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Biomedical subjects

T Domzał

Publications and source records attributed to T Domzał.

At least 37 records · Page 2Linked to original sources
PubMedDate not supplied

[Usefulness of 24-hour EEG recording in the diagnosis of epilepsy].

The authors observed 45 patients with epileptic seizures, with suspected epilepsy and with other types of seizures recoding the bioelectric activity of the brain during 24 hours on a magnetic tape with a Medilog 9000 Oxford apparatus. Continuous recording, as compared with routine short-lasting recording, increased the detectability of changes in epilepsy from 50% to 83% of cases, that is by over 30%. The method is very useful in the diagnosis of epilepsy and should be applied in particularly difficult cases.

Adolescent↗
PubMedDate not supplied

[Cavinton in the treatment of ischemic cerebral stroke. Clinical and computerized-tomographic evaluation].

Intravenous Cavinton (ethyl ester of apovincaminic acid) was given to 27 patients with acute ischaemic stroke, while 30 patients were given aminophylline twice daily during 10 days. The results of this treatment was compared on the basis of clinical manifestations and changes in computerized tomograms (CT) before and after the treatment. It was found that Cavinton gave similar results as aminophylline and other vasoactive preparations studied by other authors. In the group of severe strokes better results were observed after Cavinton, --out of 14 patients 2 died and 12 improved. In the aminophylline group 5 out of 10 patients died, and in 2 no improvement was observed. Clinical improvement was not correlated with CT improvement, while a significant correlation was observed between the state of the patient during admission and the size of the focus in CT. Cavinton had a significantly greater effect on the regression of CT changes.

Adult↗
PubMedDate not supplied

[Dynamics of clinical changes in correlation with computerized tomography in ischemic strokes].

Sixty patients with ischaemic stroke were studied observing during the acute period of the disease (10 days) changes in their neurological state in relation to findings in computerized tomography. It was found that in 24 patients with serious state changes prevailed involving nearly the whole lobe in CT. In patients with minor stroke CT demonstrated major lesions with involvement of a whole lobe as well as small deep lesions and cortical foci. In 27 patients the first CT examination demonstrated extensive lesions involving a whole lobe or a hemisphere. In this group clinical manifestations regressed completely in 3 cases within 10 days, in 15 cases an improvement was observed, 3 cases failed to improve and 6 patients died. In 12 cases with small cortical lesions regression of clinical manifestations was observed in 3 patients, 8 patients improved and one failed to improve. These observations showed a certain correlation between the clinical state and CT findings. Prognostic conclusions could be reached, however, only if a correlation existed between the clinical picture and CT. In case of lack of agreement, that is if extensive lesions coexisted with slight clinical changes or small lesions with a serious condition the clinical picture was of greater prognostic significance than CT findings.

Acute Disease↗
PubMedDate not supplied

[Faciolingual dyskinesia].

The authors report 4 cases of faciolingual dyskinesias associated with involuntary movements of extremities and akinetic seizures in 12 cases. Improvement followed treatment with Rivotril. The syndrome is undoubtedly of organic extrapyramidal character, the disturbances probably orginating in reticular formation of the brainstem.

Aged↗
PubMedDate not supplied

[Electromyographic study of mentalis muscle reaction to pain].

Three types of muscular reaction to pain were distinguished. Type I--a defensive reaction to a noxious stimulus, type II--muscular guarding at the site of pain, type III--suffering expression. The third type includes reaction of facial muscles discernible only at high pain intensity in subjects with hypersensitivity to pain. In a search for this reaction in all pains electromyographic investigations of the mentalis muscle were carried out since their connection with nociceptive stimulation is made use of in the sign of Marinesco-Radovici. In 18 out of 20 patients with sciatic pain spontaneous activity was observed in the mentalis muscle. Intensification of pain caused by nerve stretching (straight-leg-raising test) evoked activity of these muscles in all studied patients and its intensity was higher. The observed reaction may be an objective evidence of suffering.

Adult↗
PubMedDate not supplied

[Diurnal rhythm of pain in sciatica. Preliminary report].

