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Biomedical subjects

T Ametani

Publications and source records attributed to T Ametani.

At least 19 recordsLinked to original sources

[Pineal teratoma--case report (author's transl)].

A 3-year-old boy had a history of nausea and vomiting for 1 month. After two episodes of tonic cramp, he became drowsy and then semicomatous. Physical examination on admission revealed a dehydrated semicomatous boy with fixed, dilated pupils of equal size, horizontal nystagmus, and left hemiparesis with bilateral Babinski signs. Plain skull films showed a separation of coronal and sagittal sutures. A high density area surrounded by cyst was found in the pineal region in CT scan. Angiography demonstrated stretching of the posterior choroidal arteries, backward displacement of the Galen, the posterior mesencephalic and the precentral vein. The right occipital transtentorial approach was selected to remove the tumor totally. Histology revealed epidermis, hair follicle, sebaceus and sweat glands, columar gland, bone, cartilage, muscle, fatty tissue, nervous tissue, and connective tissue, indicating a pineal teratoma. There was no evidence of germinoma.

Brain Neoplasms↗

Nuclear characteristics of malignant lymphoma in the brain.

In addition to chromatin and nucleoli, various classes of structures were often seen in nuclei of malignant lymphoma, when compared with other brain tumours. Interchromatin, perichromatin, and atypical dense granules could be ribonucleoprotein in nature on basis of their behaviours in enzymatic extraction and EDTA stain. The perichromatin fibrils became visible at the border of the condensed chromatin only after EDTA stain and might contain substrate for HnRNA. Nuclear bodies and intranuclear fibrillar rodlets also were evident.

Brain Neoplasms↗

Fenestrae in golgi and endoplasmic reticulum cisternae of human brain tumours.

Fenestrae were found in freeze-fractured cisternae of the Golgi apparatus and endoplasmic reticulum of glioblastoma, oligodendroglioma, ependymoma, medulloblastoma, medulloepithelioma, meningioma, cerebellar sarcoma, hemangioblastoma, and chromophobe adenoma. They were about 200--400 A in diameter and often diffusely distributed or concentrated in groups in Golgi cisternae, while they were around 300--600 A in size and scattered in distribution in cisternae of endoplasmic reticulum. They appeared as conical protrusions or circular broken-off necks of face A and as circular holes on face B in tangential fractures, and as several constrictions of cisternae in cross fractures.

Adenoma, Chromophobe↗