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Biomedical subjects

T Banerjee

Publications and source records attributed to T Banerjee.

At least 19 recordsLinked to original sources
PubMed1995

Recent infection as a risk factor for cerebrovascular ischemia.

BACKGROUND AND PURPOSE: Previous infection is discussed as a risk factor for ischemic stroke in children and younger adults. We tested the hypothesis that the role of recent infection in cerebrovascular ischemia is not restricted to younger patients and investigated which infections are mainly relevant in this respect. METHODS: We performed a case-control study with 197 patients aged 18 to 80 years with acute cerebrovascular ischemia and 197 randomly selected control subjects matched for sex, age, and area of residence. RESULTS: Infection within 1 week before ictus or examination was significantly more common among patients (38 of 197) than control subjects (10 of 197; odds ratio [OR], 4.5; 95% confidence interval [CI], 2.1 to 9.7). Patients more often had febrile and subfebrile infections (> or = 37.5 degrees C) than control subjects (29 of 197 versus 5 of 197; OR, 7.0; 95% CI, 2.5 to 20). Respiratory tract infections were most common in both groups. Bacterial infections dominated among patients but not among control subjects. Infection increased the risk for cerebrovascular ischemia in all age groups; this reached significance for patients aged 51 to 60 and 61 to 70 years. The profile of vascular risk factors was similar in patients with and patients without previous infection. Infection remained a significant risk factor when previous stroke, hypertension, diabetes mellitus, coronary heart disease, and current smoking were included as covariates in a logistic model (OR, 4.6; 95% CI, 1.9 to 11.3). CONCLUSIONS: Recent infection, primarily of bacterial origin, may be a risk factor for cerebrovascular ischemia in older as well as younger patients.

Adolescent↗
PubMed1995

Clinical and biochemical analysis in infection-associated stroke.

BACKGROUND AND PURPOSE: Currently, recent infection (primarily bacterial infection) is discussed as a risk factor for cerebrovascular ischemia. The aim of this study was to investigate whether the association of ischemic stroke with recent infection is restricted to stroke subtypes and whether recent infection influences the severity of the postischemic deficit; we also aimed to define biochemical pathways linking infection and ischemic stroke. METHODS: Analyzing the data of a prospective case-control study, we classified the etiology of cerebrovascular ischemia on the basis of clinical, neuroradiological, sonographical, cardiological, and biochemical data in 159 patients without and in 38 patients with infection within 1 week before ischemia. We assessed the severity of neurological deficits using the Scandinavian Stroke Scale. RESULTS: In patients with recent infection compared with patients without infection, the neurological deficit on admission was more severe (median of scores, 41 versus 30.5; P < .005), cortical infarcts in the middle cerebral artery territory were more frequent (60% versus 26%; P < .001), the prevalence of extracranial artery stenoses was lower (9% versus 26%; P < .05), and definite or presumed cardioembolic stroke was more frequent (34% versus 19%; P < .05), as was stroke from cervical artery dissection (8% versus 1.3%; P = .05). Serum levels of C-reactive protein were higher in patients with (20.7 +/- 26.8 mg/L) than in those without infection (9.2 +/- 23.7 mg/L; P < .01). CONCLUSIONS: Recent infection may be associated with a more severe postischemic deficit and with an increased risk of stroke from cardioembolic origin and from cervical arterial dissection.

Adolescent↗
PubMed1991

Effect of 'Pan Masala' on the germ cells of male mice.

Cytogenetic analyses of meiotic metaphase I germ cells and abnormalities of head morphology of caudal sperms were conducted in male mice following oral feeding of Pan Masala. The substance was ground to a fine powder, dispersed in polysorbate solution and administered via gavage to the animals at 84, 420 and 840 mg/kg body weight at the rate of 10 ml/kg body weight. Polysorbate and cyclophosphamide served as the vehicle control and positive control respectively. The two higher doses, 420 and 840 mg, gave a significant increase in the frequency of X-Y univalents and breaks over those of the vehicle control. Frequency of sperm head abnormalities were significantly high for all the doses tested. The results indicate that Pan Masala is a potent clastogen, reaches the testes and affects the germinal cells.

Administration, Oral↗
PubMed1991

Structure of 4-(3-chlorophenyl)thiosemicarbazide.

C7H8ClN3S, Mr = 201.67, monoclinic, P21/c, a = 6.914 (5), b = 4.304 (4), c = 30.306 (3) A, beta = 94.66 (3) degrees, V = 899.0 (1) A3, Z = 4, Dm = 1.54, Dx = 1.490 Mg m-3, lambda (Cu K alpha) = 1.5418 A, mu = 5.54 mm-1, F(000) = 416, T = 298 K, final R = 0.048 for 1219 observed reflections. The S and terminal hydrazinic N atoms are in a trans conformation. As a result of the sigma-electron-withdrawing effect of the Cl atom at the meta position in the phenyl ring with respect to the thiosemicarbazide chain, the net negative charge on the terminal N atom decreases compared to the p-chloro and p-methoxy derivatives. The antibacterial activity of the compound is also lowered.

