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Biomedical subjects

T Chattopadhyay

Publications and source records attributed to T Chattopadhyay.

At least 19 recordsLinked to original sources
PubMed2004

Nomimmune hydrops fetalis due to Diamond-Blackfan anemia.

We describe case report of a baby with Diamond-Blackfan anemia, who presented as non-immune hydrops fetalis. The diagnosis was confirmed by measurement of red cell adenosine deaminase activity which is increased in Diamond-Blackfan anemia. At 2 years of age he is dependent on small dose of alternate day steroid to maintain his hemoglobin.

Anemia, Diamond-Blackfan↗
PubMed1997

Further biochemical and biophysical characterisation of scyllin, Scylla serrata hemolymph lectin.

The amino acid and carbohydrate analysis of scyllin, a low molecular weight lectin purified from Scylla serrata (edible crab) haemolymph reveal that scyllin is rich in acidic and neutral amino acids and contains high amount of mannose. UV absorption of scyllin is perturbed by DMSO at 272 nm showing the presence of tryptophan molecule in scyllin exposed and accessible to the solvent. The oxidation of tryptophan molecule by N-bromosuccinimide results in loss of haemagglutinating activity of lectin. The study of thermodynamic parameters of scyllin-glycoproteins interaction suggests that ceruloplasmin is the most potent inhibitors of scyllin of all the glycoproteins studied.

Amino Acids↗
PubMed1990

Therapeutic outcome of elderly and nonelderly patients receiving home intravenous antimicrobial therapy.

The therapeutic outcomes of elderly patients receiving home i.v. antimicrobial therapy were compared with those of younger patients receiving the same therapy. Using predetermined inclusion and exclusion criteria, 150 consecutively referred patients were accepted into the study. These patients were receiving home i.v. antimicrobial therapy from three home-health-care pharmacies (HHCPs). Referred patients were classified as elderly (greater than or equal to 62 years old) or nonelderly. Data for these patients were compiled retrospectively using interviews and chart reviews. Outcome of the i.v. antimicrobial therapy was rated as either adequate or inadequate based on predetermined criteria. Outcomes were analyzed for each HHCP and for the pooled data. The mean age of the pooled nonelderly group was 38 +/- 14 years, and the mean age of the pooled elderly group was 71 +/- 6 years. Adequate outcomes were noted in 70% of the pooled samples of elderly patients and 76% of the pooled samples of nonelderly patients. The difference between the outcomes of patients in the two age groups was not significant. In this carefully selected population, elderly and nonelderly patients receiving home i.v. antimicrobial therapy had similar therapeutic outcomes.

Adult↗