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Biomedical subjects

T Farkas

Publications and source records attributed to T Farkas.

At least 109 records · Page 6Linked to original sources

[Possibilities of treatment of open fractures of the tibia].

Results of healing in 477 cases of open leg fractures treated in the Central Institut of Traumatology in Budapest are analysed in the article. 47,2% of cases were treated by closed methods. The authors are convinced that careful conservative management leads to good results, if the type of the fracture is suitable. Conditions of operative treatment are outlined. In favourable circumstances a stable internal fixation should be performed, otherwise inramedullary wiring and plaster may hold the fragments until healing occurs. Soft tissues should be handled carefully and placing sutures under tension must be avoided, by all means.

Fracture Fixation, Internal↗

Biosynthesis of fatty acids by the carp, Cyprinus carpio L., in relation to environmental temperature.

Incorporation in vivo of sodium 1-14C-acetate into different lipid classes and fatty acids of total lipids and phospholipids of warm adapted and cold adapted carp livers was studied at 5 C and 22 C, respectively. The fatty acid composition of total lipids and phospholipids was also determined. The level of long chain polyunsaturated fatty acids in both total lipid and phospholipid fraction was higher in cold adapted fish than in warm adapted ones. The distribution of radioactivity among different lipid classes depended only on the actual incorporation of the temperature history of the animals. Livers of fish incorporated a higher percentage of radioactivity into long chain polyunsaturated fatty acids of total lipids and phospholipids in 5 C than in 22 C. The distribution of radioactivity among different fatty acids was dependent on the experimental temperature rather than on the temperature to which the fish were adapted. The results suggest that fish are able to adjust the pattern of the biosynthesis of fatty acids very rapidly to the prevailing temperature and to assure by this way the proper physicochemical properties of their membranes. The possible mechanisms involved in this rapid response are discussed.

Acclimatization↗

Thermoanalytical and histological study of intra-articular papain-induced degradation and repair of rabbit cartilage. II. Mature animals.

The effect of papain treatment on the cartilage tissue of the knee joint of mature rabbits was studied by histological and thermoanalytical methods. Changes taking place in the composition of cartilage in the course of ageing were shown. As a result of papain treatment a significant irreversible destruction of the ground substance took place. Papain-induced loss of proteoglycans and the intensity of repair reactions and age-related differences are discussed.

Aging↗

Treatement of excessive weight gain in patients taking lithium.

Six female primary affective disorder patients who had gained an average of 9.5 kg while taking lithium lost an average of 2.9 kg on a 10-day 900 calorie a day hospital diet containing 100 mEq of sodium per day. No evidence of lithium toxicity was observed on this regimen. There was no evidence that fluid retention played a major role in the weight gain.

Bipolar Disorder↗

L-tryptophan in depression.

L-tryptophan, the amino acid precursor of serotonin, was administered to 16 depressive patients in a double-blind study of its potential antidepressant efficacy. Antidepressant responses were observed in one of ten unipolar patients and in three of six bipolar patients. These results are discussed in the context of possible interactions of amines with electrolyte systems in the etiology of affective illness.

Adult↗