Chemical Phenomena↗
PubMed1988

Structure of salicylaldehyde thiosemicarbazone.

C8H9N3OS, monoclinic, C2/c, a = 14.206 (3), b = 14.244 (4), c = 10.457 (4) A, beta = 116.18(2) degrees, V = 1898.9 (8) A3, Z = 8, Dm = 1.387, D chi = 1.366 g cm-3, lambda(Mo K alpha) = 0.71069 A, mu = 2.90 cm-1, F(000) = 816.0, T = 298 K, final R = 0.0429 for 1322 observed reflections. The S and hydrazinic N atoms lie trans. The lowering of antibacterial activity compared to that of 4-phenylthiosemicarbazide may be correlated with the decrease in negative charge on the hydrazinic N atom. The crystal structure is stabilized by hydrogen bonding, stacking interactions and van der Waals forces.

Aldehydes↗
PubMed1977

Nonhealing myelomeningecele in an adult.

A case of myelomeningocele in a 20-year-old woman is presented. The partially healed scar continued to produce infected debris despite vigorous local therapy. She died because of eventual local and retroperitoneal invasion of squamous cell carcinoma. The possible benefits of decisive planning are discussed.

Adult↗
PubMed1977

Intracranial epidermoid tumor: discussion of four cases.

Four cases of intracranial epidermoid tumor are presented. These are uncommon tumors with no specific signs or symptoms, and their diagnosis depends upon a high index of suspicion. Computerized axial tomography (CAT scan) was helpful in diagnosing one of the cases described and undoubtedly will be instrumental in identifying future cases. Epidermoid tumors are biologically benign. They are often amenable to resection, and therefore tissue diagnosis before starting any therapy is important.

Adult↗
PubMed1977

Review of 18 years' experience with pituitary tumors.

The presenting signs, symptoms, roentgenographic findings, endocrine evaluations, treatment, and results in 68 cases of presumed pituitary adenomas treated over an 18-year period are discussed. The most common symptoms were headache, acromegalic changes, visual symptoms, and amenorrhea. Most common physical findings were obesity, acromegaly, and visual field defects, usually bitemporal hemianopsia. Roentgenographic evidence of sellar erosion was almost universal but angiography and pneumoencephalography were required to evaluate suprasellar extension. Brain scan was not considered a particularly useful diagnostic tool. Endocrine status was best evaluated by a battery of tests including 17-OH, 17-KS, T3, T4, PBI, ACTH stimulation, and FSH and STH levels. (Prolactin levels are currently being obtained, also). Surgical specimens were obtained in 29 patients, with subsequent diagnoses of 22 chromophobe adenomas, five eosinophilie adenomas, one cystic adenoma, and one necrotic tumor. All five eosinophilic tumors came from acromegalic patients. Patients treated by operation alone or operation followed by radiotherapy generally had less "medical morbidity" than did patients who received radiotherapy alone.

17-Hydroxycorticosteroids↗
PubMed1977

Abnormal movements with hydrocephalus. Case report.

The author reports the case of a pituitary dwarf with choreoathetoid movement of the tongue and both arms as results of a shunt malfunction. He had undergone craniotomy for excision of a suprasellar craniopharyngioma, and 13 years later complete cerebral angiography and Conray ventriculography showed massive hydrocephalus with no evidence of tumor recurrence. Revision of the shunt was followed by complete recovery of the movement disorder.

Adult↗
PubMed1976

Carpal tunnel syndrome: discussion of operating technics.

A case of carpal tunnel syndrome's is presented. Histologic examination of the volar carpal ligament showed fibrocartilaginous changes suggesting a progressive degenerative phenomenon. Operative intervention relieved the pain and disability. It is implied that biopsy of the carpal ligament and/or the synovial sheath often will be helpful in making a complete diagnosis. The results of this simple operating technic are contrasted with other procedures.

Carpal Tunnel Syndrome↗
PubMed1976

Sciatic entrapment neuropathy. Case report.

A case of sciatic entrapment neuropathy is discussed. When evaluating patients with unilateral leg pain and paresthesias, one should consider the possibility of entrapment of peripheral nerve. Electrodiagnostic studies are helpful in establishing the diagnosis.

Adult↗
PubMed1976

Oblique muscle splitting incision for cervical laminotomy.

A muscle-splitting incision for cervical disc disease is described. It is based upon sound surgical principles. There have been no wound complications in the last 60 patients treated by the authors. Its most stringent demand is that the surgeon be familiar with the anatomical planes to be certain of the level which he wishes to explore.

Cervical Vertebrae↗