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Biomedical subjects

T A Morsy

Publications and source records attributed to T A Morsy.

At least 19 recordsLinked to original sources

The larvicidal activities of the peel oils of three citrus fruits against Culex pipiens.

The larviciddal action of three ethanol extracts of peel oils of lemon, grapefruit and navel orange were tested against the early 4th instar larvae of Culex pipiens and the resulting pupae. The LC50 were 18.5, 20.3 and 26.5 and the slope functions were 2.9, 2.9 and 3.9 respectively. The action of the lemon extract extended to the pupae which resulted from larvae exposed to sublethal dose. Some of the pupae were unable to escape from the larval exuviae.

Animals

Human taenaisis and cysticercosis in slaughtered cattle, buffaloes and pigs in Egypt.

Human taeniasis and cysticercosis are zoonotic parasites of considerable public health problem. A total of 6434039 slaughtered animals over a period of four years (1994-1997) showed 0.72% cysticercosis (bovis and cellulosae) infections. Individual animal species infection was 0.23% in native breed cattle, 7.25% in imported cattle, 0.14 in buffaloes and 0.09% in pigs. The highly infested parts were the heart (64.2%) followed by the head (34.5%), the whole body (1.1%) and lastly, the quarter (0.2%) in both types of cattle and the heart (64.3%), the head (34.9%), the whole body (0.6%) and the quarter (0.2%) in buffaloes. In pigs, the highly infested parts were the whole body (55.4%) followed by the heart (37.8%) and lastly the head (6.8%). Some interesting cysticercosis were macroscopically and microscopically parasitologically and histopathologically studied. A general discussion on taeniasis and cysticercosis was given.

Abattoirs

Feather and nest mites of two common resident birds in two ecologically different Egyptian governorates.

The study of the role played by birds in the distribution of various bacterial, viral and parasitic infections is increasingly from year to year, taking into consideration the flying ability of birds and their migration for food and vital processes. Two of the common Egyptian resident birds, house sparrow (Passer d. niloticus) and laughing dove (Streptopelia s. aegyptiaca) were chosen to study their mite fauna. The overall mite index was 4.74 on the house sparrow and 7.22 on the laughing dove. As to mites, a total of 31 species belonging to 23 genera, 17 families and 3 suborders were collected. The common mites on both types of birds were 22 species. Three species only on house sparrow, and six species only on laughing dove. The house sparrow served host for 25 mite species and the laughing dove served host for 28 mite species. The infestation rates of mites on house sparrow ranged between 1.11% to 23.33% and 0.21% to 34.54% in Sharkia and Qalyobia governorates respectively. For laughing dove, the mite infestation rates ranged between 0.82% to 50% and 3.45% to 55.17% for both governorates respectively. Some of the collected mites have medical and/or veterinary importance. The whole results were discussed.

Animals

Vertebral unilocular hydatidosis in a shepherd and his wife.

This paper reports vertebral unilocular hydatid cysts in a shepherd and his wife in Sharkia Governorate. Diagnosis was based on parasitological examination of the surgically removed cysts. Albendazole was given as postoperative treatment. MRI six months after treatment, showed no recurrence and mild clinical improvement.

Adult

Studies on myiasis producing flies collected by bait traps at Al Marg (Qalyobia Governorate), Egypt.

Myiasis is a real welfare problem. As a disease, it affects man and animals. In a study of myiasis producing flies in Al Marg District, sixteen species of dipterous flies were trapped. The predominant species was Musca domestica followed by Lueilia sericata and the least abundance was Wohlfahrtia magnifica. The overall abundance was in Summer followed by Spring and the least was in Winter. The most attractive bait was liver for members of family Calliphoridae and meat for members of family Muscidae and Family Sarcophagidae.

Animals

Myiasis caused by Cephalopina titillator (Clark) in slaughtered camels in Al Arish Abattoir, North Sinai governorate, Egypt.

