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Biomedical subjects

T Bergendal

Publications and source records attributed to T Bergendal.

27 records · Page 2Linked to original sources

A combined clinical, mycological and histological study of denture stomatitis.

The clinical and histological appearance of the different types of denture stomatitis are in many respects very similar and confluent. In order to study the correlation between clinical and histological appearance and amount of yeasts, 48 patients with denture stomatitis and 24 with a healthy palatal mucosa were examined. The terms atrophic and hyperplastic denture stomatitis were introduced. The intensity of the palatal erythema and the growth of yeasts were most prominent among patients with hyperplastic lesions. Dryness and soreness of the mouth, angular cheilitis, spontaneous hemorrhage, glossitis and leukoplakias were found to a varying extent. No statistical evidence of correlation between the intensity of clinical erythema, amount of yeasts and grade of subepithelial inflammation could be found. The disease has most certainly a background other than solely increased growth of yeasts.

Adult↗

Status and treatment of denture stomatitis patients: a 1-year follow-up study.

The material comprised 48 patients, 19 exhibiting atrophic and 29 hyperplastic denture stomatitis. Twenty-seven patients with healthy mucosa served as a reference group. Past history, resilience of the mucosa, denture function and scores of palatal erythema, plaque and yeasts were recorded. The therapeutic program included new dentures, surgical and nystatin treatment, hygienic instruction and nutritional advice. The result concerning past history showed significantly more smokers, more patients with recurrent urinary tract infections in combination with prolonged antibiotic therapy, and more patients wearing their dentures at night in the denture stomatitis group. Nystatin treatment did not affect the healing of palatal erythema evaluated after 1 year. The treatment program evaluated after 1 year resulted in complete healing of the mucosa in 50% of patients. The remaining 50% had persisting erythema of varying intensity. The unhealed cases showed significantly more yeasts and plaque on the denture bas compared to the healed patients and the reference group. An evaluation of factors common to failure of healing is presented.

Adult↗

Studies of Candida serology in denture stomatitis patients.

The aim of the study was to determine the humoral antibody response to Candida by means of hemagglutinin and precipitin tests and to correlate these results to yeast colonization in the oral sites and feces and to the relapse tendency after treatment; and furthermore, to evaluate whether Candida serology can serve as a tool to predict a denture stomatitis risk group. The serologic tests were performed by means of passive hemagglutination (HA) and immunoelectroosmophoresis (counterimmunoelectrophoresis, CIE) tests in 51 denture stomatitis patients and compared with 25 individuals in the reference group. There were significantly more patients with increased hemagglutinin titers (pos. greater than or equal to 1:160) to Candida albicans polysaccharide (mannan) antigen and/or precipitin to crude C. albicans cytoplasmic antigen in serum (P less than 0.01) than in the reference group. In the denture stomatitis group there was no correlation between the presence of hemagglutinating and precipitating Candida antibody in serum and the parameters yeast colonization of the oral sites/feces, yeast score on the denture base and palatal erythema score. After local oral antimycotic treatment there was no significant change in the serum Candida hemagglutinin titers and serum precipitins. Serologic tests might be useful as a guidance in a selected group of patients for continued prosthetic treatment and as a prognostic instrument.

Adult↗

Surgery in the treatment of denture-related inflammatory papillary hyperplasia of the plate.

Twenty patients with denture-related papillary hyperplasia of the palate were surgically treated after careful instruction in oral and denture hygiene, insertion of new dentures and nutritional information. A tissue conditioner was used to cause detumescence of the palatal mucosa presurgically and to act as a wound dressing postsurgically. A knife with a semicircular blade made it possible to cut and plane off the papillary hyperplasia in all regions of the palate and accurately to control and vary the thickness of the extirpated tissue. The advantages of this gentle planning surgery were a short healing time (mean 12 days), no bleeding and no pain that necessitated the use of analgetics. After surgery a persistent erythema of the palatal mucosa appeared in five patients. Such a low rate of postsurgical erythema has not previously been reported. A microscopic examination of the extirpated tissue was performed and the findings are discussed.

Adult↗

Effect of nystatin in the treatment of denture stomatitis.

