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Biomedical subjects

T D Spera

Publications and source records attributed to T D Spera.

5 recordsLinked to original sources

Local fibrinolysis in cerebral venous thrombosis.

Extensive cerebral venous sinus thrombosis may cause death or severe neurologic sequelae. A minimally responsive 10-year-old boy with thrombosis of the superior sagittal sinus, left transverse and left sigmoid sinus, torcular, vein of Galen, and straight sinus underwent fibrinolytic therapy with urokinase during transfemoral venous angiography. He improved dramatically during the procedure as antegrade venous flow was re-established. Local thrombolytic therapy may be beneficial for other patients with rapid neurologic deterioration caused by extensive thrombosis of superficial and deep venous structures.

Cerebral Angiography↗

A physician questionnaire study of the net cost of computerized tomographic scanning.

This paper reports the results of a physician questionnaire study of the net cost impact of CT Scanning on the health care system. The study objective is accomplished by questioning physicians, on a case-by-case basis, on the number and type of diagnostic tests and hospital care which would have been provided in lieu of CT. These findings indicate that CT Scanning, while expensive on a per use basis, results in significant cost savings on a per case basis because it eliminates the need for multiple alternative tests and hospital stays. Finally, the controversy over the cost of CT Scanning is attributed not to the intrinsic merits of CT but rather to structural elements within the health care system which create disincentives to economize.

Brain Diseases↗

Cerebral distribution of contrast medium during slow intracarotid infusion.

A prospective study was performed to evaluate in vivo the uniformity of cerebral distribution of iodinated contrast medium during slow intraarterial injection at rates used for chemotherapy installation in the internal carotid artery. We evaluated seven patients with primary intracranial neoplasms with routine film-screen angiography and with digital angiography during slow infusion. In six internal carotid artery injections the distribution of contrast material was identical during the late arterial phase of routine angiography and the digital study. In three vertebral artery injections the opacification during the slow infusion was inadequate to make meaningful comparison. Our results indicate that solutions infused into the internal carotid artery at rates as low as 0.25 ml/sec are distributed well throughout the carotid territory opacified during the late arterial phase of film-screen angiography.

Angiography↗