PubMed Health⌕ Search

Biomedical subjects

T B Baltabaev

Publications and source records attributed to T B Baltabaev.

14 recordsLinked to original sources

[Functional features of acute non-Q-wave myocardial infarction and the influence of pre-hospital treatment with propranalol, heparin and aspirin on the prognosis of the disease].

193 patients with their first non-Q-wave myocardial infarction (NQMI) were examined with the aim of studying the functional features of NQMI and estimate the influence of pre-hospital treatment with propranalol (PP), heparin and aspirin. The study found that patients having NQMI with initial ST segment depression, unlike those with initial ST segment elevation, were characterized by diffuse coronary atherosclerosis, evident diastolic dysfunction and left ventricle (LV) remodeling, progressing with the course of time. Early administration of aspirin, heparin and PP reduced LV remodeling, improved diastolic function and prognosis in patients having NQMI with initial ST segment depression.

Adrenergic beta-Antagonists↗

[Clinical experience using streptodecase in the prehospital stage of treatment of acute myocardial infarct].

The effects of prehospital streptodecase administration on clinical course, pattern of necrosis formation, myocardial contractility and blood coagulation were studied in 15 patients with acute myocardial infarction. Patients to whom thrombolytic and anticoagulant therapy was contraindicated made up the control group. A single intravenous jet injection of the total streptodecase dose (3,000,000 U) is well tolerated by patients with acute myocardial infarction without preliminary testing. Prehospital use of the drug contributes to rapid stabilization and limitation of progressive myocardial necrosis, and improves thereby the clinical course of the disease.

Acute Disease↗

[Atrial electrocardiotopogram in acute myocardial infarct complicated by heart failure].

Atrial electrocardiotopography is shown to be a fairly informative non-invasive method for both the detection of heart failure and the assessment of its severity. Its findings were verified by conventional invasive and non-invasive procedures. Moderate left-ventricular heart failure was only associated with increased total left-atrial electrical activity, while marked heart failure also involved an expanded negative P wave projection zone and a greater total magnitude of right-atrial potentials.

Adult↗

[Automated mapping of the heart electrical potentials in myocardial infarct patients].

A method is developed for automated cartography of the heart's electric potentials from 90 points on the chest surface. The input data program determines characteristic QRS profiles on the basis of change in the value of the first derivative, labelling the identifiable characteristic outlines, computes the gradients for Q/R, R/S amplitude ratios for every element of the field and estimates zone area for each gradient and mean Q, R, S wave amplitudes for all points within the field.

Electrocardiography↗

[Use of nitroglycerin in acute myocardial infarct complicated by mitral insufficiency].

Thirty-five patients with primary large-focal myocardial infarction (MI) were investigated, with mitral incompetence diagnosed in 19. All patients underwent clinical investigation, including electro-, phono- and echocardiography, and tetrapolar chest rheoplethysmography. Direct measurements of pulmonary arterial pressure were made in 11 patients. The investigations were carried out prior to, and at the peak of nitroglycerin action. It was shown that mitral regurgitation was associated with increased incidence and severity of heart failure during the acute stage of MI. Such patients showed low cardiac and stroke index values, a more marked overstrain of the left atrium and left ventricle, and high pulmonary arterial pressure. Intravenous administration of nitroglycerin improves intracardiac hemodynamics in acute MI, its effect being more pronounced in patients with mitral incompetence. Early and prolonged nitroglycerin treatment is indicated in cases of acute MI with mitral incompetence.

Adult↗

[Evaluation of the reserve capacity of the heart in acute myocardial infarct by creating a brief volume load].

A combination of non-invasive and invasive procedures was used to assess hemodynamic response to negative pressure applied to the lower parts of the body (NPLB) in 56 patients with acute myocardial infarction and varying degrees of heart failure (HF) and 20 normal subjects. Normal subjects and HF-free patients showed a significant decrease in their stroke and cardiac indices and pulse pressure, and a rise in specific peripheral resistance, while the HF patients demonstrated higher cardiac productivity and lower specific peripheral resistance. Within 3 minutes after the discontinuation of NPLB, part of the depot blood returned to the central channel, creating a volumetric load on the heart. In this situation, the pump function of the heart was activated in normal subjects and HF-free patients, while patients with latent HF showed no such response, and those with obvious HF demonstrated impaired pump function.

Acute Disease↗