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Biomedical subjects

T Devine

Publications and source records attributed to T Devine.

13 recordsLinked to original sources
PubMed1997

Abdominal aortic aneurysms. The old and the new.

Abdominal aortic aneurysms are more frequently diagnosed while they are asymptomatic, by ultrasound scanning or computerized tomography (CT). Large aneurysms should be treated. Open surgical repair is well proven but is a major procedure with some risk and a slow convalescence. New endoluminal techniques, inserting grafts through the femoral artery involve minimal trauma and risk, with rapid recovery, but long term success has yet to be confirmed. At present, we consider that endoluminal grafts should be reserved for patients at high risk, but with increasing experience they could be used in more than 50% of cases.

Angiography↗
PubMed1993

Surfactant therapy failure identifies infants at risk for pulmonary mortality.

OBJECTIVE: To characterize the clinical features of infants who do not respond to surfactant therapy. DESIGN: Patient series, chart review. SETTING: Academic referral neonatal intensive care unit. PATIENTS/SELECTION: Ninety-nine consecutive infants with respiratory distress syndrome who received surfactant therapy and 107 infants from the 2 years prior to initiation of surfactant therapy matched for birth weight, race, sex, gestational age, chronological age, and disease severity. MEASUREMENTS/RESULTS: Oxygen index was used to quantitate response to surfactant therapy. A 25% decrease in oxygen index 6 hours after the first surfactant dose was significantly different from that of the matched historical cohort (P = .04). Oxygen index decreased 25% or more in 49 infants, the response group, while oxygen index decreased less than 25% or increased following therapy in the remaining 50 infants, the nonresponse group. Pulmonary interstitial emphysema occurred more frequently in the nonresponse group. The only deaths from pulmonary causes at 10 days of age or younger occurred in the nonresponse group (n = 11). CONCLUSIONS: Pulmonary processes unresponsive to surfactant therapy contribute to morbidity and mortality in newborn respiratory distress syndrome. Classifying respiratory distress syndrome as "surfactant responsive" or "surfactant unresponsive" offers a scheme by which to investigate alternative explanations and interventions for newborn respiratory distress syndrome.

Female↗
PubMed1988

Leg ulcers.

Explore the source record for details and available documents.

Adult↗
PubMed1986

L7-S1 fixation-fusion for treatment of cauda equina compression in the dog.

The L7-S1 fixation-fusion technique for treatment of cauda equina compression was performed on 14 dogs, 13 of which were 6 years old or older, were severely lame, and had ventral bridging spondylitis at the L7-S1 vertebrae. One dog, 3 months old, had a congenital malformation of the L7 vertebra. The principles of the L7-S1 fusion technique were to expand the L7-S1 intervertebral foramina and spinal canal, remove pressure on the nerve roots, and provide stability to the L7-S1 vertebrae. This technique appeared to be applicable clinically for restoring normal function and activity to dogs with cauda equina compression.

Animals↗
PubMed1985

Trochlear recession for correction of luxating patella in the dog.

Trochlear recession is a surgical technique for stabilizing luxating patellas by recessing the trochlear sulcus 1 to 2 mm. The smooth hyaline cartilage of the articulating trochlear surface is preserved. This technique has provided excellent results in 41 stifles of 28 dogs, as determined by a 6-month to 6-year follow-up, with an average follow-up period of 3.2 years.

Animals↗
PubMed1984

Stereoselective binding of disopyramide to human plasma protein.

The binding of racemic disopyramide and its two enantiomers to protein were compared in two samples of human plasma, two samples of freshly drawn serum and in a solution of alpha 1-acid glycoprotein. The binding of S(+)-disopyramide was higher at all concentrations as compared to to R(-)-disopyramide, and the binding of the racemate was intermediate. Differences in binding were due to differences in the association constant.

Binding Sites↗
PubMed1984

Cranial tibial wedge osteotomy: a technique for eliminating cranial tibial thrust in cranial cruciate ligament repair.

Cranial tibial wedge osteotomy, surgical technique for cranial cruciate ligament rupture, was performed on 19 stifles in dogs. This procedure leveled the tibial plateau, thus causing weight-bearing forces to be compressive and eliminating cranial tibial thrust. Without cranial tibial thrust, which was antagonistic to the cranial cruciate ligament and its surgical reconstruction, cruciate ligament repairs were allowed to heal without constant loads. This technique was meant to be used as an adjunct to other cranial cruciate ligament repair techniques.

Animals↗
PubMed1983

Cranial tibial thrust: a primary force in the canine stifle.

A cranially directed force identified within the canine stifle joint was termed cranial tibial thrust. It was generated during weight bearing by tibial compression, of which the tarsal tendon of the biceps femoris is a major contributor, and by the slope of the tibial plateau, found to have a mean cranially directed inclination of 22.6 degrees. This force may be an important factor in cranial cruciate ligament rupture and in generation of cranial drawer sign.

Animals↗
PubMed1982

Wedge recession for treatment of recurrent luxation of the patella: a preliminary report.

Wedge recession is a method which utilizes the geometry of similar triangles to recess an articular wedge into the underlying bone. This concept has been applied to congenital luxating patellae in the dog. A trochlear wedge recession deepens the femoral trochlea and provides stability to the patella. Preliminary trials of the procedure in dogs produced excellent results.

Animals↗