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Biomedical subjects

T F Vanner

Publications and source records attributed to T F Vanner.

4 recordsLinked to original sources

Ambulatory urodynamics.

Long-term ambulatory urodynamic monitoring has been employed in 20 patients in an attempt to detect detrusor abnormality not appreciated by conventional cystometry. In 9 female patients with the "urge syndrome" it detected 2 previously unrecognised cases of detrusor instability; in 4 enuretic patients, only 1 of whom was known to be unstable previously, unstable contractions were confirmed, and 2 of 7 cystoplasty patients had high amplitude contractions detected only on ambulatory assessment. The technique provides a more sensitive index of lower urinary tract function than conventional cystometry in such patients.

Adolescent↗

Permanent urethral stents for detrusor sphincter dyssynergia.

A series of 22 patients, most of whom had spinal injuries with detrusor sphincter dyssynergia, have had Medinvent Wallstents placed across the distal mechanism. All but 8 patients had undergone outflow surgery and 11 had had repeated unsuccessful sphincterotomies. The proximal end of the stent was placed over the verumontanum unless fertility was contemplated, when it was placed immediately below the verumontanum. Fifteen patients achieved complete voiding after placement of the first stent; 3 developed bladder neck obstruction after stenting, but in 1 of these cases resolution occurred after bladder neck incision. The 3 patients with artificial urinary sphincters failed to improve after stenting. Use of the urethral stent for patients with detrusor sphincter dyssynergia and failed sphincterotomy is a major advance. It should probably be the primary treatment in selected cases. Its effect on fertility is currently under assessment.

Humans↗

Assessment of the long-term results of subtrigonal phenolisation.

Long-term follow-up was conducted on 97 patients who had undergone subtrigonal phenolisation for detrusor instability, bladder hypersensitivity, detrusor hyper-reflexia or interstitial cystitis. The procedure failed to alleviate lower urinary tract dysfunction in 57% of patients; it had an unsustained benefit in 24% and long-term success was experienced by only 19%. It was most effective in the hypersensitive bladder of unknown cause. The incidence of complications (17%) suggests that the procedure should only be undertaken if more invasive measures are the only available alternative, and the possibility of these complications should be explained to the patient.

Administration, Intravesical↗

Miniature electronic blood pressure monitor compared with a blind-reading mercury sphygmomanometer in pregnancy.

The use of electronic blood pressure monitors is increasing, but they have received little evaluation in pregnancy. We compared an electronic monitor (Nissei D-175 Digital Monitor) with a London School of Hygiene blind-reading mercury sphygmomanometer in clinical conditions in 41 patients in the third trimester. In 141 comparisons, the electronic monitor read systolic pressures that were 16.53 mmHg higher on average than the mercury sphygmomanometer, the limits of agreement being from -9.13 mmHg to +42.19 mmHg. For diastolic pressures, the electronic monitor read 9.71 mmHg higher on average than the mercury sphygmomanometer, the limits of agreement being from -16.97 mmHg to +36.39 mmHg. The coefficient of repeatability was similar for both instruments with systolic and diastolic readings. As much caution should be exercised with the use of the electronic monitor in late pregnancy as with the mercury sphygmomanometer, and practitioners should be aware of the marked differences that can occur between instruments.

Blood Pressure Determination↗