The effect of nystatin treatment on denture stomatitis subclassified as generalized simple inflammation and inflammatory papillary hyperplasia has been studied. Twenty-four patients were carefully instructed to apply a thin layer of nystatin dusting powder on the fitting surface of the maxillary denture three times a day for 14 d. Different parameters were studied on three occasions; at the beginning of experiment and after 14 and 28 d. An untreated group of 24 patients with the same types of denture stomatitis served as control. The effect of treatment was evaluated by changes in the clinical erythema, the yeast colonization obtained by mycologic sampling on the palatal mucosa and on the denture base, and changes in the histologic picture of the mucosa obtained by biopsy. Subepithelial inflammation, leukocyte penetration, edema and thickness of the epithelium were histologic parameters. After 14 d of treatment the experimental group compared with the control group showed a statistically significant decrease in palatal erythema and in the amount of yeast colonies. No significant changes were found microscopically. Twenty-eight days after start, i.e. 14 d after withdrawal of the nystatin, there still was a statistically significant improvement of the palatal erythema in the experimental group compared with the controls. However, no patient was totally cured. There were no significant changes in the number of yeast colonies and the histologic parameters.

Aged↗

Laser-welded titanium frameworks supported by implants in the edentulous maxilla: a 2-year prospective multicenter study.

PURPOSE: The aim of this study was to evaluate the clinical and radiographic performance of patients who received implants and fixed prostheses with laser-welded titanium frameworks. MATERIALS AND METHODS: Fifty-eight consecutive patients were treated with 349 osseointegrated implants ad modum Brånemark in the edentulous maxilla at 6 implant centers. The patients were randomly arranged into 2 groups at the time of final impression. Twenty-eight patients received laser-welded titanium frameworks and 30 patients received conventional cast frameworks. Clinical and radiographic data were collected for 2 years in function. RESULTS: The 2 groups of patients showed similar results. The 2-year overall cumulative implant survival rate from the time of implant placement and prosthesis insertion was 93.7% and 96.2%, respectively. The corresponding cumulative survival rate for prostheses was 96.6%. Two patients, 1 from each group, failed completely and resumed using conventional complete dentures. The only obvious factor that could possibly be related to the 2 complete failures was a smoking habit. However, it was not possible to significantly correlate implant failures to smoking habits in this study. No fractures were observed in the frameworks or implant components, and both groups experienced the same frequency of resin veneering material fractures. The overall average marginal bone loss was 0.4 mm (SD 0.8 mm). CONCLUSION: Patients treated with implant-supported prostheses fabricated with laser-welded titanium frameworks in the edentulous maxilla presented comparable results to patients with conventional cast frameworks after 2 years in function.

Adult↗

Changes in signs and symptoms of temporomandibular disorders following treatment with implant-supported fixed prostheses: a prospective 3-year follow up.

PURPOSE: The aim was to investigate whether the replacement of lost teeth with implant-supported fixed prostheses (IFP) had any influence upon the signs and symptoms of temporomandibular disorders (TMD). MATERIALS AND METHODS: The subjects comprised 78 consecutive patients referred to a specialist clinic for treatment with IFPs. All were examined with respect to the presence of signs and symptoms of TMD before the start of treatment and after 1 and 3 years. RESULTS: Before treatment began, 21% of the patients were found to have moderate (15%) or severe (5%) clinical signs of dysfunction according to the Helkimo index. These figures decreased numerically but not statistically significantly to 10% and 1%, respectively, at the 3-year follow up. Nearly half of the patients (45%) reported one or more subjective symptoms of TMD at the first examination. The anamnestic index used had decreased statistically significantly at the 3-year follow up, when the 5 variables composing the index had improved, but the improvement was statistically significant only for the variables joint sounds and pain when opening the mouth wide. All patients were satisfied with the treatment received. CONCLUSION: The results from the present investigation show that treatment with IFPs has a good and lasting effect on the functional status of the masticatory system as well as on subjective symptoms of TMD and chewing ability in the vast majority of patients treated.

Aged↗

Implant-supported overdentures: a longitudinal prospective study.

The aim of this study was to evaluate the clinical function and long-term prognosis of overdentures retained by a small number of implants in the maxilla and mandible using one of two different attachment systems. Included in the study were all patients referred to specialty clinics in Jönköping and Linköping, Sweden, during the treatment period who needed an overdenture and could be provided with a minimum number of two bilaterally-placed implants. Excluded were patients with bone-grafted jaws, irradiated cancer patients, heavy bruxers, and patients who had lost a fixed prosthesis because of implant losses. The patients were randomly assigned to receive one retentive system, either a round 2-mm-diameter bar with clips or ball attachments (Nobel Biocare). Eighteen overdentures were placed in maxillae and 32 in mandibles, supported by a total of 115 Brånemark implants. Of the implants placed, 86.1% were continuously osseointegrated. The cumulative implant survival rates after 7 years of loading were 75.4% in the maxillae and 100% in the mandibles. There was no difference in implant survival rate between the attachment systems. Patients with implant losses were characterized by severely resorbed maxillary ridges and inferior bone quality, together with unfavorable loading circumstances such as short implants combined with long leverages. Complications and prosthetic adjustments were mostly resolved early and easily.

Adolescent↗