Similarly as nearly all processes taking place continuously in the organism pain shows also frequently a circadian rhythm. In 30 patients with ischalgia pain intensity was studied over 24-hour periods during 7 successive days. The patients noted graphically the intensity of pain on a specially prepared scale. In the light of the data obtained from the patients three types of circadian pain rhythm curves were isolated. In 83,3% of cases the co urse of pain had an evident circadian rhythm returning during successive days. In 19 cases (63.3%) pain was particularly increased in the evening and night hours. In 6 cases (20%) the peak intensity of pain was in the morning hours (5-10 a.m.). In the remaining 5 cases (16%) its intensity was unchanged, without any circadian fluctuations. No relationship was demonstrated between pain rhythm and the age, sex, disease duration, spinal radiological changes, sensory or motor deficit. Pain rhythm is individual feature connected, probably, with other rhythmic processes in the organism, particularly with the rhythm of corticosteroid or endorphin release. Increased intensity of pain may be connected with falling level of these substances in the organism. In 35 patients with a significant nocturnal rhythm of ischalgic pain a trial was undertaken of treating the pain with dexomethasone administered in the evening hours in the painless period. The doses were 1-2 mg. In nearly 70% of cases (24 patients) a good effect of this treatment was obtained. This work based exclusively on clinical observations requires further studies and it is regarded by the authors as a preliminary communication.

Adult↗
PubMedDate not supplied

[Ceruloplasmin and copper in the serum of patients with amyotrophic lateral sclerosis (ALS)].

The serum level of ceruloplasmin and copper were determined in 14 patients with ALS, 9 with Wilson's disease and 10 with other brain diseases. The enzyme level in 8 patients with ALS (57%) was decreased, similarly as in 8 with Wilson's disease (89%), and 2 (20%) in the control group. The mean ceruloplasmin level in the group of patients with Wilson's disease was 50% that in ALS patients. The copper level was decreased in only 1 ALS patient and 1 in the control group, while in patients with Wilson's disease it was low in 8 cases. These changes may be an effect as well as a cause of motor neuron disease.

Amyotrophic Lateral Sclerosis↗
PubMedDate not supplied

[Type of pain, personality traits and effectiveness of modified acupuncture].

In 50 patients with headaches and 50 with radicular pains pain sensitivity and pain tolerance as well as personality traits (Eysenck and Cattell questionnaire) were determined and a modification of acupuncture (with additional chemical stimulation) was used for treatment. The results of treatment were compared with personality traits. Differences were found in the personality traits between patients with paroxysmal headaches and patients with radicular pains. No statistically significant correlation was found, on the other hand, between the results of treatment and personality traits. The obtained results were best in the group of patients with paroxysmal headaches (permanent analgesic effect obtained in 70% of cases). The results of treatment obtained in the group of patients with continuous headaches and with radicular pains were similar. In patients with a lower threshold of pain sensitivity a higher proportion of permanent disappearance of pain was observed after treatment, and this observation may be useful for establishing indications to this therapy. Lack of any influence of personality traits on the result of this modified acupuncture may suggest that the basic analgesic action of these procedure is at lower levels of the nervous system and that it causes blockade of inflow of pain stimuli.

Acupuncture Therapy↗
PubMedDate not supplied

[Evoked cortical somatosensory potentials in painful cervicobrachial radicular syndromes].

The authors determined the subjective, objective and maximal pain threshold by means of electrical stimulation in two groups of subjects. Group I comprised healthy subjects, group II patients with right-sided radicular cervicobrachial pains. The method applied by the authors for objective determination of pain threshold with evoked cortical somatosensory potential differentiated both groups which suggests its practical usefulness in clinical practice and expertise.

Brachial Plexus Neuritis↗
PubMedDate not supplied

[Cervical discopathy, cervical migraine and vertebrobasilar arterial insufficiency: Clinical correlations].

The pathogenesis of cervical migraine may suggest that a connection exists between it and cervical discopathy and also vertebrobasilar arterial insufficiency. This correlation was studied in a group of 103 patients subjected to clinical observations. In 83 of them cervical discopathy was found, in 69 cervical migraine and in 40 vertebrobasilar insufficiency were present. Among those with discopathy migraine was present in 63.6% of cases, and vertebrobasilar insufficiency in 31%. In patients with cervical migraine degenerative changes of the type of cervical discopathy were present in 90% of cases, although in only 56.5% of cases clinical signs were present connected with these changes. Vertebrobasilar insufficiency was present in 45% of patients with cervical migraine, that is more frequently than in discopathy. In the group with vertebrobasilar insufficiency radiological changes in the cervical spine were present in 77.5% of cases and the same proportion of patients in this group had cervical migraine. These numbers confirm the connection between cervical migraine and radiological changes and clinical manifestations of discopathy, and they indicate also that cervical migraine may be a successive stage of vascular changes leading to circulatory failure in the area supplied by vertebral arteries. This failure may have a different course and pathological mechanism. In 12.5% of patients in this group no cervical migraine or radiological changes were demonstrated. The term "cervical migraine" seems inappropriate since this type of headache has another substrate and mechanism than true migraine.

