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T E Deuson

Publications and source records attributed to T E Deuson.

2 recordsLinked to original sources

Percutaneous abdominal biopsy: cost-identification analysis.

PURPOSE: To determine the difference in cost to providers of percutaneous abdominal biopsy as the first strategy versus surgical biopsy. MATERIALS AND METHODS: Cost of tissue diagnosis determination with percutaneous biopsy as the first strategy in 439 patients with an abdominal mass was estimated. Costs included direct hospital costs and professional costs of initial and repeat biopsy, follow-up imaging and clinic visits, surgical biopsy (when needed), and treatment of complications. The sum of these costs was compared with the estimated cost had the same patients undergone surgical biopsy instead, with no complications or need for follow-up or repeat biopsy. RESULTS: The total estimated cost of percutaneous biopsy as the first strategy ($543,245) was less than the cost had surgical biopsy been used alone ($1,919,867). The average per patient direct hospital cost of percutaneous biopsy ($800) was lower than that of surgical biopsy ($3,419). The average per patient professional cost of percutaneous biopsy ($438) was also lower than that of surgical biopsy ($955). Savings averaged $3,136 per patient, or $1,376,622 for the study period. CONCLUSION: Substantial health care cost savings may result by using a diagnostic algorithm in which percutaneous biopsy is the first strategy for establishment of a diagnosis in patients suspected of having abdominal malignancy.

Abdominal Neoplasms↗

Effects of blood and crystalloid cardioplegia on adrenergic and myogenic vascular mechanisms.

BACKGROUND: This study compares the effects of cold blood and crystalloid cardioplegia on adrenergic and myogenic regulation of the coronary circulation. METHODS: Pigs were placed on cardiopulmonary bypass and hearts were arrested with a hyperkalemic crystalloid cardioplegic solution (Cryst CP) or blood cardioplegic solution (Blood CP) for 1 hour. Hearts of selected pigs were then reperfused for 1 hour (Rep) and separated from cardiopulmonary bypass. Left ventricular perfusion and contractility and beta- and alpha 2-adrenergic and myogenic responses of the coronary circulation were examined. RESULTS: Relaxation of isolated, precontracted microvessels to isoproterenol (beta-adrenoceptor agonist) was reduced to a lesser extent after Blood CP as compared with Cryst CP. Relaxation to forskolin (adenylate cyclase activator) was reduced after Cryst CP, but was preserved after Blood CP. After 1 hour of postcardioplegia reperfusion, the respective responses to isoproterenol and forskolin were similar in vessels from the Cryst CP-Rep and Blood CP-Rep groups. The alpha 2-adrenoceptor-mediated, endothelium-dependent vascular relaxation to clonidine was decreased more after Cryst CP than after Blood CP. The relaxation to nitroprusside was not affected by either Cryst CP or Blood CP. Myogenic tone was decreased to a lesser extent after Blood CP versus Cryst CP. Baseline coronary blood flow, isoproterenol-induced increases of coronary blood flow, and indices of myocardial contractility were similar in the Blood CP-Rep and Cryst CP-Rep groups, both 5 and 60 minutes after initiation of reperfusion. CONCLUSIONS: Although Blood CP was superior to Cryst CP in preserving beta- and alpha 2-adrenoceptor function and myogenic tone in vitro, there was no demonstrable benefit of blood cardioplegia in the preservation of myocardial contractility or perfusion in this model of cardioplegia.

Animals↗