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Biomedical subjects

T Di Prima

Publications and source records attributed to T Di Prima.

5 recordsLinked to original sources
PubMed1990

[A critical review of the results of clinical experimentation with topical minoxidil 2%].

The results of clinical double-blind trials using minoxidil 2% demonstrate the real efficacy of the drug in producing satisfactory esthetical results in some 30% of treated patients. One aspect of the results of this research which is not yet clear is the significant increase in the number of hairs, also found in voluntary subjects treated with placebo. In the present study is hypothesised that this increase may be partially explained by the failure to take into account the physiological seasonal variations in hair density, and by the confusion caused by the use of the "non-vello" category which is used to describe terminal (thick) and indeterminate (thin) hairs. In our study placebo failed to produce a significant increase in the number of terminal hairs, thus explaining why, even in the presence of an increased number of "non-vello" hairs, on average there was no real cosmetic benefit in these subjects.

Administration, Topical↗
PubMed1989

[Use of an MAO inhibitor in the treatment of psoriasis vulgaris].

Thirteen patients suffering from psoriasis vulgaris of middle-high severity, were treated with tranylcypromine (5 mg once a day) or with placebo during a four months period, following a double-blind randomized trial. Results were evaluated with a statistical analysis of the data obtained with a PASI method. Tranylcypromine, an MAOI drug, appears to be effective in reducing the extension and severity of lesions.

Adolescent↗
PubMed1986

Ciclopiroxolamine: clinical and microbiological considerations. Preliminary data.

Ciclopiroxolamine's action has been evaluated in 20 cases of dermatophytosis. The minimum inhibitory concentrations (MIC) for the strains was determined in vitro before treatment (To), after the 4th day (T4), and after the 7th day (T7) of treatment, in relation with the drug's fungicide effect. No significant variation was observed among the MIC values. By comparing the MIC of T4 versus the MIC of To a 0.93 coefficient of linear correlation was obtained while in comparing T7 versus T4 the coefficient was equivalent to 1.0. After 7 days of treatment 5 patients clinically recovered, 11 improved and 4 showed no improvement. Drug tolerance was excellent except for one case.

Arthrodermataceae↗