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Biomedical subjects

T F Doran

Publications and source records attributed to T F Doran.

6 recordsLinked to original sources

Atopic disease, rhinitis and conjunctivitis, and upper respiratory infections.

In this section, we review three broad topics in pediatrics: atopic disease, rhinitis and conjunctivitis, and upper respiratory tract infections. These topics comprise three of the most commonly encountered problems in pediatric practice. There have been significant contributions to the pediatric literature in each of these areas over the past year, and we review those of particular interest here. The papers that we have chosen to review were selected for both their scientific significance and practicality. Both review articles and original research are included, but all should be relevant to the care of your patients.

Asthma↗

Atopic disease, rhinitis and conjunctivitis, upper respiratory tract infections, and insect stings and snake bites.

In this section we review four broad topics in pediatrics: atopic disease, rhinitis and conjunctivitis, upper respiratory tract infections, and insect stings and snake bites. The first three topics comprise three of the most commonly encountered problems in pediatric practice. Although the fourth topic accounts for a relatively small number of office visits, it generates a great deal of concern among our patients and their parents. There have been significant contributions to the pediatric literature in each of these areas over the past year and we review those of particular interest here. The papers that we have chosen to review were selected for both their scientific significance and practicality. Both review articles and original research are included, but all should be relevant to the care of your patients.

Adolescent↗

Atopic disease, rhinitis and conjunctivitis, upper respiratory tract infections, and insect stings and snake bites.

In this section we review four broad topics in pediatrics: atopic disease, rhinitis and conjunctivitis, upper respiratory tract infections, and insect stings and snake bites. The first three topics comprise three of the most commonly encountered problems in pediatric practice. Although the fourth topic accounts for a relatively small number of office visits, it generates a great deal of concern among our patients and their parents. There have been significant contributions to the pediatric literature in each of these areas over the past year and we review those of particular interest.

Bites and Stings↗

Acetaminophen: more harm than good for chickenpox?

STUDY OBJECTIVE: To determine whether acetaminophen affects the duration or severity of childhood varicella. DESIGN: Randomized, double-blind, placebo-controlled trial. SETTING: Office- and hospital-based pediatric practices. PATIENTS: Seventy-two children between 1 and 12 years of age entered the study. One child was withdrawn because of high fever, and three children did not complete the study; 31 received placebo and 37 received acetaminophen. INTERVENTIONS: Acetaminophen, 10 mg/kg/dose, was given at 8 AM, 12 PM, 4 PM, and 8 PM for 4 days. Placebo was given to the control group. Itching, appetite, activity, and overall condition were measured for 6 days. The time to last vesicle formation, time to total scabbing, and time to total healing were measured until complete resolution of the exanthem. MEASUREMENTS AND MAIN RESULTS: The following results were better in the placebo group (p less than .05): time to total scabbing 5.6 days (SD 2.5) versus 6.7 days (SD 2.3) in the acetaminophen group, and itching on day 4 in the placebo group (symptom score 2.9 (SD 0.20) vs 2.2 (SD 0.26]. Activity was better in the acetaminophen group on day 2 (3.13 (SD 0.23) vs 2.82 (SD 0.24]. CONCLUSIONS: These results provide evidence that acetaminophen does not alleviate symptoms in children with varicella and may prolong illness.

Acetaminophen↗