Adult↗
PubMedDate not supplied

[Acupuncture in headache and radicular syndromes].

The reported own experiences are related to acupuncture with injections of 10% NaCl solution (irritating the nerve endings) into selected points. Since 1973 this method was applied in 171 patients with radicular painful syndromes and 120 patients with headaches. In a group of 107 cases of sciatic pain a persistent analgesic effect was achieved in 30 cases (28%) and immediate disappearance of pain occurred in 21 cases (20%). In a group of 64 patients with shoulder pains a persistent effect was obtained in 36 cases (56%) and immediate but transient in 7 (10,9%). Among 43 patients with migraine a persistent good effect was observed in 24 cases (55,8%) and an immediate relief which was transient in 9 cases (20,9%). In 77 cases of vasomotor headaches a persistent effect was noticed in 37 patients (48%) and an immediate transient one in 23 (29,8%). It is not absolutely necessary to insert the needles into the traditional points accepted in classic acupuncture. During one procedure from 3 to 10 needles were inserted leaving them for about 15 minutes. From 3 to 15 procedures were given, mostly on consecutive days until a significant effect was obtained.

Acupuncture Therapy↗
PubMedDate not supplied

[Cerebrolysin in treatment of acute ischemic stroke].

Cerebrolysin is composed of low molecular peptides and free amino-acids and as a nootropic drug it administered in various diseases of central nervous system. In an open clinical trial patients with acute ischaemic stroke in the region of the middle cerebral artery, were treated. Cerebrolysin was administered as intravenous infusion in daily dose of 15 ml during 21 days. Recovery in 10 patients and improvement in 3 was obtained and only one patient died. The results were compared to the large group of 108 patients treated earlier with other drugs. Therapeutic effect was similar in all groups.

Aged↗
PubMedDate not supplied

[Vertigo: its clinical and electrophysiological correlations].

In 41 cases of vertigo without abnormalities in neurological examinations BAEP examination, specialistic otological examination, X-ray of the cervical spine were done. In most cases Doppler USG examination of the carotid and vertebral arteries and EEG and CT of the head were obtained. The most frequent abnormality in these examinations were changes in cervical spine found in 30 cases (90%) and in BAEP--36.5%. BAEP changes were most frequently found in patients with known factors for dizziness--41.2%, followed by those with CT changes--33.3%, cervical spine changes--28.6% and changes in USG of the arteries supplying the brain from the neck.

Adult↗
PubMedDate not supplied

[Electrophysiological pattern of sleep after stroke].

The aim of the study was electrophysiological recording of sleep in patients after damage to the right or left cerebral hemisphere after stroke. The studied material comprised 15 patients ages 45 to 75 years, ten of whom had ischaemic stroke in the area of vascularization of the middle cerebral artery as confirmed by CT. In 5 cases the left and in 5 the right hemisphere was damaged. Five patients without organic brain changes served as controls. Sleep study was carried out 4 weeks after stroke, the patients were EEG-monitored during 9 hours of sleep. In stroke patients disruption of the normal pattern of EEG during sleep was found, with absence of sleep cycles and disturbed sequence of these stages. Changes were noted also in the durations of stages N-REM, REM, WASO. In left hemisphere damage the duration of N-REM was shorter, and that of REM was longer than in cases with right hemisphere damage and in controls. After stroke the per cent proportion of the first stage of sleep N-REM was higher mainly in right-sided lesions, while the per cent proportions of stages II and III + IV were lower than in controls. The latency of sleep onset and onset of the first REM was evidently shorter after stroke.

Aged↗
PubMedDate not supplied

[Status epilepticus: clinical features, causes and management].

Status epilepticus with generalized seizures may sometimes develop in epileptic patient who does not recover between attacks. Such a state is life-threatening and requires immediate intervention. Own experience with 22 patients suffering from status epilepticus out of 100 epileptic patients treated at the hospital. Management of status epilepticus is also discussed. Diazepam should be given intravenously or clonazepam with phenytoin as the drugs of the first choice. Then, barbiturates are given to produce coma. If the disease is progressing, the third choice drugs are also discussed.

Adult↗