The oestrid fly or the camel nasal botfly Cephalopina titillator (Clark) is an insect that causes health hazards in camels. No doubt, camels are very important livestock particularly in arid and semi-arid lands. In this paper, the monthly and seasonal prevalence of C. titillator larvae in slaughtered camels were studied. The rate of camel infestation was 25%. The highest prevalence month was October and the highest prevalence season was Autumn. The three larval instars were demonstrated in the infested camels. However, the 3rd instars were the predominant stage (60.59%), followed by the 2nd instars (30.58%) and then the 1st instars (8.83%). In general, some myiasis producers are zoonotic parasites. Nevertheless, the control of the adult C. titillator and its larval instars is a must for the sake of the animal and for the human welfare.

Animals

The histopathological picture of the liver of hamsters experimentally infected with Leishmania D. infantum on top of Schistosoma mansoni infection.

No doubt, double and triple infection in a patient is not an uncommon phenomenon in the Old World. Consequently, the histopathological picture of the liver of Syrian golden hamsters experimentally infected with Leishmania. d. infantum on top of pre-infection with S. mansoni was studied. The results showed that the liver was markedly affected by the concomitant infection than infection with either parasite alone. The superadded Leishmania infection caused the early appearance of cell necrosis and fatty changes. The schistosomal granulomas were rounded in shape and well circumscribed. However, they were smaller in size and less in number when compared with schistosomal control. Also, there was a comparative decrease in the number of their cellular constitutions but without changing in the cell types. The schistosomal granulomas were surrounded with a rim of amastigotes laden macrophages. On the other hand, the leishmanial granulomas, were irregular in shape but comparatively increased in size and in number on the behalf of the schistosomal granulomas. Their cellular constitutions comparatively increased as well. So, it is concluded that the L.d. infantum infection on the top of S. mansoni infection suppressed the schistosomal pathological picture in the liver of hamsters.

Animals

Renal changes in golden hamsters experimentally infected with Leishmania D. infantum on top of Schistosoma mansoni infection.

In Egypt, Schistosomiasis mansoni is one of the most important parasitic disease of man. Besides, in the last two decades, indigenous cases of infantile visceral leishmaniasis have been reported. These two parasites affect the kidney causing renal histopathological changes. Thus, it was aimed to study the concomitant infection of L. d. infantum on top of S. mansoni infection in Syrian golden hamsters, the model animal for both parasites. The results showed that the renal changes were more or less the same as infection with either parasite alone. Both parasites produce mesangial cell proliferation and mesangial matrix increase. Some glomeruli showed complete replacement of the capillary tuft with structureless homogenous material. In one S. mansoni positive control hamster Schistosoma eggs were seen within granulomas and atrophic glomeruli. However, the lesihmanial infection, more or less suppressed the schistosomal infection. The leishmanial infection itself became more prominent and the renal changes it caused appeared earlier and were more obvious.

Animals

Efficacy of ivermectin on the infectivity of Leishmania major promastigotes.

Ivermectin is widely used as an antiparasitic drug for livestock and recently used for some human parasites. The effect of ivermectin on the infectivity of Leishmania major promastigotes was studied in Syrian golden hamsters. The results showed that hamsters infected with promastigotes treated for one day with 100 micrograms/ml ivermectin in culture medium did not develop skin lesion at the site of infection. However, amastigotes were demonstrated in Giemsa stained splenic smears. On the other hand, promastigotes treated for two days with 90 micrograms/ml ivermectin did not acquired the infection. i.e. the promastigotes died or lost their infectivity.

Animals

The histopathology of the intestine in hamsters infected with Leishmania D. infantum on top of pre-existing schistosomiasis mansoni.

In general, both Schistosoma mansoni and Leishmania, d. infantum affect more or less the same human organs. While the liver is the main organ affected, the intestine follows in importance. In the present study, L.d. infantum on tip of pre-existing S. mansoni in Syrian golden hamsters had delayed the appearance of both schistosomal and leishmanial granulomas in the intestine the positive control with either parasite alone. However, the leishmanial infection suppressed the schistosomal infection. Nevertheless, both types of granulomas caused shortening and broadening of the intestinal villi. The concomitant infection with leishmaniasis infantum and schistosomiasis mansoni promote the development of many pathological changes (liver, kidneys, intestine, blood picture etc.). No doubt, these changes lead to marked changes in the typical clinical picture of both parasites. Consequently, parasitological diagnosis of visceral leishmaniasis in concomitant infection is a must as in a case of VL. and HIV.

