Evaluation of the state of the circulatory system in the officers of the Polish ocean lines. Part IV. Subperiods of the left heart-ventricle systole.
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Biomedical subjects
Publications and source records attributed to T Banaszkiewicz.
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The results of the physical analysis of circulation presented in this report are a further fragment of our research on the state of the circulatory system in the merchant marine officers over 40. 307 men were selected at random for the examinations, this constituting 13.5 per cent of the total population of the officers employed by the shipowner. Altogether the examinations covered 118 deck officers, 152 engine-room officers and 37 officers of the catering department. The parameters of the physical analysis of circulation were calculated according to Broemser-Ranke. The mean value of pulse wave velocity at the aorta was 833.63 +/- 155.41 cm/sec and in the radial artery--891.93 +/- 124.91 cm/sec for the whole examined population. The mean deformation resistance for all the examined was 1349.02 +/- 248.68 dyne/cm and the circumferential resistance--1347.55 +/- 347.89 sec. dyne/cm3. The mean systolic discharge for all the examined was 82.68 +/- 18.66 ml and the minute stroke volume 6.64 +/- 1.92 l/min. The mean work of the heart 1.20 +/- 0.38 J, the heart's power--1.60 +/- 0.59 W. The velocity of the discharge from the left ventricle was on average 17.66 +/- 3.44 l/min. For those parameters no statistically significant differences were found between particular groups of employment aboard. However, statistically significant differences were discovered in the calculations of the pulse wave velocity at the aorta. The differences were noticed between the group of clinically healthy men (771.52 +/- 114.71 cm/sec) on the one hand and the overweight group (854.39 +/- 116.34 cm/sec), the obese group (900.13 +/- 155.08 cm/sec), the group with ECG changes (925.01 +/- 193.24 cm/sec), the group with systolic and diastolic hypertension (acc to WHO criteria) (997.16 +/- 177.82 cm/sec), and in the group with hypertension accompanied by systolic discharge murmurs above the aorta (1113.38 +/- 127.24 cm/sec)--on the other. The pathological pulse wave velocity in the aorta (i.e. velocity of at least 9 m/sec) was found in 22.47% of the whole examined population.
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Experimental studies were performed on healthy, 80-100 g carp (Cyprinus carpio). Fish were exposed by emersion in Roundup (205 mg of glyphosate/l or 410 mg of glyphosate/l) in concentrations of 40- to 20-fold lower than those used in practice. Electron microscopy revealed that the herbicide caused appearance of myelin-like structures in carp hepatocytes, swelling of mitochondria and disappearance of internal membrane of mitochondria in carp at both exposure concentrations. It means that Roundup was harmful to carp when used in applied concentrations. Results of these studies enhance our knowledge of ultrastructural pathomorphology of fish organs following exposure to Roundup.