Suppurative tissue reaction in a patient with disseminated Mycobacterium avium-intracellulare infection.
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Biomedical subjects
Publications and source records attributed to T E Mason.
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Primary neoplasms of the heart are rare and difficult to diagnose prior to surgery, even with modern imaging techniques. Often, the tumors are diagnosed only at autopsy. Angiosarcoma is the most common malignant neoplasm. This disease is most commonly found in middle-aged men, and the tumor is most often located in the right atrium. It commonly causes blood flow abnormalities, extensively infiltrates cardiac structures, and may extend through the heart wall to involve adjacent structures. Metastatic spread at the time of diagnosis is common, and surgical mortality is high. We present a case of primary angiosarcoma involving the right ventricle of the heart. This tumor developed 6 months after the patient had undergone coronary artery bypass surgery. The patient was initially thought to have a massive thrombus within the right ventricle but at surgery was found to have a malignant neoplasm invading the myocardium. Subsequently, he was found to have pulmonary metastases. A debulking procedure was performed, and the patient was started on chemotherapy. Rather prompt improvement occurred after the debulking procedure, but subsequent studies have indicated progression of the pulmonary metastases despite ongoing chemotherapy.
An unidentified Babesia sp. which causes a mild disease in cattle was isolated in a splenectomized ox that received pooled blood from field cattle. That this organism is pleomorphic and resembles Babesia occultans makes it difficult to differentiate between these organisms microscopically. Initially, it was suspected that this Babesia could be B. occultans. Several attempts to transmit this parasite transovarially with Hyalomma marginatum rufipes, the vector of B. occultans, failed. Continued efforts to identify possible vectors, using Boophilus microplus, Rhipicephalus evertsi evertsi and Rhipicephalus appendiculatus, all failed. The only tick thus far identified that could have transmitted the infection transovarially in the adult stage was the two-host tick Hyalomma truncatum.
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A strain of Babesia bovis that had been attenuated by rapid syringe passage through a series of 23 splenectomized calves was unable to infect its vector Boophilus microplus. An attempt to transmit the attenuated Australian Babesia bigemina G strain with a South African strain of B. microplus was likewise unsuccessful. The epidemiological implication of these observations in terms of babesiosis control is discussed.
A case of ectopic pancreas in the fallopian tube is reported. This small, polypoid, benign tumor was in a fallopian tube contralateral to a ruptured tubal pregnancy. The patient had a tubal ligation performed six years previously. To the best of our knowledge this is the first reported case of isolated ectopic pancreas in a fallopian tube. No explanation is offered for the pathogenesis of this lesion.
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