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Biomedical subjects

T Effenberger

Publications and source records attributed to T Effenberger.

6 recordsLinked to original sources
PubMed1989

Advanced gastric cancer: a new combined surgical and oncological approach.

Forty-two patients with advanced gastric carcinoma underwent chemotherapy in accordance with the FAMTX protocol. Complete tumor remission was achieved in 7%, and partial remission in 29% of the patients. In this group 6 patients (tumor stage: T3-4, N 2-3, M X-1) underwent a second-look operation after chemotherapy either to confirm the complete remission or the resect the remaining tumor mass. The mean follow-up time of these 6 patients is 22 (8-55) months; 4 are still in complete remission 8 to 55 months after the first operation. It is concluded that even in advanced stages of gastric carcinomas a more aggressive approach involving a combination of surgical and chemotherapeutic treatment improves the survival time of these patients.

Adult↗
PubMed1988

[Assessment of specific indicators for determining postoperative infectious complications].

The acute-phase proteins CRP, haptoglobin, and sialic acid of 312 surgical patients (159 females and 153 males), aged between 18 and 95 years, were examined with a view to finding parameters for early prediction of perioperative septic complications. Laboratory tests were additionally applied to 39 patients for activated lymphocytes as well as for OKT3-, OKT4-, and OKT8-labelled T-lymphocytes. Straight forward postoperative decline in absolute numbers of OKT3- and OKT4-labelled T-lymphocytes was recordable from patients with septic complications, in contrast to patients with uneventful clinical courses. However, the OKT4 and OKT8 ratio did not yield any correlation with the clinical course. In acute-phase protein testing, a correlation was found to exist between CRP and clinical course. CRP levels in patients without septic complications (Group I) were found to depend clearly on the anatomic site of surgery. Normalisation of CRP levels was recordable from patients with primary septic disease and complete surgical management of the focus (Group II/1). Postoperative decline of CRP values was much less in patients with primary septic disease and incomplete surgical treatment (Group II/2). They had not even reached normality towards the end of observation. On average, unambiguously increased values were recordable as early as three days prior to clinical manifestation from patients with postoperative septic complications (Group III). Septic complications were found to occur along with re-increase or delayed decrease of CRP levels, after the fourth postoperative day. Sensitivity amounted to 78 per cent and specificity to 89 per cent.

Acute-Phase Proteins↗
PubMed1988

[Chloramine T solution for intraoperative peritoneal lavage. A statistical analysis].

An analysis and statistical evaluation of 1,157 cases of wound healing produced evidence to the effect that the rate of wound healing disorders could be substantially reduced by prophylactic peritoneal lavage, using 0.1 per cent chloramine-T solution. That reduction was from nine to 2.6 per cent in the author's cases. - In the context of perforations (n = 186), therapeutic peritoneal lavage, using chloramine-T, proved clearly superior to washing with physiological salt solution in coping with wound healing disorders. Here, the rate of such disorders was reduced from 22.4 to 8.3 per cent, and it dropped further to 4.5 per cent in those cases of perforation in which additional lavage was applied to the surgical wound proper.

Abdomen↗
PubMed1984

[Gastric surgery in the aged].

Because of continuous progression of age surgery of the aged has become a main problem especially in gastric surgery. 282 cases of more than 70 years old patients undergoing gastric operations between 1964 and 1981 are analyzed. There is a majority of emergency operations (62%), only 16% of the ulcer operations were elective. This caused a high mortality rate (total over 40%) compared with 10% in the elective group. Better results could be obtained by a higher elective rate, i.e. earlier diagnosis.

Age Factors↗