PubMed Health⌕ Search

Biomedical subjects

T A Lukina

Publications and source records attributed to T A Lukina.

At least 19 recordsLinked to original sources
PubMed1987

[Possibilities for defining dysplastic changes in the gastric mucosa during cytologic studies of gastric biopsies].

The authors compared the data of cytologic and histologic studies of gastric biopsy material from 95 patients with different degree of epithelial dysplasia revealed histologically. Differentiation impairment and epithelial cell atypia can be revealed in cytologic preparations; basing on these features epithelial dysplasia was diagnosed cytologically in 40 patients (30 of them with adenomas). Cytological and histological diagnosis of epithelial dysplasia did not fully coincide. The most reliable are the cytological features of severe dysplasia, thus the main goal of a morphologic study is achieved. One should not identify the term "dysplasia" in a cytologic study with a term "proliferation". Gastric biopsy material may have the following cytologic characteristics: tegmental-fossa epithelium proliferation, marked proliferation of tegmental-fossa epithelium with atypia, epithelial dysplasia and such epithelial dysplasia when cancer is not ruled out.

Biopsy↗
PubMed1985

[Cytological diagnosis of epithelial dysplasias].

The attempt is undertaken to determine the possibilities of the dysplasia cytological diagnosis taking as an example the gynecological smears, smears-prints of the gastrobiopsies and mammary gland punctures. The difficulties are noted with which the cytologist is faced. The correctness of the cytological diagnosis "epithelial proliferation with atypia" and the possibilities of using the term "severe dysplasia" in the pronounced epithelial cells alterations, signs of their disordered differentiation is pointed out.

Breast Neoplasms↗
PubMed1984

[Not Available].

Explore the source record for details and available documents.

Historiography↗
PubMed1981

[DNA content of gastric mucosal epithelium in various diseases].

Evaluation of DNA content in superficial epithelial cells of gastric mucosa by gastrobiopsy using the flow-through cytophotometric method revealed some differences in the distribution of DNA values in benign and carcinoma cases. The polymorphism of epithelial cells in benign gastric disorders is accompanied, as a rule, by an increase in the amount of cells in S and G2 + M phases of the cell cycle. In the cases with epithelial cell atypia, a small peak in the hypertetraploid range is often seen and DNA-histograms are identical with those in carcinoma of the stomach. Malignant specimens usually have an increased 3n and 4n DNA level and an obvious third peak at the hypertetraploid level. Different forms of carcinoma (adenocarcinoma and undifferentiated form) have their own distinguishing features in DNA content distribution.

Adenocarcinoma↗
PubMed1980

Flow cytofluorometry, cytomorphology and histology in gastric carcinoma.

68 cases of gastric carcinoma and 31 tissue samples adjoining the carcinomas were investigated by impulse cytophotometry, cytomorphology and histology, respectively. Differentiated adenocarcinoma tended to aneuploidy, while undifferentiated carcinoma often showed euploidy. The adjoining mucosa was characterized by polymorphism of the mucosa superficial epithelial cells and the histograms showed slight abnormalities.

Adenocarcinoma↗
PubMed1979

[Standardization of the cytological conclusions in the diagnosis of cancer of the lung, stomach, breast and thyroid gland].

Based on a correlation of the results of cytological and histological assays in 1213 patients, the authors have analysed the correct and erroneous verifications of the cancer pattern according to cytological preparations. Under consideration are the possibilities and limitations of the cytological verification of different histological patterns and degree of differentiation of cancer of the lung, stomach, breast and thyroid. Standard cytological conclusions in accordance with the suggested cytological classifications of cancer of these organs are discussed.

Adenocarcinoma↗
PubMed1975

[Not Available].

Explore the source record for details and available documents.

Academies and Institutes↗