Serum immunoglobulins in the differential diagnosis between intrahepatic viral jaundice and extrahepatic obstructive jaundice.
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Biomedical subjects
Publications and source records attributed to T A Fox.
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The anatomy of the perianal connective tissue has been reviewed. The most important element is the conjoined longitudinal coat, the axis of the connective-tissue system. Fibers of the longitudinal coat penetrate the internal and external sphincter, interlacing with each other as well as the perimysium and endomysium and forming a fibroelastic network. The fibers and bundles of the internal and external sphincters lie in the meshes of this network with innumerable attachments to it. The fibroelastic network continues through the perianal fat to the pelvic wall and is connected to the lower levator fascia and the perianal skin, insuring the firm anchoring of the anus. During sphincter contraction the fibroelastic network moves together with the sphincters. Thus, the sphincter function is the integration of the contraction of the muscle fibers attached to the web. The elastic elements of the network pull the anal canal slightly apart, but the muscle tone overcomes this and keeps the anus closed. Surmounting the elasticity of the web causes the muscle function to be elastic as well. Surgical procedures such as stretching, transecting the sphincters, whether sharply or gradually, can lead to scar formation with loss of elasticity or mobility in that part of the sphincter and secondary impairment of function.
Two cases of subcutaneous emphysema of the left lower extremity secondary to perforations of the rectum ,nd sigmoid colon are presented. Although this is an extremely rare syndrome, the true incidence is probably higher, as some cases will be misdiagnosed as gas gangrene unless careful clinical and postmortem examinations are performed. Only rapid recognition of the probable origin of the gas, coupled with aggressive, definitive therapy, can prevent the usually fatal course of this condition. In the absence of trauma to the chest or infection in a previously normal leg, subcutaneous emphysema of a limb should alert the physician to the possibility of a gastrointestinal perforation as a source of the gas. Perforations of the gastrointestinal tract into the subcutaneous tissue can occur anywhere from the neck to the lower extremities.
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Problems of sexual dysfunction were surveyed by questionnaire mailed to women who had undergone rectal resection and ostomy surgery over a ten-year period. Completed questionnaires were returned by 30 respondents, 19 to 54 years of age, who indicated both physical and psychological problems. Many of the problems were solved by the patients themselves, but the way can be made easier with the help of an understanding surgeon and knowledgeable stoma therapist who can create a climate in which the patient may feel at ease asking for guidance concerning sexual matters.
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