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Biomedical subjects

T Curković

Publications and source records attributed to T Curković.

5 recordsLinked to original sources

Interleukin 4, IgG and oligoclonal IgG in aqueous humor of cataract patients.

We measured interleukin 4, total IgG, IgG-albumin relative concentration ratio, and oligoclonal IgG in aqueous humors of patients with uncomplicated senile cataracts and cataracts complicated by previous uveitis of unknown etiology. The values of all mentioned parameters are significantly elevated in aqueous humors of patients with complicated cataracts. The possible implications of our findings are briefly discussed.

Aged↗

Measurement of intraocular IgA and IgM synthesis and filtration through the blood-aqueous barrier in cataract patients.

The authors have tested two formulas by means of which the filtrated and the intraocularly (intrathecally) synthesized fraction of particular protein can be distinguished. The laser nephelometric method was applied to determine the serum (IgG, IgA, IgM, C3, albumin), aqueous humor (IgA, IgM, albumin) and CSF (IgG, IgM, C3, albumin) protein values in 42 subjects to test two models in physiological conditions. It was confirmed that the best results were achieved using the formula after Stambuk. Computer simulation performed to compare the formulas after Stambuk and Reiber & Felgenhauer showed a strong correlation (r greater than 0.98) between the calculated filtrated fractions of both models in a wide range of different barrier permeabilities. Laser nephelometry proved to be a useful method to determine low IgA and IgM values in aqueous humor.

Adult↗

Combined technique of argon-laser and neodymium-YAG laser photocoagulation for narrow-or closed-angle glaucoma.

A combined laser technique was applied in 76 eyes with narrow- or closed-angle glaucoma. In the first act circular Argon-laser iridoplasty was performed, to be followed by peripheral Nd-YAG laser iridotomy. Before the laser application, intraocular pressure was decreased using medicamentous antiglaucoma therapy to 30 mmHg or less. Argon-laser iridoplasty was performed in the peripheral third of the total iris circumference applying cca 20 laser spots. Eight days later, Nd-YAG laser iridotomy was performed at the site of the previous Argon-laser spot. Postoperative intraocular pressure was normal in 64 out of 76 eyes (84.2%) on the last check-up, and the additional antiglaucoma medications was significantly reduced. In a small number of cases i.e. 24 eyes (31.6%), the medical therapy was altogether cancelled. In 12 eyes (15.8%) the laser treatment has failed, and antiglaucoma surgery had to be performed subsequently. The observation period ranged from 4 to 25 months.

Adult↗

[Retinoblastoma].

Basic elements of retinoblastoma were evaluated in a sample of 14 patients. The analysis of the sex distribution has revealed that a greater number of male children was affected by the disease (p = 0.64). The average age ranged from 2 months to 3.5 years. Usually the first visible symptom is a white pupillary reflex, while the first clinical findings show that there is a tumorous formation in the fundus. A significant correlation between the age of the patient and the length of his survival was found by Fisher's test, as well as between the laboratory findings of tumor cells in the optical nerve incision and the length of survival.

Child, Preschool↗

[Treatment of narrow- or closed-angle glaucoma using combined argon and Nd-YAG laser photocoagulation].

Combined laser technique was applied on 38 eyes with closed-angle glaucoma. In the first act circular argon laser iridoplasty was performed, followed by peripheral Nd-YAG iridotomy. First, intraocular pressure was decreased by anti-glaucoma medicament therapy to 30 mmHg or less. Then, circular argon laser iridoplasty was performed on the peripheral third of the total circumference of the iris (cca 20 spots). Eight days later, Nd-YAG laser iridotomy was performed at the location where previously a spot was made with argon laser. Postoperative intraocular pressure was normal in 84.2% at the last control examination and the anti-glaucoma medicament treatment was significantly reduced. In a smaller number of cases this treatment was cancelled all together. In 6 eyes (15.8%) laser treatment was not successful and anti-glaucoma surgery had to be performed subsequently. The observation period lasted from 3 to 15 months.

Adult↗