Animals

The goat warble fly, Przhevalskiana silenus (Brauer) in north Sinai, Egypt.

During monthly visits to North Sinai, a total of 43 living goats out of 2040 (2.11%) were found infested with Przhevalskiana silenus (Brauer). This was mainly in Winter. Besides, nodule caused of P. silenus larvae were recovered from 32 out of 98 (32.65%) slaughtered goats in Al Arish abattoir mainly in Summer. The overall infestation rate among slaughtered goats was 11.68 percent. On the other hand, adult flies were collected by baited traps from Bir Al Abd and Al Hasanah in late Spring and early Summer. It is concluded that myiasis is a real economic problem which affects the livestock.

Animals

The pathology of the heart and lung in Syrian golden hamsters experimentally infected with Leishmania d. infantum on top of pre-existing Schistosoma mansoni infection.

No doubt, double and triple infections are not uncommon features in some of the developing countries. In this paper, the effect of leishmanial infantum and schistosomal mansoni infection on the heart and lung of hamsters promoted many changes not seen in positive control with either parasite alone. Of these important changes, were the presence of leishmanial cardiac granulomas and earlier pulmonary granulomas in the lung were more or less the same as in positive schistosomal control. No doubt, with pulmonary schistosomiasis mansoni dangerous disease. Moreover, additional infection with pulmonary leishmaniasis increases the dramatic clinico-pathological picture.

Animals

The effect of the volatile oils of Chenopodium ambrosioides and Thymus vulgaris against the larvae of Lucilia sericata (Meigen).

Nowadays, there are many problems with the use of chemical insecticides as resistance, environmental pollution, toxicity to man and animal... etc. All these required the investigation of a new line for controlling arthropod pests of medical and agricultural importance. The volatile oils of Chenopodium ambrosioides (American wormseed) and Thymus vulgaris (Tyme) proved to be effective against the third stage larvae of Lucilia sericata. The LC50 confidence limits were 70 ppm and 130 ppm for both volatile oils respectively. No doubt, the use of these plant volatile oils, which are widely distributed in the Egyptian flora, more cheap, more safe and without any pollution or hazard, is recommended.

Animals

Spinal cord hydatid cysts in Egypt.

Hydatid cysts or hydatidosis is a cyclozoonotic parasite, where dog is the definitive host and man is an incidental intermediate host. Human hydatid cysts have been encountered in many organs but the most prevalent is the liver followed by the lung. In this paper, we report for the first time spinal cord hydatid cysts in two preparatory school pupils. They were presented with sever back pain, bilateral neurologic deficient in both lower limbs including motor and sensory affection in scattered pattern as well as knees reflux. The two cases were diagnosed hydatidosis by surgical removal of the cysts and confirmed by histological and parasitological examinations. It is concluded that parasitic infection in the spinal cord is rare but it should be in mind with disseminating parasite(s).

Adolescent

Studies on hydatidosis in slaughtered camels in Egypt.

Hydatid cyst or hydatidosis is a cyclozoonotic parasite of worldwide distribution. Human and animal cases have been reported in Egypt by many authors. Also, the tape worm Echinococcus granulosus has been reported in stray dogs. The present work studied hydatidosis in 400159 camels imported from Sudan over five years (1992 to 1996) and slaughtered in governmental abattoirs under the supervision of GOVS. The overall annual prevalence rates of camel infection were 5.5% (1992), 6.1% (1993), 6.7% (1994), 8.2% (1995) and 4.3% (1996). The most predicted site of infection was the lung followed by the liver. Cystic infection in other organs were rarely seen. The fertility of the cysts was 29% and 20% in lung and liver respectively. Macroscopic and microscopic studies of some interesting cysts were done. No doubt, hydatidosis is a public health problem that affects also the human welfare and economy. The preventive and control measures for man and animal were discussed.

