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Biomedical subjects

T E Acers

Publications and source records attributed to T E Acers.

18 recordsLinked to original sources
PubMed1994

Adult expression of DeMorsier syndrome following head trauma.

DeMorsier syndrome is a well-described entity, which includes optic nerve hypoplasia and absence of the septum pellucidum with or without pituitary abnormalities. Patients with all three aspects of this syndrome are diagnosed in childhood due to their neuroendocrine dysfunction. We present a review of the literature and a case report of an adult diagnosed with DeMorsier syndrome when he developed neuroendocrine abnormalities after head trauma.

Adult↗
PubMed1994

Incidence patterns of immunogenetic diseases in the North American Indians.

Epidemiologic studies have defined a number of disease susceptibility patterns based on host-environment interaction. The antithetical approach of studying disease resistance patterns has been utilized less frequently. This preliminary data report describes the incidence of certain immunogenetic diseases in North American Indians for "internal comparison" of tribal population groups residing in disparate geographic areas and for "external comparison" with incidence patterns of Caucasian populations residing in the same geographic areas. The preliminary nature of the data precludes any conclusionary statements.

Arthritis, Rheumatoid↗
PubMed1982

Oculomotor-corpus callosum dysplasia.

An infant with congenital bilateral ophthalmoplegia with levator and pupillary sparing is presented. The eyes are fixed in a divergent position with no apparent motility. The baby is otherwise clinically normal and is developing in a normal fashion except for delayed growth pattern. Visual attention is present and he fixates with either eye. Computed tomography demonstrates an associated dysplasia of the corpus callosum and an abnormal ventricular system. Neuroendocrine studies performed at one year of age demonstrate subnormal levels of growth hormone. It is postulated that this represents an embryodysgenesis involving the developing mesencephalic tegmentum (oculomotor nuclei) and the diencephalic lamina reuniens (corpus callosum). It is the first reported case of congenital ophthalmoplegia with corpus callosum dysplasia. The "embryodysgenic" relationship with other forebrain-ocular anomalies has been alluded to and remains speculative.

Adult↗
PubMed1981

Optic nerve hypoplasia: septo-optic-pituitary dysplasia syndrome.

Forty-five patients with the common clinical factor of optic nerve hypoplasia are analyzed regarding their clinical appearance, echographic and computed tomographic measurements of the optic nerves, and the correlation of anatomic size with visual function. Computed axial tomographic studies of the midline brain were performed on all 45 patients to determine the incidence of correlated structural defects, especially the septum pellucidum, and neuroendocrine dysfunction. Review of the spectrum of septo-optic-pituitary syndrome is separately developed to include historical background, embryogenesis, histopathology, and pathogenesis of the three major components of the syndrome. In summary, 45 patients had optic nerve hypoplasia, 32 with evidence of segmental or partial hypoplasia and 13 with evidence of complete or diffuse hypoplasia--the optic nerve hypoplasia syndrome. Twelve of these patients demonstrated absence of the septum pellucidum by computed axial tomography--the septo-optic dysplasia syndrome. Of these 12 patients with partial or complete absence of the septum pellucidum, six demonstrated evidence of pituitary hypofunction--the septo-optic-pituitary dysplasia syndrome.

Adolescent↗
PubMed1981

Focal choroidal calcification.

Localized choroidal calcification was detected clinically in two otherwise healthy men. The lesions showed typical features of choroidal nevi. One patient exhibited features suggesting a drusen overlying the nevus. Echography detected choroidal calcification in both cases. A-scan echography revealed a highly reflective choroidal mass attenuating the ultrasound beam. B-scan ultrasonography revealed a dense choroidal mass attenuating the ultrasound beam with focal echoes remaining at low sensitivity. Orbital radiographic and CT scan examination confirmed the echographic findings.

Adult↗
PubMed1981

Which pathologic characteristics influence echographic patterns of retinoblastoma?

