Blood pressure and correlations.
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Humans↗
Biomedical subjects
T Aitchison
Publications and source records attributed to T Aitchison.
Equine whole saliva: variability of some major constituents.
Whole saliva was collected from six horses over a period of five weeks in sufficient volume for the analysis of 10 constituents. There was considerable variation in the concentration of the analytes both between horses and between different days in the same horse. The most variable constituent was sodium, and the least variable was glucose, but this was derived from the sweet used to stimulate salivation. The use of whole saliva as a fluid for investigation would depend on achieving the minimum variability possible.
Animals↗
Severe sunburn and subsequent risk of primary cutaneous malignant melanoma in scotland.
A case-control study of occupational and recreational sun exposure, Mediterranean and other sun-exposed holidays, tanning history and history of isolated episodes of severe sunburn has been carried out on 113 patients with cutaneous malignant melanoma and 113 age- and sex-matched controls. Social class and skin type were also considered in the analysis of the data which involved the use of conditional multiple logistic regression. A highly significant increase in the history of severe sunburn was recorded in melanoma patients of both sexes in the 5-year period preceding presentation with their tumour. Higher social class and negative history of recreational sun exposure were also significantly increased in patients by comparison with controls. In the male group severe sunburn, lack of occupational sun exposure and higher social class were significant factors while in the female group only severe sunburn was significantly increased in the melanoma patients. This study thus provides evidence to suggest that short intense episodes of UV exposure resulting in burning may be one of the aetiological factors involved in subsequent development of melanoma.
Adolescent↗
Measurement of fundal height as a screening test for fetal growth retardation.
Fundal heights were measured on 761 women in the course of their routine antenatal care. This information was assessed, alone and in combination with other variables such as previous obstetric history and smoking, for its utility in predicting growth retardation. The results were disappointing. By most criteria used for classification, approximately half of the growth retarded babies were classified as such while half were missed. False positive rates were unacceptably high. It is concluded that fundal height measurement is of little use as a screening test for growth retardation.
False Positive Reactions↗
Screening for the small-for-dates fetus.
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Female↗
The value of diagnostic ultrasound as a screening test for intrauterine growth retardation: comparison of nine parameters.
In an attempt to devise a screening method for the detection of unsuspected IUGR, a battery of ultrasonic measurements of the fetus were performed in a series of 255 patients at approximately 32, 34, and 36 weeks. The results obtained from the 16 growth-retarded and the 239 normally grown babies were evaluated. While no single measurement was found to discriminate the two groups, a simple combination of crown-rump length times area of trunk allowed us to identify an at-risk group comprising 11 per cent of the population. The false positive and false negative results were acceptable at levels of 10 and 6 per cent, approximately. It is considered that these results would justify a larger and prospectively randomized controlled trial to assess the benefits and drawbacks of applying these measurements in a screening schedule.
False Negative Reactions↗