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Biomedical subjects

T Adámek

Publications and source records attributed to T Adámek.

9 recordsLinked to original sources
PubMed2006

[Using of scanning electron microscopy for detection of gunshot residue].

Scanning electron microscope improves the possibility of investigation of surroundings near of gunshot wounds in forensic medicine, it is the next subsequent method for differentiating of area of entrance and exit wound, supplemental method for determination of firing distance, permit of detection (GSR) on the hand of shooter and ensured describing of samples and their stored. Detection of GSR provides many information about composition of bullet and primer. Authors are demonstrating the possibility of detection of GSR on experimental shooting to the krupon (pigs' skin) in different situation (such as in a room and in outside area) and using of different weapon (hand gun CZ No.75 and machine gun No.58).

Animals↗
PubMed2004

[Findings in bronchial lavage in patients with burns of the upper respiratory tract].

The study is focused on cytologic and biochemical changes in bronchoalveolar lavage (BAL) at the group of patients from the Clinic of Burns Medicine at the University Hospital Královské Vinohrady in Prague. Only patients with inhalation trauma were involved in the study. The obtained data are from BAL measurements collected between intubation and extubation. There was the greater number of polymorphonuclears in the first two weeks in all patients. After 2-3 weeks there was a gradual increase in the number of macrophages at four patients and three patients had still the greater number of polymorphonuclears. There was a positive findings of PCNA at one patient and other markers (bcl-2, p53) were negative. The cytoflowmetry proved the increase in number of CD3 cells by 20% in one patient. The amount of proteins in the last BAL just before extubation was lower than 22 g/l. Serin proteinase activity was lower than 50 ncat/l at five patients and the ratio of MMP-8/TIMP-2 was higher than one in all analysed samples. There was no development of lung inflammation into chronic stadium. Two patients died.

Adult↗
PubMed2004

Inhalation trauma in burns, cytology and biochemical findings.

We have followed in a pilot study a group of patients for cytological and biochemical changes of lavage in the upper and lower respiratory system. Into the study patients with respiratory burns confirmed by bronchoscopy and skiagraphy were included. We divided patients according to the Lung Injury Scores (LIS). We obtained the values in our sample group between intubation and last swab (before extubation). Listed are the risk factors, probability of survival, and lung histology results are listed for patients who died.

Aged↗
PubMed2002

[Findings in myocardial extracellular matrix in fatal poisoning with addictive substances].

It have been reported that chronic drug abuse induces changes in extracellular matrix (ECM) composition of myocardium. Matrix metaloproteinases (MMP) play important role in ECM remodelling and alteration in the ECM of myocardium. They are able to cleave ECM components and may contribute to progression of heart damage. Remodelling implies an alteration in the ECM and in the spatial orientation of cells and intercellular components. In this report we evaluated the extracellular matrix of myocardium of deceased drug abusers and controls. The myocardium of 5 toxicologically positive cases and 4 control cases were analysed by zymography of MMP, electrophoresis of collagens and histologicaly. Gelatinases (MMP-2 and MMP-9) and collagenase (MMP-1) activities were increased in drug abusers compare to the controls. In contrast, alpha chain of collagen type I after 160 hours collagen extraction, were not observed in control specimens. The activation of MMP proenzymes is one of the critical steps that lead to ECM breakdown. Our findings suggest that the myocardial collagen matrix is damaged in drug abusers.

Adolescent↗
PubMed2001

[Epidemiologic study of fatal injuries autopsied at the Institute of Forensic Medicine of the 3rd Medical School of Charles University Hospital in Vinohrady, Prague, from 1996 to 1999].

In our study comprising 1010 persons who died as a result of injury death at the age of 15-97 years and were autopsied in the Institute of Department of Forensic Medicine of the 3rd Faculty of Medicine and University Hospital Královské Vinohrady, were 748 men and 262 women. 717 died at the site of injury and 293 died from the consequences of the injury in hospital. The most frequent cause of injury death was unintentional deaths (56.14%), followed by suicide (26.83%), murder (12.48%) and occupational injuries (4.55%). Road traffic accidents accounted for 51% of unintentional injury deaths. The most frequent cause of death was traumatic shock (32.67%), followed by injuries of the brain and spinal cord (30.50%). Injuries affect most frequently the head (60.5%) and chest (56.9%). The presence of alcohol in blood was detected at 30.2% of deceased.

Adolescent↗
PubMed2001

[Objective evaluation of thoracic injuries and associated injuries using the Abbreviated Injury Scale and the New Injury Severity Score].

The authors focused attention on objectivization of the severity of chest injuries and associated injuries using the Abbreviated Injury Scale (AIS) and the New Injury Severity Score (NISS). They evaluated injuries detected on post-mortem examination in subjects who died from the sequelae of injuries in the Faculty Hospital Prague 10. The group comprised a total of 90 subjects regardless of sex aged 17-94 years who died in the hospital in 1996-2000. Traffic injuries accounted for 70% deaths, other blunt injuries for 27.8% and only 2.2% were penetrating injuries of the chest. The mean AIS value of the chest was 3.7, the mean value of NISS was 50.7. The NISS value declined in relation to age of the deceased patients and the period of survival. The period of survival varied from 30 mins. to 136 days. The mean NISS value on survival up to 5 hours after injury was 55.0. On comparison of our group we found that the results were consistent with those of American studies.

Abbreviated Injury Scale↗
PubMed1989

[Isolated aneurysm of the iliac artery as a source of postoperative peripheral embolism].

An isolated aneurysm of the iliac artery is a rare disease occurring 10 times less frequently than an aneurysm of the aorta. Aneurysms of the iliac artery are yet 10 times less frequent. The rare incidence of the condition is the cause why it is not taken into account in the differential diagnosis. Electively treated aneurysms have a minimal mortality and morbidity, while symptomatic aneurysms with subsequent complications due to haemorrhage, penetration or embolization calling for urgent surgery, have a mortality of cca 50%. In the patient described by the authors embolization and ischaemia of the lower extremity developed during the immediate postoperative period after prostatectomy. Only the peroperative finding explained the cause of the embolization.

Aged↗
PubMed1989

[Choledochocele diagnosed before surgery].

The authors describe the case of a 73 year old man with obstruction jaundice, who was examined before the operation by PTC with resulting diagnosis of choledochocoele connected with cholelithiasis. The preoperation diagnosis of this rare anomaly is not frequent and is due to the development of radiodiagnostic methods. A surgical solution is based either on discision or removal of the whole formation.

Aged↗