PubMed Health⌕ Search

Biomedical subjects

T Enoki

Publications and source records attributed to T Enoki.

At least 55 records · Page 3Linked to original sources

[Polymorphonuclear leukocyte elastase (PMNE) levels in surgical patients with postoperative infections].

To study the role of lysozomal enzyme released from polymorphonuclear leukocytes during postoperative infections, plasma levels of PMNE were measured serially in 53 patients who underwent digestive surgery. The patients were divided into two groups, 18 patients with postoperative infections (infected group), and 35 patients without infections (non-infected group). The PMNE levels in the non-infected group elevated during one week with peak value in one postoperative day, but returned to preoperative levels in two weeks. The levels of fibronectin (FN), C3, C4 and antithrombin III (ATIII) were decreased after surgery, but returned within seven postoperative days. On the contrary, the PMNE levels in the infected group remained high two weeks after operations and elevated higher than those of non-infected group before clinical signs of infections. In infected group, the levels of FN and ATIII were significantly decreased two weeks after surgery, compared to those of non-infected group. Correlations were demonstrated between the amount of PMNE and the decrease in the levels of FN and ATIII. It is suggested PMNE might play a role in the pathobiochemical alterations including of acceleration of coagulation during postoperative infections. The measurement of the levels of PMNE in the postoperative course seems to be an useful index to early diagnosis of postoperative infections.

Aged↗

[Electrocardiogram in pulmonary heart disease--clinical evaluation of right chest leads].

A clinical study was made to evaluate the usefulness of electrocardiograms in right precordial leads (V3r or V4R) for the diagnosis of cardiac complications among patients with chronic pulmonary disease. Walsh and colleagues reported that the change of direction in the terminal vector of QRS loop in the vector cardiogram is useful for the evaluation of chronic pulmonary heart disease. They showed that the terminal vectors of QRS loops tend to deviate to the right and/or posterior direction in the early stage of chronic pulmonary heart disease. We utilized the electrocardiograms in the right precordial leads to detect the second R waves, which are thought to reflect the terminal vectors of QRS loops in the vectorcardiograms. When the electrocardiograms in the right precordial leads were compared, the second R waves in leads V3R or V4R were more frequently observed among patients with chronic pulmonary heart disease than those without. However, in the same two groups, the frequency of second R waves in leads V5R or V6R didn't differ. We conclude that the second R waves in leads V3R or V4R in a patient with chronic lung disease suggest the presence of chronic pulmonary heart disease as a complication.

Adult↗

Analysis of second-order kernel response components of multifocal electroretinograms elicited from normal subjects.

PURPOSE: It has been reported that the second-order kernel response components of multifocal electroretinograms (mERGs) reflect the electrical activity of the inner retinal layers. In this study, we have investigated whether the amplitudes of the second-order kernel response components correlate with the spatial distribution of human retinal ganglion cells. METHODS: Multifocal electroretinograms were recorded using the Veris III system from 5 healthy subjects with different stimulus and recording parameters. The mERGs were analyzed using the Veris Science software programs. The stimuli consisted of densely arranged arrays of 103, 61, 37 or 19 hexagonal elements. Four minutes were required to record one set of mERG responses using 8 sessions, and 8 minutes using 16 sessions. The second-order kernel response components were extracted and analyzed using the Veris Science program. RESULTS: The signal-to-noise ratio of the first-order kernel response components was improved considerably by the summation of the nine reproducible responses from the same subject but the second-order kernel response components were not. The summation of the nine reproducible responses was insufficient to identify an array of the second-order kernel response components. Both the first- and second-order kernel response components were larger when fewer hexagonal elements were used. There was no significant difference in the individual responses between the 4-minute and the 8-minute recordings. A response density analysis revealed a weak correlation between the amplitude distribution of the second-order kernel response components and the spatial distribution of human retinal ganglion cells. CONCLUSIONS: The distribution of the amplitudes of the second-order kernel response components of the mERGs elicited from normal subjects did not correlate with the distribution of human ganglion cells. This suggests that the theory that second-order kernel response components arise from the activity of retinal ganglion cells should be reconsidered.

Adult↗