Biomedical subjects

T C Low

Publications and source records attributed to T C Low.

10 recordsLinked to original sources

PubMed2002

Severe pulmonary hypertension in a patient with bronchiectasis complicated by cor pulmonale and a right-to-left shunt presenting for surgery.

A patient with advanced bronchiectasis, severe pulmonary hypertension complicated by cor pulmonale and a right-to-left shunt at atrial level presented for sigmoid colectomy. We outline the potential perioperative problems of this situation, discuss the perioperative risks and describe our clinical approach. A total intravenous anaesthetic technique using midazolam, fentanyl, ketamine and rocuronium was used to minimize changes in pulmonary and systemic vascular resistance and not induce bronchospasm. Preoperative nebulized salbutamol and ipratroprium were given to prevent bronchospasm and adrenaline and noradrenaline were infused to maintain cardiac output and the balance between systemic and pulmonary vascular resistance.

Anesthesia, Intravenous↗

PubMed2002

Peripheral nerve blocks for lower limb surgery--a choice anaesthetic technique for patients with a recent myocardial infarction?

Peripheral nerve blocks are associated with minimal haemodynamic disturbance. It is perhaps ideal for high-risk surgical patients who cannot tolerate the adverse consequences of even the slightest attenuation of haemodynamic response. However, peripheral nerve blockade is often perceived to be time consuming and undependable as the sole anaesthetic. In this report, a 56-year-old man with severe sepsis and recent myocardial infarction presents for an urgent above knee amputation. We present the practical benefits of a combined sciatic-femoral nerve block on such a patient.

Amputation, Surgical↗

PubMed2000

A case report of the use of magnesium sulphate during anaesthesia in a patient who had adrenalectomy for phaeochromocytoma.

INTRODUCTION: Patients with phaeochromocytoma have haemodynamic instability during adrenalectomy. CLINICAL PICTURE: A case showing major swings of blood pressure during tumour handling. TREATMENT: Magnesium sulphate infusion alone failed to prevent severe hypertension. OUTCOME: The patient had to be given phentolamine and sodium nitroprusside to control the severe hypertension. CONCLUSION: The greatest value of magnesium sulphate is in controlling catecholamine release at induction and intubation, and in association with other agents in controlling arrhythmias and hypertension during tumour handling.

Adrenal Gland Neoplasms↗

PubMed1998

Sudden profound hypoxaemia in the intensive care unit--a case report.

Acute hypoxaemia is a life-threatening emergency. Diagnosis of the exact aetiology maybe complicated by the presence of pre-existing lung conditions. A case report is presented of a non-intubated patient with a pre-existing lung tumour who developed sudden profound hypoxaemia 3 days after emergency abdominal surgery. Definitive aetiological diagnosis was delayed due to chest X-ray features suggestive of compression and erosion of tumour tissue into the airway. Emergency computerised tomography (CT) imaging however revealed mucous plugging leading to massive atelectasis as the main aetiology.

Carcinoma↗

PubMed1997

Perioperative transfusion strategies: a national survey among anaesthetists.

A current concern in perioperative transfusion therapy is the balance between maintaining adequate haemoglobin level and yet avoiding unnecessary homologous blood transfusion. Strategies to minimise the perioperative use of homologous blood include redefining the traditional transfusion trigger of "10/30 rule", and the use of autologous transfusion therapy. Current recommendations for transfusion triggers advocate determining the "minimum acceptable haemoglobin level" for patients according to various other physiological or surgical factors. The current status of practice amongst anaesthetists in the above mentioned transfusion strategies was assessed using a national survey. An overall response rate of 59.4% was obtained. Results showed wide variation among respondents in their criteria used for preoperative and intraoperative transfusion. Recommendations on perioperative transfusion triggers made by various authors were also summarised. Autologous transfusion therapy was also not frequently practised-the reasons for this were identified. We concluded that in order to continually improve on the anaesthetic community's quality of perioperative care, continued education on the subject must be carried out. Certain practical issues also need to be addressed to facilitate the use of perioperative autologous transfusion therapy.

