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Biomedical subjects

T A Vorob'eva

Publications and source records attributed to T A Vorob'eva.

8 recordsLinked to original sources

[Detection of the epithelial membrane antigen in patients with varying status of the gastric mucosa using monoclonal antibodies].

To study how the normal gastric mucosa develops chronic gastritis, gastric ulcer or cancer, biopsies from 103 patients with non-tumor gastric diseases and operative specimens from 12 patients with stomach carcinoma were examined for epithelial antigen (EA). In the peroxidase-antiperoxidase reaction performed on paraffin-embedded and cryostat sections of the gastric mucosa, monoclonal antibodies (MAb) to antigens located on the membranes of fatty breast milk globules were employed, which had been presented by the Department of Biomedical Sciences, Tampere University (Finland). The MAb 111C12-identified antigenic determinant was found to occur in 12.8% of the nonmalignant gastric mucosa examined and 48% of the stomach carcinoma one. The detection of EA is not characteristic of the given portion of the gastric mucosa in carcinoma.

Adenocarcinoma↗

[Reactions of humoral and cellular immunity in peptic ulcer in relation to the condition of the gastric mucosa].

A total of 160 persons including 50 patients with duodenal ulcer (DU) and 38 with gastric ulcer (GU) were examined for antibodies to the parietal cells of the stomach (PCA) and cell cellular immunity responses to autologous antigen from the gastric mucosa. It was shown that both PCA of the stomach and cell immunity responses in patients with GU and DU occurred in an insignificant number of cases. No differences were revealed in the humoral and cellular immunity in GU and DU persons with and without concomitant gastritis or in the stage of exacerbation and ulcer cicatrization.

Adult↗

[The role of emotional-motivational processes in the mechanism of "insight" in the recognition of a latent visual image].

The task of the study was to determine the influence of emotional-motivational sphere on the phenomenon of out-of-logic mental activity. An accepted in laboratory model of recognition of concealed image in double image pictures was used. The electrical activity, recorded was analyzed by means of the method of computation of coefficient of community, elaborated in the laboratory, the results were presented in the from of stereometric map. The obtained results testify to the fact that emotional-motivational processes influence the mechanism of out-of-logic form of making solution; at out-of-logic form of making solution subjective evaluation of results dominates, what is reflected in the character of spatial distribution of coefficient of community.

Adult↗

[The role of the extralogical form of thinking in cognitive activity].

The aim of the study was an attempt to record neurophysiological processes connected with the mechanism of subconscious brain activity. Created in the laboratory method of construction of a topographical map of electrical processes interactions in 24 recorded points was applied. The obtained data testify that identification of evident and latent images in "double image pictures" is accompanied by similar relief of topomaps of interactions. Effect of "sudden vision" of latent image in a manner of "insight" is gradually prepared neurophysiologically, but is not realized by the subject and only at the last stage reaches the consciousness and is verbalized.

Adolescent↗

[Systems organization of the electrical activity of the brain in recognizing a visual image based on data from the mapping of interconnection indices].

Eight subjects were studied by the method of topographic mapping of interconnection characteristics of the human brain electrical activity in the process of recognition of visual images. The method used in our studies differs from others by the fact that properties of the processes interconnections are mapped but not the characteristics of the very processes. Under recognition of images the relief of topographic map of interconnections of cortical electrical processes increases in the right and decreases in the left frontal areas. Thus both hemispheres participate in this process. The hypothesis is suggested about two types of spatial synchronization: of similar electrical activity and of the activity differentiated in the brain sections. The developed method proved to be informative for the studied structure of spatial-temporal organization of the human brain electrical activity.

Adolescent↗

[The mechanisms of uncognizable perception controlling human behavior].

The task of the study was to determine the influence of emotional-motivational sphere on the phenomenon of out-of-logic mental activity. An accepted in the laboratory model of the recognition of a hidden image double image pictures was used. Recorded multichannel EEG was analysed by the method of computation of coefficients of community elaborated in the laboratory. The results of computation were presented in a form of a stereometric map. The obtained results testify to the fact that the emotional-motivational processes influence the mechanism of the out-of-logic form of decision making. At the out-of-logic form of decision making a subjective evaluation of results dominates being reflected in the character of the spatial distribution of coefficient of community.

Adolescent↗

[The effect of set on human cognitive activity].

A psychological set was formed in 30 healthy adult subjects by means of successive exposition on the screen (with the intervals in 3-7 sec) of 30 single pseudo words written in the Latin letters. This series of stimuli was immediately followed by similar presentation of 36 single Russian words which consisted of the letters written in the same way as some characters of the Latin alphabet. At the beginning of the second train of stimuli all the subjects began to read the well-known Russian words as senseless. In 11 subjects this effect disappeared after 1-2 Russian word presentations and in 19 subjects only after 6-36 presentations. Analysis of the reaction time to the presentation of the visual probe stimulus suggests that the formation of preparatory set improves selective attention to the stimuli acting in a given situation and thus consolidates the cognitive processes.

Adult↗