Abattoirs

The larvicidal activity of solvent extracts of three medicinal plants against third instar larvae of Chrysomyia albiceps.

Four solvent extracts of each of Lemongrass (Symbopogon citratus), Santonica (Artemisia cinae) and Pomegranate (Punica granatum) were tested against the 3rd instar larvae of Chrysomyia albiceps. The pomegranate extracts showed the larvicidal activity with LC50 ranging between 25 ppm (acetone extract) and 280 ppm (chloroform extract). The Santonica showed larvicidal activity with LC50 ranging between 48 ppm (ethanol extract) and 380 ppm (acetone extract). The Lemongrass showed activity with LC50 ranging between 135 ppm (ethanol extract) and 570 ppm (chloroform extract). So, the most effective action in accordance to LC50 were the acetone extract of pomegranate, followed by ethanol extract of Santonica and lastly ethanol extract of Lemongrass. The slope functions of these three extracts were 4.6, 2.8 and 8.22 respectively. The shift to insect control by plant extracts pave the way to a somewhat healthy environment.

Animals

Rodents, their seasonal activity, ecto- and blood-parasites in Saint Catherine area, South Sinai Governorate, Egypt.

Rodents are on the top of animal reservoirs of zoonotic parasites. Five species of wild rodents were trapped on monthly base from Saint Catherine area. The highest trap index was 0.5 in May and the lowest was zero in December, January and February. The dominant rodents were Acomys c. dimidiatus followed by Dipodillus d. dasyurus and then A. r. russatus. Sporadic numbers of Sekeetamys c. calurus (3) and Eliomys. qu. melanurus (2) were collected. The ectoparasites in a descending order of abundance were mites (45.6%), lice (30.3%) and then fleas (24.1%). The most abundant ectoparasites among the three groups were Polyplax spinulosa (lice). Allodermanyssus sanguineus (mites), and Xenopsylla dipodilli (fleas). Leishmania amastigotes and Babesia microti were detected in Acomys. Also, one pregnant female A. c. dimidiatus was infected with a nematode parasite, Syphacia obvelata. The results were discussed on the light of the previous work.

Animals

Epidemiological, clinical and laboratory studies on parasitic infections as a cause of fever of undetermined origin in Dakahlia Governorate, Egypt.

Forty-three patients who fulfilled the international criteria for prolonged fever were exposed to thorough history taking, clinical and laboratory investigations. The latter included urine and stool examination, urine and blood culture, haemogram, liver and renal function tests, chest X-ray, tuberculin test, bone marrow, liver biopsy, blood films, serological tests including ELISA, IHA and IFA for detection of schistosomiasis, toxoplasmosis and malaria. Parasitic infections were detected in 30/43 (69.7%), 55.8% of whom had pure parasitic infection and 14% had in addition other causes. The majority of cases with positive etiology were coming from rural areas. The pattern of fever was predominantly intermittent especially with malaria and schistosomal cases. Fever of 21-41 days duration was noted in 70% of patients and 23.3% lasted up to more than 56 days. Visceromegaly (hepatomegaly and/or splenomegaly) was observed in all patients except one case. Lymphadenopathy was detected in ten cases, six of whom were visceral leishmaniasis. The IHA test for leishmaniasis detected ten cases at titres of 256, 512 and 1024 reciprocally. The dot-ELISA gave seropositivity in only 8/10 cases diagnosed by IHA test. So eight cases of VL were diagnosed by two serological tests at high titres. The detection of seropositive cases of visceral leishmaniasis in the studied area, suggests a focus or foci and warrants epidemiological study to establish the actual situation. Generally speaking, parasitic aetiology should be in mind in any case of FUO in Dakahlia. Serological tests are valuable, simple and safe tools for conforming the diagnosis of schistosomiasis, leishmaniasis, toxoplasmosis and malaria.

Adolescent