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Biomedical subjects

T F Bader

Publications and source records attributed to T F Bader.

7 recordsLinked to original sources
PubMed1996

Hepatitis A vaccine.

Hepatitis A continues to cause sporadic cases, epidemics, and occasional deaths in the United States. A killed virus vaccine for immunization against hepatitis A has recently been approved by the Food and Drug Administration. One hundred percent seroconversion occurs after a series consisting of a primary dose and a second booster shot 6-12 months later. Co-administration of immune-globulin and hepatitis A vaccine lowers ultimate antibody levels 50% compared with vaccine alone. Targets for immunization will probably be children, international travelers, military personnel, and food handlers. It will also be useful for general vaccination in areas where smoldering epidemics occur. Natural immunity levels in the United States population have undergone a significant decline since 1980 and are currently in the 21-33% range. Prescreening for immunity is likely to be cost-effective in persons over age 40.

Adolescent↗
PubMed1988

Extrahepatic hepatocellular carcinoma metastasis demonstrated by technetium-99 HIDA scan.

A patient presented with a 10-cm mass in the left lobe of the liver. Liver biopsy revealed hepatocellular carcinoma with abundant bile staining. A chest roentgenogram showed a 13-mm nodule in the right mid-lung field. A 99Tc HIDA scan was ordered for the evaluation of the pulmonary nodule. Intense uptake of the radionuclide was noted in the location of the nodule. The findings in this case suggest that the 99Tc HIDA scan may be a useful staging agent after the diagnosis of hepatocellular carcinoma has been documented.

Carcinoma, Hepatocellular↗
PubMed1986

Colorectal cancer in patients older than 75 years of age.

Two hundred and seven hospital records of patients with colon or rectal cancer from 1982 to 1985 were reviewed retrospectively. Ninety-six patients were 75 years of age or older and 111 were younger than 75 years. Comparison of the two groups showed that the elderly group presented with lower hematocrits and serum albumin values despite comparable pathologic stages and tumor location. A higher preanesthetic stage was seen in the elderly group. The total perioperative mortality rates for the young and elderly groups were 3.6 percent and 7.1 percent, respectively, and were not statistically different. Emergency perioperative mortality rates were 5.2 percent and 10 percent, respectively, and also were not statistically different. All nine patients aged 90 and older underwent a major abdominal operation without the occurrence of any perioperative mortality. This study suggests that age need no longer be considered a major risk factor for immediate surgical outcome in colorectal cancer.

Age Factors↗
PubMed1986

Hepatitis B in prisons.

Prisoners have been thought to be at high risk of contracting hepatitis B. Prevalence studies throughout the world show a similar hepatitis B marker rate of 28 to 51%. Seroconversion studies have shown a 0.8 to 1.4% incidence in male prisoners. These results are far less than the predicted 5 to 10% annual attack rate for a similar non-incarcerated population. Cost considerations prevent universal vaccination of prisoners, but IV drug abusers and female prisoners seem to be at especially high risk and should be targeted for immunization now. Prisoners who are chronic carriers of HBsAg and who are also "e" antigen positive or delta antibody positive should be segregated.

Carrier State↗