Anesthesia↗

PubMed1997

Preoperative versus postoperative pethidine for extraction of impacted third molars.

We have studied the pre-emptive analgesic effects of pethidine by comparing its analgesic effects given before or immediately after operation in a randomized, double-blind study of 40 patients undergoing removal of bilateral impacted third molars under general anaesthesia. Group 1 patients received pethidine 50 mg as a 1 ml injection 1 to 2 hours before operation and normal saline 1 ml intramuscularly immediately after surgery. Group 2 patients received normal saline 1 ml intramuscularly before operation and pethidine 50 mg as a 1 ml injection immediately after surgery. Outcome measures included perception of pain on a visual analogue scale (VAS), the number of patients who required postoperative pethidine, time to first postoperative pethidine injection and total dose of pethidine given. Four patients in group 1 compared to 8 in group 2 required postoperative pethidine but this was not statistically significant. The VAS scores, time to first postoperative pethidine injection and total dose of pethidine also did not differ significantly between the 2 groups. We concluded that preoperative administration of pethidine intramuscularly did not confer additional analgesic effects compared with a similar dose given after surgery.

Adult↗

PubMed1995

Propofol and postanaesthetic shivering.

Sixty ASA grade 1 unpremedicated patients scheduled for minor elective surgery were randomly allocated to receive general anaesthesia consisting of either propofol-nitrous oxide in oxygen or a conventional technique of thiopentone-isoflurane-nitrous oxide-oxygen. Baseline axillary temperature readings, duration of operation and intra-operative decrease in axillary temperature were similar in both groups. The patients who received propofol-nitrous oxide-oxygen anaesthesia had a significantly lower incidence of postanaesthetic shivering than the control group. A propofol-nitrous oxide-oxygen technique may be preferable when postanaesthetic shivering is deemed undesirable.

Adolescent↗

PubMed1992

Total intravenous anaesthesia versus inhalational anaesthesia for dental day surgery.

Fifty young healthy and unpremedicated patients scheduled for removal of impacted teeth were randomly allocated to receive either total intravenous anaesthesia with propofol or conventional thiopentone/isoflurane/nitrous oxide anaesthesia. A double-blind postoperative assessment showed the former group to have a shorter reversal time and faster recovery of faculties, i.e. speech, memory as well as ability to sit up and walk without assistance (P < 0.01). There was no incidence of hypotension and of awareness in either group. The incidence of headache, nausea and vomiting was higher in the thiopentone/isoflurane/nitrous oxide group.

Adolescent↗

PubMed1991

Is sedation without desaturation possible?

The correlation between the depth of sedation and the degree of oxygen desaturation was studied in 52 patients presenting for surgery under regional anaesthesia. After establishing successful regional anaesthesia, patients were sedated with incremental doses of intravenous midazolam. The various levels of sedation were scored from 0 to IV. Continuous pulse oximetry allowed for correlation of sedation and saturation. Each patient's presedation oxygen saturation served as the control value. This was compared with the saturation at sedation levels II, III and IV and was found to be significantly higher (p less than 0.001). There was also a significant drop in saturation as patients progressed from sedation level II to III (p less than 0.02) and from level III to IV (p less than 0.001). The incidence of saturation falling to less than 90% was 4.35%, 14.71% and 40% at sedation scores of II, III and IV respectively.

Adult↗

PubMed1989

Morbidity from subarachnoid spinal anaesthesia--a prospective study on the post-operative morbidity from subarachnoid spinal anaesthesia.

A clinical survey was conducted on 274 patients who had surgery under subarachnoid spinal anaesthesia. The anaesthetic was performed with either a 23 gauge or 25 gauge needle. All patients were interviewed on the second and sixth post-operative days. Data on morbidity (especially post-dural puncture headache and backache) was collated and analysed with respect to needle gauge. Backache was the most common complaint (20.5%). Using the finer needle did not reduce this aspect of morbidity. Post-dural puncture headache on the other hand was significantly reduced by the use of the finer 25 gauge needle (from 12.3% to 4.9%).

Adolescent↗