertension and reflects the effectiveness of the therapy.

Adult↗

[Respiratory responses to different human movements].

Respiratory responses to different movements and postures become stabilized according to the respiratory-energy demands of the optimal way for task solution. Passive pedalling entails diminishing of electrical activity, the respiratory reactions at that being significantly higher than at resting but lower as compared to active work. With no circumstantial (sporting) stimuli, the increase of respiratory responses to muscular relaxation in the course of pedalling was as significant as the cardiac outflow volume. Maximal and minimal values of the blood pressure did not change. The circumstantial conditioned stimuli enhanced the respiratory responces both at resting and during passive pedalling.

Blood Pressure↗

[Central and renal hemodynamic indices under physical load in hypertension].

The article shows the results of studying the functional condition of the cardiovascular system in hypertensive disease. Under physical load healthy individuals demonstrated an increase in arterial pressure, rate of cardiac contractions, cardiac and stroke output, arteriovenous difference in oxygen, and diminution in the circulation volume, total peripheral resistance, renal blood flow and renal fraction of the minute blood volume. In patients with hypertensive disease there was a tendency to a lesser decrease in the cardiac output under load, the difference with the indices of healthy individuals increased with each stage of the disease. In hypertensive disease of stage IIB there were significantly smaller cardiac output, diminution of stroke volume under load, and a sharper rise than in the control group of arteriovenous difference in oxygen. The diminution of renal blood flow in response to the load was more marked in hypertensive disease.

Adult↗

[Supravascular laser exposure in combined modality treatment of patients with arteriosclerosis obliterans of blood vessels of lower extremities].

The efficiency of supravascular laser exposure in multiple-modality treatment of patients with atherosclerosis obliterans with distal vascular lesions is demonstrated and the method of noninvasive laser exposure of the lower limbs is validated. Difficulties in the treatment of this category of patients prompted supplementing traditional therapy by supravascular laser exposure in 32 patients. No laser therapy was used in the controls.

Arteriosclerosis Obliterans↗