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Biomedical subjects

T F Sokolova

Publications and source records attributed to T F Sokolova.

At least 19 recordsLinked to original sources

[The involvement of the components of the immune system in iron deficiency].

As exemplified by iron deficiency anemia, the study was made of effect of iron deficiency on interdependence of immunity parameters. It is noted that patients with definite forms of the anemia showed less numerous correlations than in controls. The emergence of complications increased the number of persistent correlation pleiad compared to controls. Moreover, correlation and variance analyses suggested a correlation between immunity and iron deficiency parameters.

Adolescent↗

[Clinico-immunological parallels in patients with iron-deficiency anemia].

The main parameters of humoral and cellular immunity as well as indices of nonspecific body resistance were studied in 70 patients with iron deficiency anemia. A decrease in the content of the main classes of immunoglobulins and an increase in the CIC level were noted. Routine therapy brought about a tendency toward the restoration of indices of humoral immunity. With respect to cellular immunity, a relative increase in the level of B-lymphocytes and a decrease in the number of 0-lymphocytes were observed. A relative and absolute decrease in the level of T-helpers was revealed. Certain correlation between some clinical and immunological indices was observed.

Adult↗

[Effect of hemosorption on the level of medium molecular mass polypeptides and humoral immunity in patients with peritonitis].

An examination of 43 patients with acute diffuse peritonitis of various etiology has revealed different direction of the dynamics of indices of humoral immunity (M, G, A immunoglobulins, general complement activity, circulating immune complexes) depending on the level of middle mass polypeptides (MMP) in the patient's blood. Hemosorption in peritonitis was established to allow rapid and effective elimination of MMP in patients with high content and thus control critical endotoxicosis.

Acute Disease↗

[Insulin-depositing function of peripheral blood erythrocytes in rats that have sustained severe craniocerebral injury].

Rats with a grave craniocerebral injury were examined over time for the content of insulin in red cells (1, 3, 7, 14, 21 and 35 days after injury). Alterations were found in the affinity of circulating red cells for paraaldehyde fuchsin (PAF), linked primarily with a decrease in the proportion of the PAF-resistant forms of the cells. It is suggested that in general the data obtained reflect the intensification of the receptor function of the red cell membrane.

Acute Disease↗

[Prognostic significance of changes in blood morphology in severe trauma].

The examination of 121 patients with traumas of adaptation reactions by morphological parameters of the white blood has shown them to be indices of non-specific resistance of the organism elucidating the degree of the compensatory-adaptative processes. The parameters in question may be used as subsidiary criteria for prognosis of the course of the traumatic disease.

Adaptation, Physiological↗

[Effect of rations with a varying content of polyunsaturated fatty acids and vitamins on the state of the small intestine in respect of age].

Groups of young sexually mature and old albino rats were kept for three months on 4 isocaloric rations, viz. balanced, with reduced proportion of essential fatty acids or group 'B' vitamins and with simultaneous curtailment of fatty acids and vitamins. With vitamin deficiency there was a certain derangement in the structure and function of the small intestine, especially in older animals. A shortage of essential fatty acids impaired the condition of the small intestine only in old animals. In cases of concurrent deficiency of vitamins and essential fatty acids maximal changes in both young and old animals were in evidence.

Age Factors↗