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Biomedical subjects

T D Sabin

Publications and source records attributed to T D Sabin.

At least 19 recordsLinked to original sources
PubMed1986

Classification of peripheral neuropathy: the long and the short of it.

Insights into how the nervous system functions have often sprung from knowledge of the localization of nervous system diseases. Indeed, the recent rebirth of behavioral neurology has been sparked by new insights into the topography of higher cortical functions. Yet, the localization of disease affecting the peripheral nervous system is simply assumed to be a by-product of the beginning course in gross anatomy! Indeed, the anatomic sophistication laid out by Sunderland and reflected in the daily practice of electromyography might cause doubt as to the need for further inquiry into the problem of localization of disease within peripheral nervous system. There are, however, numerous problems in clinical practice that do not yield to the traditional root-plexus-nerve analysis of localization.

Animals↗
PubMed1985

Universal dissociated anesthesia due to bilateral brain-stem infarcts.

A 59-year-old man had loss of pin-prick and temperature sensation over his head, face, neck, trunk, and all extremities while light touch, vibration, joint position sense, and deep pain were preserved. This was the cumulative result of infarctions in the territories of the right superior cerebellar and left posterior inferior cerebellar arteries that occurred three years apart. To our knowledge, a syndrome of bilateral discrete interruption of spinothalamic tracts and of the spinal tracts of the trigeminal system in the brain stem has not been reported. Dissociated sensory loss enveloping the entire body accompanied by truncal and limb ataxia without weakness demonstrated a striking clinical picture. The preservation of deep somatic and visceral pain when cutaneous pain sensation was lost was another notable feature. We review the causes of widespread dissociated sensory loss and discuss the implications of the dissociation of deep from superficial pain.

Brain Stem↗
PubMed1982

Lithium in aggressive behavior.

A patient with intractable aggression was treated with lithium carbonate. On the basis of the authors' study and their review of the literature, they conclude that lithium may exacerbate the interictal aggression sometimes noted in patients with temporal lobe spike activity.

Adult↗
PubMed1981

Diabetic truncal polyneuropathy.

Diabetic truncal polyneuropathy is a clinical entity characterized by sensory deficit in the distribution of the thoracic intercostal nerves. The sensory loss is relatively symmetric and involves multiple thoracic dermatomes, beginning close to the anterior midline. Diabetic truncal polyneuropathy occurs in patients with advanced distal polyneuropathy involving the limbs. This entity is important because it can be confused with myelopathies that produce sensory levels over the torso. Moreover, recognition of diabetic truncal polyneuropathy is important since this disorder is associated with autonomic neuropathy.

Adult↗
PubMed1981

Tonic fecal seizures in nonketotic hyperglycemia of diabetes mellitus.

Three patients had recurrent focal motor seizures as the first manifestation of nonketotic hyperglycemia (NKHG) of diabetes mellitus. The seizures were characterized by stereotypical tonic changes in body posture and arrest of speech that have been associated with supplementary motor area seizures. Recognition of the link between this unusual form of focal epilepsy and NKHG would help in the early diagnosis and treatment of the serious underlying metabolic disturbance.

Aged↗
PubMed1978

Anterior cervical arachnoid cyst simulating syringomyelia: a case with preceding posterior arachnoid cysts.

An arachnoid cyst lying anterior to the cervical cord at level C6-7 was found in a 28-year-old woman believed to have syringomyelia. This diagnosis was based both on previous findings at laminectomy and on computerized tomography. The diagnosis of arachnoid cyst was suspected because of clinical features atypical for classical syringomyelia and a history of arachnoid cysts found during childhood. Air myelography demonstrated an extramedullary intradural mass anteriorly that proved to be an arachnoid cyst. Drainage and subtotal resection resulted in marked clinical improvement. This case illustrates the need for reevaluation when a patient with "known" syringomyelia presents an atypical clinical picture. Anterior cervical arachnoid cyst, which may accompany or succeed posterior arachnoid cysts, should be considered.

Adolescent↗