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Biomedical subjects

T Akizuki

Publications and source records attributed to T Akizuki.

At least 19 recordsLinked to original sources
PubMed1999

Histological examination of regenerated bone through craniofacial bone distraction in clinical studies.

The process of bone formation by distraction osteogenesis of the craniofacial bone has been studied in animals. To our knowledge there are no published findings in which histological examination of craniofacial distraction in humans has been reported. Specimens were obtained from 10 patients who underwent craniofacial distraction: 2 patients who underwent mandibular distraction, 7 patients who underwent midface distraction, and 1 patient who underwent nasal bone distraction. These specimens were examined histologically. The results revealed that 8 of 10 patients exhibited new bone formation. No cartilaginous callus formation was observed in any of the specimens, which strongly suggests that new bone was produced by intramembranous ossification during human craniofacial bone distraction.

Adolescent↗
PubMed1998

Avoiding ectropion by using the Mitek Anchor System for flap fixation to the facial bones.

The application of the Mitek Anchor System for bony fixation of the flap in the cheek area is described. The cervicofacial rotation-advancement flap is fixated to the malar bone using Mini Anchors for the purpose of diminishing the downward traction on the lower eyelid. They reduced the tension in the distal part of the flap and avoided distal-edge necrosis and ectropion. In another patient the free vascularized musculocutaneous flap, which had been grafted previously for a surgical defect in the cheek and resulted in ectropion of the lower eyelid, was fixated to the malar bone, and the ectropion was corrected. The Mitek Anchor System is useful in flap fixation to the bone because it provides a simple, fast, and reliable method for flap fixation with minimal dissection and precise placement.

Adolescent↗
PubMed1998

Vertical symphyseal osteotomy.

For the treatment of mild crossbite with increased bigonial distance, the authors performed a vertical symphyseal osteotomy on six patients in the last 3 years. Three of these patients had cleft lip deformities and the others had operations for orthodontic or aesthetic reasons. After exposing the mandible through the buccal mucosal incision, both premolars were extracted with or without conventional segmental osteotomy. The two vertical symphyseal osteotomies were performed with approximately 1 cm between them, and the central part of the mandibular bone was discarded. The bilateral segments of the mandibular body were fixed in the midline using titanium miniplates. Satisfactory results were obtained with a reduction in the size of the mandibular arch, which produced better three-dimensional proportions in the bimaxillary area. No patients had temporomandibular joint problems, however postoperative orthodontics were essential for this type of operation.

Adult↗
PubMed1997

Medical canthoplasty with the Mitek Anchor System.

A variety of surgical techniques have been described for medial canthal tendon reattachment. They generally require technical skill and prolonged operating time. We have applied a new device, the Mitek Anchor System, in reattaching the medial canthal tendon to the medial orbital wall in 3 patients, and got excellent tendon fixation with this rapid and simple method. No complications, such as local infection or exposure, have occurred in any of the patients up to the present. Medial canthoplasty using the Mitek Anchor System has the advantage of being an easy technique with very accurate placement of the anchor and, consequently, reduced operating time. The operation can be performed through a small incision as well, and may not be so invasive as with other conventional procedures. This new technique of medial canthoplasty offers an excellent alternative to conventional techniques.

Adult↗
PubMed1996

A thinned forearm flap transfer to the nose.

We employed a forearm flap that had been thinned through primary defatting for nasal covering in three cases to reduce the need for secondary revision. Partial flap loss did occur in one case due to subcutaneous vascular plexus injury, but acceptable results were obtained in the remaining two cases. Donor site concave deformities were substantially reduced by removal of fat from around the flap margin. Great care must be taken during surgery to avoid damage to the small vascular network around the pedicle to prevent flap necrosis.

Burns↗
PubMed1996

Combined use of an orbital osteotomy and living bone graft in the treatment of huge ossifying tumors involving the orbit.

Huge ossifying tumors involving the orbit were treated with a combination of craniofacial surgery and microsurgical techniques in two patients. The orbital osteotomy facilitated wide exposure of the tumors and their excision even though the tumors were extremely large. Stable results were obtained in one stage without visual disturbance by simultaneous reconstruction of the resulting bony defects using a free vascularized bone graft even in unfavorable tissue beds such as when one side of the bone graft is exposed to the affected nasal cavity or maxillary sinus. The combination of craniofacial surgery and microsurgical techniques has proven in our experience to be an effective approach to the treatment of a huge orbital ossifying tumor in one stage.

Adult↗
PubMed1995

Harvest of sural nerve grafts using the endoscope.

Endoscopic surgical techniques were employed in 5 patients to harvest the sural nerve atraumatically with a minimal number of skin incisions. The medial sural nerve was harvested by two 2-cm-wide transverse incisions made under endoscopic-magnified visualization, which allowed the surgeon to see the detailed structure of the nerve and surrounding tissue. This method requires minimal traction of the nerve during nerve dissection, and postoperative pain and swelling were less than encountered with conventional methods, because the method we have employed is less invasive and atraumatic.

Endoscopy↗
PubMed1993

Extremely thinned inferior rectus abdominis free flap.

To overcome a major drawback of the inferior rectus abdominis free flap, unpleasant thickness in a obese patient, a method of extreme thinning of the flap has been introduced. Extreme thinning is achieved by resecting a large volume of subcutaneous fatty tissue of the flap using scissors without damaging the subdermal vascular plexus. According to our clinical experience, it is supposed that the extremely thinned portion can be prepared safely when the width-to-length ratio is within 1:2.

Abdominal Muscles↗
PubMed1991

A long surviving case of holoprosencephaly agnathia series.

The rare syndrome of the agnathia with microstomia, aglossia, synotia (the external ears approaching one another in the midline) and brain malformation (agnathia-holoprosencephaly) was reported by Pauli et al. (1983) as a developmental field defect. This syndrome has two subgroups. One is more severe with brain malformation (holoprosencephaly), and the other is less severe without brain malformation. This report presents a long surviving case of this syndrome without brain malformation.

Body Height↗
PubMed1990

Microsurgical facial reconstruction of a xeroderma pigmentosum patient after skin tumor resection: case report.

Microsurgical reconstruction of the face completely destroyed after malignant skin tumor excisions in a xeroderma pigmentosum patient is reported. The patient's left cheek was reconstructed using a free latissimus dorsi flap and the nose using a free forearm flap with a base of iliac bone graft. There has been no recurrence of tumor at or surrounding the transferred flap site over two years postoperative follow-up.

Adult↗
PubMed1990

A histopathologic study of spinal cord ischemia using an isohistogenic rat upper-half-body transplantation model.

To study the histopathologic changes of spinal cords exposed to long-duration complete ischemia, the authors developed an upper-half-body transplantation model of inbred rat. In this model, an infant Lewis rat is transplanted to the inguinal region of another adult Lewis rat using microsurgical vascular anastomosis. Even when 2-week-old donor rats were exposed to complete ischemia for 90 minutes, functions of the spinal cord were comparatively preserved. In histopathologic observations, degeneration proportional to complete ischemia duration was noted. In the 60-minute ischemia group of 2-week-old donor rats, however, no substantial differences from normal spinal cord were observed. Under conditions of equal ischemia duration, it appeared the younger animal had the greater ischemic tolerance.

Animals↗