Biomedical subjects
T A Prankerd
Publications and source records attributed to T A Prankerd.
Folate supplements during pregnancy.
In a controlled, prospective trial, the effects of giving ferrous sulphate 50 mg daily to 76 pregnant women was compared with giving ferrous sulphate 50 mg daily plus folic acid 0.5 mg daily to 82 women in 12 general practices in South-east England.No differences in obstetric complications were found between the two groups, although the evidence of some of the listed complications may be too rare for detection in a sample of patients of this size.
Quality and quantity of survival in acute myeloid leukaemia.
The quality of life in leukaemia is as important as its quantity. In fifty-one patients the quality and quantity of life were improved by less aggressive treatment than is usual. By not trying to induce complete remission at all costs, the mobidity and early mortality were reduced and at least an equivalence in survival was obtained.
Morbidity and mortality in pseudopolycythaemia.
A follow-up of 35 patients with pseudopolycythaemia showed that symptoms, high packed-cell volumes, and low plasma volumes persisted in most patients. The death-rate in these patients was six times greater than expected. Patients with pseudopolycythaemia are often regarded as having a good prognosis; however, this view should be revised in the light of these findings.
Red cells and their enzymes.
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The value of folic acid supplements in pregnancy.
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Diagnosis and treatment of primary polycythaemia.
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Enzyme assays in diseases of erythrocytes.
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Daunorubicin in acute leukaemia.
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Extracorporeal irradiation in the treatment of acute leukaemia.
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Haematology. Time for reappraisal?
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Extracorporeal irradiation in acute leukaemia in adults.
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Some aspects of the pathogenesis of hereditary haemolytic diseases.
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Inherited thrombocytopenia with thrombasthenia.
A family with congenital thrombocytopenia is described through four generations where the mode of inheritance appears to be an autosomal dominant. Spontaneous bruising of varying severity, menorrhagia, and profuse bleeding at operation necessitating transfusion were predominant in the history. Platelet function tests were performed on the various patients. Platelet aggregation by adenosine diphosphate (ADP) was found to be defective, though liberation of platelet factor III and platelet thromboplastic function were found to be normal when corrected for deficient numbers.
The management of myelomatosis.
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