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Biomedical subjects

T A Spitsyna

Publications and source records attributed to T A Spitsyna.

5 recordsLinked to original sources

[Use of cephalosporins for the prevention of mixed infection during surgical treatment of rectal cancer].

Cephalosporin antibiotics such as cephaloridine, cephazolin and cephalothin++ were used during operations for rectum cancer. The antibiotics were administered intravenously and immediately into the superior rectal artery. It provided high levels of the antibiotics in blood and discharge of the small pelvis cavity and prevented development of infectious complications during the postoperative period.

Bacterial Infections↗

[Pharmacokinetics of the antitumor antibiotic bleomycetin in cancer patients given the preparation by different methods].

The pharmacokinetics of bleomycetin, a new antitumor antibiotic prepared in the USSR, was studied microbiologically. The less the extent of the main tumor in the patients, the higher the antibiotic blood levels in them. This might be associated with the adsorption capacity of the tumor tissue. The dependence of the bleomycetin kinetics on the intensity of renal clearance was shown. The characteristics of the drug distribution in the blood after intravenous, intramuscular and intrapleural administration are presented.

Antibiotics, Antineoplastic↗