Disagreement still exists regarding the influence of rosette formation, pseudorosettes, necrotic changes, vascularity, and calcification on the echographic characteristics of retinoblastoma. To further evaluate the echographic pattern of retinoblastoma confirmed by tissue diagnosis, we studied 11 consecutive cases of retinoblastoma and correlated pathologic findings with A- and B-scan echographic findings. In five patients with heavily calcified tumors, the A-scan echograms were more accurate in documenting reflectivity and revealed an extremely highly reflective pattern attenuating the ultrasonic beam substantially and casting characteristic shadows on the sclera. The B-scan echogram revealed a mass attenuating the ultrasound beam. This mass had dense focal echoes persisting at lower sensitivity within the tumor. In five patients with mild calcification on pathological examination, the A-scan echogram showed a highly reflective pattern. In one case with no calcification, the A-scan echogram revealed a medium reflective pattern. The B-scan echogram revealed a well-defined mass in each case. The degree of rosette differentiation, pseudorosettes, or necrosis failed to correlate with A-scan echographic pattern specific for retinoblastoma. No case showed a cystic appearance on B-scan echogram regardless of the degree of necrosis seen in the pathologic specimen. The echographic findings in retinoblastoma depend primarily on the degree of calcification and are not influenced independently by other specific pathologic characteristics of the tumors.

Calcinosis↗
PubMed1979

Fusarium oxysporum endophthalmitis.

A 27-year-old man sustained a thorn injury to his left eye and a culture-proven Fusarium oxysporum endophthalmitis developed. This was successfully treated with a vitrectomy, intravitreal and intravenous amphotericin B, and oral flucytosine. The patient maintains 20/20 vision at this time in his left eye. We recommend combined therapy for this filamentous fungal infection.

Adult↗
PubMed1979

Pseudo-orbital apex syndrome.

A 48-year-old man had symptoms and signs of the orbital apex syndrome. All orbital and systemic studies were unrevealing . The computed tomoggraphy scan showed a cystic lesion external to the pons. The lesion proved to be a cholesteotoma originating in the peduncular fossa area, comprising the oculomotor nerve proximally and extending anteriorly in a finger-like projection to involve the ipsilateral optic nerve.

Cranial Nerve Neoplasms↗
PubMed1979

Ocular myasthenia gravis mimicking pseudointernuclear ophthalmoplegia and variable esotropia.

A 70-year-old man with known vascular disease, who had bilateral internuclear ophthalmoplegia, and an 18-month-old girl with a long-term variable esotropia culminating in a postinfectious oculopharyngeal neuropathy both responded with a positive edrophonium chloride (Tensilon) test, strongly suggesting the diagnosis of myasthenia gravis. Both subsequently received maintenance doses of neostigmine methylsulfate (Prostigmin).

Aged↗
PubMed1977

Regression of orbital hemangioma detected by echography.

Two infants had orbital cavernous hemangioma that showed impressive regression documented by ultrasound follow-up. In a 15-week-old infant the hemangioma regressed from a size of 11.49 mm to 5.36 mm in prominence during a six-month period. In a 9-month-old infant the mass regressed from 8.53 mm to 4.6 mm during a six-month period. These cases demonstrate that orbital cavernous hemangioma in infancy occasionally shows impressive regression. Furthermore, they illustrate the value of orbital ultrasonography in defining the natural history of orbital hemangioma. Similar follow-up studies in large numbers of infants with orbital hemangioma are needed to further our understanding of the natural history of this tumor.

Female↗
PubMed1975

Chiasmatic arachnoiditis and empty sella: report and discussion of a case.

The case is presented of a 5-year-old boy with progressive visual loss and physical findings suggestive of pituitary dysfunction. A craniotomy revealed opticochiasmatic arachnoiditis and empty sella. The concomitance of these conditions has not been reported. Both entities are associated with arachnoid cysts or cyst-like swellings of the arachnoid, according to the literature. It is proposed that a primary arachnoid cyst may have displaced the pituitary in the sella resulting in secondary inflammatory responses which affected the chiasm. An alternate, but similar explanation, would involve a perichiasmatic arachnoiditis of unknown cause resulting in cystic invasion of the sella. Rupture of the presumed cyst is believed to have occurred late in the preoperative course, and to have been responsible for aggravation of the symptoms.

Age Factors↗