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Biomedical subjects

T D Weaver

Publications and source records attributed to T D Weaver.

7 recordsLinked to original sources

Multiple onychocryptosis following treatment of onychomycosis with oral terbinafine.

The authors report an unusual case of multiple onychocryptosis, which developed following treatment of onychomycosis with oral terbinafine. With new growth of the healthy nail plate, the distal aspect of multiple toenails became ingrown with periungual inflammation. This required several minor surgical procedures to alleviate the onychocryptosis. The authors present this case report as a potential complication of oral antifungal therapy.

Administration, Oral↗

Phenol and alcohol chemical matrixectomy in diabetic versus nondiabetic patients. A retrospective study.

The authors performed a retrospective study of the safety and efficacy of toenail phenol and alcohol chemical matrixectomy in diabetic versus nondiabetic patients. Participating in the study were 66 patients, who underwent 137 nail procedures. The diabetic group consisted of 18 patients who underwent 39 procedures; the nondiabetic group consisted of 48 patients who underwent 98 procedures. The mean (+/- SD) healing time was 44 +/- 25 days for the diabetic group and 43 +/- 24 days for the nondiabetic group. The infection rate was 10.3% (4 of 39 procedures) for the diabetic group and 12.2% (12 of 98 procedures) for the nondiabetic group. In addition to validating this procedure for diabetic patients, this study showed no significant differences in the rate of postoperative complications between the two groups.

2-Propanol↗

Charcot's joint following Keller arthroplasty. A case report.

Neuropathic osteoarthropathy, i.e., Charcot's joint, has not previously been reported as a sequela of elective foot surgery. The authors present a challenging case of a patient with long-standing diabetes mellitus and peripheral neuropathy who developed neuropathic osteoarthropathy after a Keller arthroplasty for a recalcitrant hallux ulcer. The radiographic findings, diagnostic tests, and histopathology are discussed. Finally, the authors offer suggestions for surgeons contemplating a Keller arthroplasty for patients with peripheral neuropathy.

Arthropathy, Neurogenic↗

MacMolecular: a program for visualization of molecular structures on the Macintosh.

MacMolecular displays small- to medium-sized biomolecules, with particular emphasis on peptides. It has been developed to run on color Macintosh computers. The display can be stick, ball and stick, depth cued by thickness stick, or several types of space-filling representations. The program takes input from standard PDB files, simple Cartesian coordinate files, and, in addition, from Kinemage files in which atom information has been included. The program allows color changes of various types as well as the normal functions of translation, rotation, and zooming. In addition, animation files may be produced for subsequent display. Bonding of atoms is done by a distance algorithm (standard) or sequentially to properly display C alpha traces and traces of peptides containing simplified representations of amino acids. Stereo viewing is available, and manipulated structures which were drawn from PDB files can be written out to new PDB files. In addition, PICT files of the drawing window can be generated.

Alanine↗

Subungual glomus tumor of the hallux.

An unusual case of subungual glomus tumor involving the left hallux of a forty-year-old black man is presented, with a review of the literature. The histopathologic appearance, clinical presentation, differential diagnosis, and treatment for a subungual glomus tumor are reviewed. The glomus tumor is a rare hamartomatous overgrowth of the normal glomus elements found in the skin. The tumor presents as a painful, benign growth, most often in the digits.

Adult↗

Ganglion cyst of the hallux: an aberrant presentation.

Ganglion cysts are benign, thin walled, fluid-filled lesions commonly occurring in the distal extremities. Although widely debated in the literature, a true, identifiable etiology has remained elusive. The authors report on a ganglion cyst with a unique presentation on the hallux, and a review of the literature.

Adult↗