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Biomedical subjects

T D Kanareĭtseva

Publications and source records attributed to T D Kanareĭtseva.

17 recordsLinked to original sources
PubMed2003

[The stomach and duodenum condition in patients with chronic obstructive lung diseases].

Examining the gastroduodenal mucosa (GDM) in 61 patients with chronic obstructive pulmonary diseases (COPD) showed changes in the areas studied in all cases. GDM atrophy increased with the severity of COPD. Helicobacter pylori are essential in developing gastric pathology in patients with mild bronchopulmonary disease. The severity of atrophic gastritis increases with the longer duration of COPD and with more severity of hypoxia and bronchial obstruction.

Adolescent↗
PubMed1992

[Computer program for the analysis of clinical diagnostic errors based on a pathology database].

The program is tested on the material of 882 autopsy protocols. All parts of clinical and pathology diagnoses were included into the generation of the data base. Automatized analysis allowed to assess main characteristics of the patient material with a histogram demonstration of group statistics according to all positions considered as well as to obtain information on the influence of more complex pathology diagnosis of a main disease, sex and age on the frequency of clinical diagnosis mistakes.

Databases, Factual↗
PubMed1991

[Reflux gastritis in duodenal ulcer].

The results of a comprehensive examination of 44 patients with duodenal ulcer are analyzed. Reflux gastritis was detected in almost 50% of the patients. X-ray method, gastroduodenoscopy, and radiologic method for measuring the duodenal reflux in gastric contents portions were employed to diagnose duodenogastric reflux and reflux gastritis. The radiologic method was found the most informative. Reflux gastritis was finally diagnosed after histologic examination of gastric mucosa biopsy specimens. Increased count of IgE cells in these specimens may be considered as the marker of reflux gastritis. The authors come to a conclusion that reflux gastritis degree should be taken into consideration when choosing a method for conservative and radical treatment of duodenal ulcers.

Adolescent↗
PubMed1990

[The functional morphology of the gastric mucosa in duodenal ulcer and in the late period after isolated selective proximal vagotomy].

Pretrophic and moderately atrophic gastritis is found in the antrum in patients with noncomplicated duodenal ulcer. Normal mucosa or superficial gastritis were observed in the gastric body. Statistically significant worsening of the gastritis of both stomach areas without pronounced atrophic forms, stable decrease of the acid production and the number of parietal cells with a mild increase of the gastrin-producing cells of the antrum are found 1 to 8 years after the selective proximal vagotomy.

Adult↗
PubMed1989

[An analysis of the quality of the clinical diagnosis based on autopsy data].

The findings from 4359 autopsies made in 4 Moscow hospitals during 1986 were analyzed with two proposed tables. The primary materials were processes with a computer. Table 1 includes data on the total number of unrecognized cases by the main disease, major complications, concomitant and underlying diseases in terms of their category and cause of diagnosis discrepancy. The rate of the discrepancy between clinical and postmortem diagnoses averaged 21.6 +/- 4.7% by the main disease, that of unrecognized fatal complications and major concomitant and underlying diseases was found to be 7.6 and some 2%, respectively. By the categories, the analysis of diagnosis discrepancy indicated 35, 58.6, and 6.4% in Categories I, II, and III, respectively. Table 2 (combined correlational one) makes it possible to study the range of diagnostic errors in various diseases and to find typical mistakes made by clinicians. Analyzing the quality of clinical diagnosis according to the given pattern is of advantage in routine practice to obtain comparable consistent data, to make a thorough examination, and to generalized discrepancy cases of clinical and postmortem diagnoses.

Autopsy↗
PubMed1985

[Clinico-morphologic characteristics of reflux gastritis in patients with peptic ulcer before and after surgical intervention].

Experimental and clinical studies convincingly indicate that duodenal-gastric reflux may provoke the development of reflux gastritis with a characteristic clinico-morphological complex. However, the clinical picture of reflux gastritis in patients with stomach ulcer is not always typical, is frequently masked by the underlying disease and therefore is difficult for diagnosis. The necessity of the use of the laboratory and instrumental methods arises, with an obligatory histological examination. Morphological studies indicate the existence of certain characteristic signs of reflux gastritis, the detection of which makes this diagnosis valid.

Duodenal Ulcer↗
PubMed1980

[Functional state of the gastrin-producing cells in duodenal ulcer patients].

Electron microscopic and specific immunofluorescent studies revealed enhanced hormonal activity of the antral part of the stomach manifested in hyperplasia of gastrin-producing cells in patients with duodenal ulcer. A relationship between the level of stimulated gastric secretion, number of gastrin-producing cells and their functional activity was established. No correlation was found between the values of acidity and levels of basal and stimulated gastrin or the dependence of the latter parameters on the number and functional activity of gastrin-producing cells.

Adolescent↗
PubMed1975

[Comparative morphometric study of the fatty tissue of obese patients following diet therapy].

Results of morphometric studies of the subcutaneous fat tissue in patients with the metabolic-alimentary form of obesity of 3rd degree are discussed. A total of 27 biopsy specimens obtained from obese patients before and after the course of complex therapy with statistical treatment of the data on the electronic computer type M-222 were studied. A regular correlation between the volume of lipocytes and body weight was revealed: with an increase in excessive weight there were observed corresponding changes in the size of fat cells. In the process of treatment the obese patients showed a statistically reliable considerable decrease in the volume of fat cells, no marked changes in the total number there of as compared with initial parametres were noted.

Adipose Tissue↗
PubMed1975

[Study of some oxidoreductases in nerve tissue culture].

A change in the activity of succinic dehydrogenase, of the NAD- and NADP-diaphorases was studied in the dissociated culture of the cerebellum of neonatal rats under the effect of immune serum of the animals with an experimental allergic pertussis encephalomyelitis. There was revealed an increase in the activity of oligodendrocytes following a 3-hour exposure with the immune serum and a reduction of the activity of the enzymes under study in the same cells after a 12-hour exposure of the cultures with the serum. In difference from oligodendrocytes, the astrocytes displayed a high activity of all the enzymes under study after a 12-hour exposure.

Animals↗