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Biomedical subjects

T David

Publications and source records attributed to T David.

At least 55 records · Page 3Linked to original sources
PubMed1985

[Lumbar arthrodesis: results after more than 10 years].

Two hundred and seventy four patients had a lumbar spine fusion between 1949/1971. Seventy-five of them were available for review more than 10 years after the procedure. There were twenty spondylolisthesis, forty-eight degenerative discopathies, six cases of Pott's disease and one benign tumour. All the patients had been treated conservatively before the surgical procedure for an average of 7 years and were still complaining of chronic low back pain. All the cases reviewed had fused. The functional results were not related to the surgical technique, which varied during this period: eight posterior mid-line grafts, seventeen interbody fusions and fifty combined anterior and posterior approaches sometimes used because of a primary failure of fusion and no postero-lateral fusions. The average follow-up was 13 years with a range from 10 to 26 years. The clinical results were satisfactory in 74 p. 100 of the cases. There were thirteen failures. Seven of these patients had been operated on before the era of systematic preoperative discography and psychological evaluation and the failure was primary. Other failures were observed at about the tenth post-operative year. The results were better in spondylolisthesis with isthmic lesions, rather than in degenerative spondylolisthesis. They were better in pure low back pain than when the pain associated with sciatica. They were better when fusion was limited to one or two levels. Radiographs ten years after the procedure frequently showed evidence of degenerative lesions of the disc above the level of the fusion and, at the same time, some slipping of the upper vertebra. Fortunately, there was no correlation between the radiological appearances and the clinical results.

Adolescent↗
PubMed1985

[Femoral lengthening by transverse diaphyseal osteotomy. Experimental study in the dog].

Previous work has shown that extensive areas of bone necrosis developed after Z-osteotomies of the femoral shaft. A study was made on 11 dogs to compare the effects of a transverse osteotomy followed by immediate lengthening, stabilisation by plates and bone grafting. The bone vitality was studied at 8 and 16 weeks by histological sections and angiography. Attention was focussed on the area of lengthening and the bone ends. The results showed the superiority of transverse osteotomy over Z-osteotomy. Bone necrosis diminished at the 16 th week. In the area of lengthening, the vascularity of the grafts was satisfactory. In contrast, the tendons of the Z-osteotomy showed constant necrosis.

Animals↗
PubMed1979

Aorta-coronary bypass in a patient with sickle cell trait.

A triple aorto-coronary bypass was performed in a patient with sickle cell trait. Partial exchange transfusion with normal packed erythrocytes was used in preparation of the patient for extracorporeal circulation, hypothermia and cardioplegic arrest.

Anemia, Sickle Cell↗
PubMedDate not supplied

[The school for patients with chronic backache. Retrospective study of 93 severely handicapped patients with backache and their socio-occupational status].

A small percentage of low back pain sufferers are resistant to the various types of treatment tried and the problem becomes chronic. It is for this severely incapacitated group, threatened by socio-occupational misfortune, that we created: the School for Chronic Low Back Pain Sufferers. One hundred and five patients in whom treatment had failed were included after insurance programmes had agreed to provide cover. The system is of a multidisciplinary nature with hospitalisation for 5 days. The fate of 93 of these patients is known with a mean follow-up of 1 year. Quantified initial evaluation on an obstacle course confirmed that even severe low back pain sufferers were unaware of the basic rules for protection of the spine (mean score of 14/50 on admission). Socio-occupational fate analysed on the basis of a questionnaire showed: a high satisfaction index (90%) regardless of the subsequent outcome, and a correlation between follow-up time after the programme and the decrease in painful attacks (p less than 0.03, r = 0.23) or consumption of medications (p less than 0.01, r = 0.29). The relative simplicity of the system proposed, the situation of therapeutic impasse in which the patients for whom it is intended find themselves, the short time required and the results obtained confirm the importance of this multidisciplinary management approach being able to best envisage the possibilities of rehabilitation of the chronic low back pain sufferer, in particular when there are repeated periods off work.

Adult↗
PubMedDate not supplied

Lamellar keratoplasty with the Barraquer microkeratome.

Lamellar keratoplasty was performed in 17 eyes: 6 with corneal opacities following epidemic keratoconjunctivitis, 3 with herpes keratitis, 2 with anterior corneal dystrophies, and 6 others. The Barraquer microkeratome was used for the resection in both the host and the donor. A technique is described to correct major disparities in diameter between the bed and the donor disc. In eyes with vision limited only by corneal diseases (11), the best postoperative spectacle corrected visual acuity was 20/25; the mean postoperative spectacle corrected visual acuity for the 11 eyes was 20/40.

Adolescent↗
PubMedDate not supplied

[Hyponatremia and convulsions in the postoperative period in children].

Four children undergoing surgery presented with seizures and hyponatremia 12 hours after anesthesia. One child died with cerebral oedema, the others recovered. The respective roles of hypo-osmolar perfusions and ADH secretion are discussed. Ionogram before surgery, supervision of weight and diuresis and correct fluid management should prevent these postoperative complications.

Child, Preschool↗
PubMedDate not supplied

The constant itch.

Explore the source record for details and available documents.

Child, Preschool↗
PubMedDate not supplied

[A case of 49 XXXXY gonadosomatic dysgenesis: clinical elements and biological consequences of polysomy X].

Discovery of 49 XXXXY syndrome in a six years young boy allows description of the main clinical characteristics of this disease: hypotrophy, facial anomalies, hypogenitalism, delayed speech development and oligophrenia. Radio-cubital synostosis is quite specific in this syndrome. The hypothesis of a correlation between clinical anomalies and excess of genes induced by polysomia has been suggested. We give results of five X-linked enzymatic activities: steroid sulfatase (STS) (located on the probably noninactivated segment), Hypoxanthine Guanine Phosphoribosyl Transferase (HGPRT), Glucose 6 Phosphate Déshydrogenase (G6PD), Phospho Glycerate Kinase (PGK), Alpha Galactosidase A (Alpha GAL A). Only STS activity seems to be significatively increased.

Child↗
PubMedDate not supplied

Urinary uric acid excretion in patients with carcinoma of the cervix undergoing intracavitary radium therapy.

An attempt is made here to determine the pattern of urinary uric acid excretion in patients with carcinoma of the cervix undergoing intracavitary radium therapy. Eight patients from the Philippine General Hospital were studied using 24-hour urine collection method to study the uric acid level. Result showed a proportionate increased in uric acid excretion with increasing dose of radiation up to 4,800-5,400 rads, after which, uric acid excretion produced an unexpected downtrend even with continued radiation. Maximum uric acid excretion ranged from 680-1,500 mg% with a mean of 1,005 +/- 100 mg%.

Adult↗