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Biomedical subjects

T Dragan

Publications and source records attributed to T Dragan.

13 recordsLinked to original sources
PubMed1998

Determination of furanochromones and pyranocoumarins in drugs and Ammi visnaga fruits by combined solid-phase extraction-high-performance liquid chromatography and thin-layer chromatography-high-performance liquid chromatography.

A new, simple and rapid solid-phase extraction method for the determination of furanochromones and pyranocoumarins in Ammi visnaga L. fruits and pharmaceuticals by reversed-phase high-performance liquid chromatography (RP-HPLC) was developed. The isolation of compounds examined was carried out on octadecyl BakerBond SPE columns using various concentrations of methanol, acetonitrile and tetrahydrofuran in water. High and reproducible recoveries were obtained. To compare the results of quantitative analysis a preparative TLC procedure was also elaborated and carried out.

Antineoplastic Agents↗
PubMed1992

[Surgical treatment of cerebral hematoma using an endoscopic method].

In the period from January 1990 to March 1991 in the Neurosurgery Department, Mining Industry Health Service Hospital in Sosnowiec 21 operations of evacuation of supratentorial intracranial haematomas were carried out by the endoscopic method using a neuroendoscope produced by K. Storz. The indication to this operation was a serious condition of the patients up to 10 points of the Glasgow scale, strictly limited extent of haematoma and ventricular system shifting over 5 mm in computed tomography. The mass of the haematoma could be evacuated in 70-90% and the patients were spared extensive craniotomy. Two patients had reoperations due to renewed haematoma formation. 48% of the patients left the hospital in good condition without neurological deficits and 42.5% had focal neurological signs.

Adult↗
PubMed1992

[[Microsurgical treatment of cerebral hemangioma].

The authors present the results of microsurgical treatment of 16 patients with intracranial arteriovenous malformations. The applied technique made possible considerable sparing of healthy brain tissue and closing feeders closely to haemangioma. The patients in I to III degree according to Spetzler's scale left the hospital in good condition. The patients in IV and V degree in 4 cases were operated on twice and in control examination have presented mild neurological dysfunction. Severe disability was observed only in 1 patient. Control angiography revealed in 3 of these patients the presence of small parts of haemangioma.

Adolescent↗
PubMedDate not supplied

[Risk of hemorrhage and size of hematoma in patients with cerebral arteriovenous malformations].

The occurrence of intracranial haemorrhage, epileptic seizures and focal neurological signs was estimated in the group of 40 patients with AVMs. Size of AVM, its localization was established by angiography. Maximum diameter of a haematoma was measured on preoperative CT. We found that small AVMs (diameter < 3 cm) are more often the source of intracranial haemorrhage than larger ones. Intracerebral haematoma was the larger the lesser was AVM. Intracerebral haematoma has no influence on immediate and long-term results of operative treatment of AVMs.

Adolescent↗
PubMedDate not supplied

[Aneurysm within the optic nerve. Case report].

In a group of 65 aneurysms of the anterior communicating artery treated in the years 1977 to 1984 in the Department of Neurosurgery, Medical Academy in Katowice in one case the aneurysm had an atypical situation penetrating into the optic nerve. A similar case of an aneurysm of the internal carotid artery was reported in the Polish literature only by Tokarz et al. in 1977.

Adult↗
PubMedDate not supplied

[Surgical treatment of a giant aneurysm of the middle cerebral artery].

Four patients with giant aneurysms of the middle cerebral artery over 2.5 cm in diameter were treated surgically. The aneurysms were excised during operations carried out under hypotension achieved with sodium nitroprusside, with administration of large amounts of mannitol and with arrest of blood flow in the middle cerebral artery for 3-10 minutes. Two patients had reoperations for postoperative complications. After the operation the patient who was initially in grade III of Botterell's scale died, and three other patients were in a good condition after one years with moderate paresis of the upper extremity.

Female↗
PubMedDate not supplied

[Spontaneous resorption of an epidural hematoma. Description of 2 cases].

Two patients with subacute epidural haematomas without shifted ventricular system are described in whom the diagnosis was made by computer tomography 8 and 9 days after trauma. Both patients were treated successfully checking the progress with computer tomography and using agents reducing brain oedema.

Adult↗
PubMedDate not supplied

[Intracranial hemorrhages in patients with renal polycystic degeneration].

A female patient is described in whom symptoms of cholecystitis developed after operation for intracranial aneurysm. Enlarged polycystic kidney was recognized erroneously as gallbladder and this error led to laparotomy. In another case meningocerebral haemorrhage developed in a hypertensive patient with polycystic kidney degeneration.

Adult↗
PubMedDate not supplied

[Application of alteplase in prevention of cerebral vasospasm and its sequelae in patients after aneurysmal subarachnoid hemorrhage from ruptured cerebral aneurysm].

15 patients after SAH from ruptured cerebral aneurysm were operated on within 72 hours after SAH. During the operation after clipping of aneurysm 10 mg of rtPA was administered into basal cisterns, Control group consisted of patients who did not receive rtPA. All the patients on the basis of CT scan were classified to III grade according to Fisher's classification. Control CT scan revealed dissolution of most clots in basal cisterns. In comparison with control group the patients who received rtPA rarely experienced radiological signs of vasospasm and delayed neurological deficit.

Adult↗
PubMedDate not supplied

[Two cases of colloid cysts of the third ventricle with nasal rhinorrhea].

The authors present 2 cases of tumours of third ventricle with intracranial hypertension and cerebrospinal fluid rhinorrhea. The cause of the CSF rhinorrhea most often was thinning of lamina ethmoidalis and dura mater and rarely intussusception of arachnoidea into the intrasellar space in patients with oval orifice for the stalk of pituitary body due to prolonged intracranial hypertension. Efficacious treatment of CSF rhinorrhea comprises not only removing of the tumor but also introducing the valve and in some cases tightening of the base of the anterior and middle fossa.

Adult↗
PubMedDate not supplied

[A case of acoustic neurinoma in a girl aged 13].

A 13-year-old girl with large richly vascularized acoustic neurinoma is reported. The family history and clinical evidence failed to suggest neurofibromatosis in the family. The clinical syndrome included paroxysmal headaches, vertigo, loss of consciousness and left ear hearing loss. The application of Nd-YAG laser during the operation reduced bleeding and enabled radical removal of the tumour.

Adolescent↗