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Biomedical subjects

T Carter

Publications and source records attributed to T Carter.

67 records · Page 4Linked to original sources
PubMed1978

The relationship between sexual identification and the use of defense mechanisms.

A distinction is made between two levels of sexual identification. The deeper level was measured by May's Deprivation/Enhancement fantasy pattern, while the surface level was assessed using the Masculinity-Femininity of the Strong Vocational Interest Blank. These measures, while clearly differentiating between college males and females, were found to be unrelated to each other. Moreover, the deeper level was found to be related to the use of "masculine" and "feminine" defense mechanisms.

Journal Article↗
PubMed1976

Factors involved in the determination of triglycerides in serum: an international study.

Ten laboratories analysed five different specimens in duplicate on ten separate occasions by one, or several, of five common triglyceride methods. Simple statistical data are presented and, as far as possible, these are interpreted in the light of the methods used and the results of chemical analyses of the materials. Great variability was found between the results of the participating laboratories. The major factor involved seems to be the material specific nature of the methods under study. At least one method in common use is contraindicated.

Chromatography, Gas↗
PubMed1976

Evaluation of a new enzymatic kit for serum triglycerides.

We evaluated a new enzymatic kit for serum triglycerides (triacylglycerols) in two laboratories. The procedure involved both enzymatic hydrolysis of the triglycerides and conversion of the glycerol, which was linked to an indicator reaction. There was excellent agreement with the mechanized procedure of Kessler and Lederer and with a manual method. The test requires 50 mul of serum and can be completed in about 50 min. Inter- and intra-laboratory variation, linearity, accuracy, and specimen storage were studied.

Autoanalysis↗
PubMed1976

Results for serum cholesterol and triglycerides by gas-liquid chromatography, as compared with a continuous-flow technique.

We assessed the usefulness of gas-liquid chromatography forthe routine and reference measurement of cholesterol and triglycerides (triacylglycerols). Compared with results obtained by an AutoAnalyzer II method, correlation was good with both serum specimens (triglycerides, r = 0.88; cholesterol, r = 0.90) and lipoprotein fractions isolated by ultracentrifugation (triglycerides, r = 0.98; cholesterol, r = 0.98). However, none of the comparisons was completely free of analytical bias, and in general the AutoAnalyzer method underestimated the cholesterol value and overestimated triglycerides. The obvious advantage of the AutoAnalyzer is its greater analytical speed, but the chromatographic method appeared to be more accurate and precise and to suffer less from interfering substances, and in addition gave information about the cholesterol ester and triglyceride composition. We expect gas-liquid chromatography to be of major importance in the calibration of other analytical methods.

Autoanalysis↗
PubMed1971

New polarity suppressors in Escherichia coli: suppression and messenger RNA stability.

Two new polarity suppressors (Su27 and Su78) have been isolated in Escherichia coli. Both suppress polarity in the trp and lac operons, and neither shows codon specificity for suppression. Extreme polar mutants of the lac z gene that contain either Su27 or Su78 make mRNA from the entire operon; however, no active beta-galactosidase is translated from the z-gene messenger, and the amount of distal messenger is greater than would be expected from corresponding enzyme activities. Puromycin treatment of lac(+) strains mimics the effect of polar chain-termination mutations in destabilizing lac mRNA. This effect is completely reversed by Su27, and it is partially reversed by Su78. The results suggest that these suppressors act by stabilizing mRNA after premature termination of protein synthesis.

Acyltransferases↗
PubMedDate not supplied

Ground-based simulations of cosmic ray heavy ion interactions in spacecraft and planetary habitat shielding materials.

This paper surveys some recent accelerator-based measurements of the nuclear fragmentation of high energy nuclei in shielding and tissue-equivalent materials. These data are needed to make accurate predictions of the radiation field produced at depth in spacecraft and planetary habitat shielding materials and in the human body by heavy charged particles in the galactic cosmic radiation. Projectile-target combinations include 1 GeV/nucleon 56Fe incident on aluminum and graphite and 600 MeV/nucleon 56Fe and 290 MeV/nucleon 12C on polyethylene. We present examples of the dependence of fragmentation on material type and thickness, of a comparison between data and a fragmentation model, and of multiple fragments produced along the beam axis.

Cosmic Radiation↗
PubMedDate not supplied

Avitene granulomas of colonic serosa.

Avitene, microfibrillar collagen hemostat, is an absorbable topical hemostatic agent prepared from purified bovine corium collagen. A case is reported of a 58-year-old man who, one month after sigmoid colectomy for volvulus in which Avitene as used to control bleeding from a splenic capsular tear, developed symptoms of intestinal obstruction. On exploratory laparotomy, the transverse and descending colon had numerous 0.1 to 2.0 cm nodules, adherent to the serosa of the bowel and mesentery, with kinking and partial obstruction of the splenic flexure. Light microscopically, the nodules were found to be composed of chronic inflammatory and granulomatous reaction with numerous deposits of eosinophilic fibrillar material consistent with Avitene. Electron microscopic examination of the lesions and of Avitene confirmed the nature of this material. The practical and pathobiological implications of utilization of Avitene as a hemostatic agent are discussed.

Adipose Tissue↗
PubMedDate not supplied

Plasma digoxin levels in infants, children and adults, using a radioimmunoassay micromethod.

The radioimmunoassay method for estimation of plasma digoxin concentration was modified to use samples of 0.1 ml plasma for use in infants and children. The optimal daily maintenance dose for neonates, infants, and children was found to be between 0.01 and 0.015 mg/kg. Despite high plasma digoxin concentration (3-4 ng/ml) in some infants and children, no evidence of toxicity was found on electrocardiogram. 3 patients with accidental overdose, however, had plasma digoxin levels above 5 ng/ml and 2 of these had atrioventricular block.

Adolescent↗