Biomedical subjects
Publications and source records attributed to T A Hudnik-Plevnik.
Explore the source record for details and available documents.
Analyses of the time of recombination in bacteria infected with phage lambda and in spheroplasts infected with purified phage lambda DNA indicate a preponderance of recombination occurring before replication ("early recombination") after infection with tandem dimers formed in vitro compared to linear monomer DNA and phage infections. Among the early recombinants is a large fraction of cells that produces one recombinant type exclusively. Two suggestions are discussed-that a dimer-like molecule is the precursor of the recombinant progeny molecule and that one recombinant chromosome is the frequent or exclusive product of a recombinational event.
After irradiation, nearly equal amounts of deoxyribonucleic acid (DNA) are synthesized in radiation-sensitive Salmonella typhimurium and in resistant Escherichia coli B/r. However, the DNA synthesized in S. typhimurium is of low molecular weight, whereas that made in the E. coli B/r is like that synthesized in the unirradiated controls.
Explore the source record for details and available documents.
Salmonella typhimurium LT-2 was compared with radioresistant (B/r) and radiosensitive (B(s-2)) strains of Escherichia coli in respect to the survival, deoxyribonucleic acid (DNA) breakdown, and DNA synthesis after X irradiation. It is shown that S. typhimurium LT-2 is about four times more sensitive than E. coli B/r but less sensitive than B(s-2). The DNA breakdown is in S. typhimurium LT-2 lower than the postirradiation breakdown of DNA in both E. coli strains and DNA synthesis proceeds in this bacterium in spite of a much lower survival, as in the radioresistant E. coli B/r.
Explore the source record for details and available documents.
Explore the source record for details and available documents.