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Biomedical subjects

T Amir

Publications and source records attributed to T Amir.

10 recordsLinked to original sources
PubMed2004

Follicular variant of papillary thyroid carcinoma -- a cytological study.

The cytological diagnosis of classical papillary carcinoma is easily established based on the characteristic architectural and nuclear features. However, the follicular variant of papillary thyroid carcinoma(FVPTC) poses a diagnostic challenge. In this study we analysed the cytological features of 14 histopathologically proven cases of FVPTC. We inferred that a combination of architectural features such as follicles and syncytial clusters and nuclear features, viz grooves, pseudoinclusions and enlarged nuclei with fine chromatin, were helpful in establishing the diagnosis. It is hence suggested that based on the combination of the aforesaid features a diagnosis of FVPTC be offered whenever it is possible. This helps in patient management, obviating the need for a second surgical intervention.

Biopsy, Fine-Needle↗
PubMed2000

Object concept and sleep regulation.

The association between infants' cognitive development and sleep regulation was investigated in 83 infants not at risk. It was found that 9-mo.-old infants with a more advanced object concept had significantly fewer sleep difficulties compared to infants with lower level of object permanence.

Anxiety, Separation↗
PubMed1998

Mast cell profile in prostatic lesions.

Mast cell profile in common prostatic lesions was analysed in this study. 17B consecutive prostatic biopsy specimens specimens were categorised broadly into nodular hyperplasia without prostatitis (101), nodular heperplasia with prostatitis (50, prostatic intraepithelial neoplasia (2) and adenocarcinoma (25). Toluidine blue stain (0.1%) was used to demonstrate the mast cells and their count was expressed per square millimeter. Mast cell count was significantly higher in the fibromuscular stroma when compared to the glandular areas in nodular hyperplasia (p < .05). The mast cell counts were very significantly lower in inflammatory lesions (p < 0.0001) probably due to degranulation. Absence or a low count was the most significant finding in adenocarcinoma irrespective of the grade of the tumour with concentration of mast cells around the tumour. This study shows the variations in mast cell distribution in commonly encountered prostatic lesions. There is paucity of such studies in the literature and the possible utility of mast cell count to differentiate malignant from benign and atypical conditions needs further evaluation.

Adult↗
PubMed1995

Pseudotumor cerebri in systemic lupus erythematosus.

OBJECTIVE: To assess the association between pseudotumor cerebri (PC) and systemic lupus erythematosus (SLE), and to seek a pathogenic mechanism that may elucidate the appearance of PC in patients with SLE. DATA SOURCE: Original English articles having the terms SLE, PC, or benign intracranial hypertension in their titles were identified by Medline search. In addition we report three new patients with this association. STUDY SYNTHESIS: Thirteen articles were found and 21 patients were analyzed. DATA EXTRACTION: Of the reported 21 patients, 18 were previously reported and 3 new patients with coexisting PC and SLE are described. The clinical characteristics of the patients is presented. Patients with PC and SLE generally had a more severe course of SLE; renal involvement occurred in 79%, massive proteinuria in 47%, and hematologic abnormalities were detected in a third. A hypercoagulable state manifest by either recurrent thromboembolic events or a high anti-cardiolipin antibody titer was detected in 58% of the patients described. CONCLUSIONS: The association of PC and SLE is probably not coincidental. The high prevalence of serologic or clinical evidence of a hypercoagulable state suggests that microscopical thromboembolic events play a role in the genesis of PC.

Adolescent↗
PubMed1994

Effect of hashish on vigilance performance.

A group of 11 hashish users were compared with 11 controls on a visual sustained attention (vigilance) task. Analysis indicated that hashish use affected subjects' sensitivity. Subjects who used hashish responded in an indiscriminate manner, making more false alarms (8.7) than controls (2.6). The importance of vigilance in the assessment of adverse effects of hashish is discussed.

Adult↗
PubMed1994

Effect of substance abuse on visuographic function.

The effect of substance abuse on visuographic functions was investigated by comparing 4 groups from an Arabian Gulf population: 63 heroin abusers, 14 alcohol abusers, 43 polydrug abusers, and 48 control subjects. The visuographic function was evaluated using Benton's Revised Visual Retention Test. Analysis of covariance yielded an over-all group effect on both number correct and errors. Assessment of significance of differences between groups showed that the polydrug-abusing group and the heroin-abusing group scored significantly lower than the nonabusing group on number correct. All 3 substance-abusing groups scored significantly higher than the non-abusing group on errors, which seems a better predictor of cognitive impairment. Classification of subjects on the basis of their scores on the Benton test showed that a significant proportion of subjects in each substance-abusing group were classified as impaired. It is concluded that the present findings were consistent with prior reports for European and American subjects.

Adult↗
PubMed1994

Personality study of alcohol, heroin, and polydrug abusers in an Arabian Gulf population.

Three male groups of heroin, alcohol, and polydrug abusers (n = 120) from an Arabian Gulf population were given Lanyon's Psychological Screening Inventory; their scores were compared with those of a group of 48 nonabusers. Only the polydrug-abusing group of 43 scored significantly higher than the nonabusers on the Alienation and Discomfort subscales. Perhaps only polydrug abuse can be explained in terms of attempts towards self-medication by distressed and inadequate individuals. A drug-accepting-generational age group in contrast to an alcohol-accepting-generational age group was suggested.

Adult↗
PubMed1991

Critical flicker frequency under monocular and binocular conditions.

Critical flicker frequency of 40 undergraduate students, 20 men and 20 women whose mean age was 19.3 yr., was measured under monocular and binocular viewing conditions, using the Lafayette Visual Perception Control with Display Unit. Half of the subjects received monocular treatment first and binocular treatment second, and the other half received the treatments in the reversed order. A 2-min. rest was allowed between these treatments. Analysis shows that mean CFF under the monocular condition was significantly lower than that under binocular conditions. The findings were discussed in terms of visual constraint and eye strain and fatigue under the monocular viewing condition.

Adult↗
PubMed1989

Effects of fasting on visual flicker fusion.

Two experiments are reported which investigated the effects of fasting on visual flicker fusion (VFF). In Exp. 1 the VFF of 40 undergraduate students, 20 men and 20 women, whose mean age was 22.5 yr., was measured in nonfasting conditions 1 to 2 weeks before and in fasting conditions during the Muslim fasting month of Ramadan. In Exp. 2 the VFF of a comparable group of 15 men and 15 women, whose mean age was 23.2 yr., was measured in a different month in both fasting and nonfasting conditions. Subjects were assigned randomly to these two conditions. Analysis shows that fasting reduced VFF significantly in both experiments. This finding indicates that fasting is likely to reduce perceptual sensitivity. The results were explained in terms of fatigue and physical exhaustion effects produced by fasting.

Adult↗