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Biomedical subjects

T Ferri

Publications and source records attributed to T Ferri.

At least 37 records · Page 2Linked to original sources

[Our experience in esthetic and functional surgery of the nose].

The authors report their experiences on functional and aesthetic nose surgery. The patients selection, the pre-operating test are based both on the rhinologic functionality and the photografic studies. Operative techniques are described together with pictures of most important stages. Results are shown with patients pictures before and after intervention.

Esthetics↗

[Reconstructive sub-total laryngectomy according to Labayle. Clinical experience on 21 cases].

In this paper the authors report the functional and oncological results regarding 21 patients suffering from laryngeal carcinoma, who underwent surgery at the University of Parma's ORL Clinic - between 1975 and 1984 - for sub-total reconstructive laryngectomy using the Labayle method. This process provides for not just the radical removal of the laryngeal tumor, but also for restoring basic functions such as respiration, phonation and swallowing. To this end, during the destructive phase, the cricoid cartilage (partially or wholly) and one or both of the arytenoids are retained. The application of this method is situated somewhere between the classic total laryngectomy and the conservative supraglottic, at times finding itself in natural opposition to the expanded supraglottic the lateral-front, the hemilaryngectomy, the crico-ioidopesia and the Serafini-type total laryngectomy. Since it doesn't concern a total laryngectomy in the strict sense of the word, the operation presents general counterindications that are relative - and which exist for that matter in all laryngeal surgery, functional or reconstructive - and local counterindications that are absolute. In addition to the, elective indications are dictated critically. The surgical act, illustrated in detail, consists in a period of approach or preparation, a period of destruction and a period of reconstruction. The results obtained from the series of cases followed are wholly satisfactory from both the functional and oncological point of view: the parameters evaluated - respiration, phonation and swallowing - were totally restored in the majority of cases. Swallowing in just two patients was insufficient, as was respiration in one. Concerning the oncological results, if we exclude 4 cases of the 21 considered which do not have a follow-up of more than three years, there have been no clinical signs of a recurrence of the tumoral disease in the remaining 17, of which 15 have been under observation for more than 5 years. The survival rate, up to the first months of 1985, is 70.5%.

Adult↗

[Laryngeal plasmacytoma. Observations on a clinical case].

Extramedullary solitary plasmocytoma (E.S.P.) is an undoubtedly rare neoplasm for the head and neck areas and even more for the larynx. The Authors take a case observed by them as a starting point for remarking its symptomatology and unforeseable development as well as various and unsteady histopathology. Afterwards they dwell upon the differential diagnosis with the multiple myeloma and the plasmacell granuloma. Such diagnosis is mainly suggested by the histopathological investigation with the support of clinical, blood and radiologic tests. The preferential treatment and the need of a long-term and careful follow-up are the suggested.

Aged↗

[Neurofibroma of the tongue: a clinical case].

The Authors report a case of neurofibroma of the tongue, observed by them. Its peculiarities and the differential diagnosis with neurinoma and other affections are discussed, mostly pointing out its rarity, epidemiological data and histogenesis. After a review of the literature concerning these forms, the Authors dwell upon the histopathologic characters of neurofibroma, the peculiarities of the case reported by them, considering the real rareness of an isolated report of neurofibroma, typical element of Recklinghausen's disease.

Humans↗

[A case of lipoma in a pharyngeal site].

The Authors describe a clinical case of lipoma examined by them in a retropharyngeal site. Reports published in literature show the extreme rarity of a pharyngeal localization of lipomas. The symptomatology and numerous differential diagnoses are examined. Of the instrumental diagnostic examinations, the stratigraphy of the pharynx and CAT were decisive in identifying the benign nature of the neoformation. In the clinical case described, needle biopsy did not produce any decisive diagnostic elements. In agreement with other Authors, the therapy of choice to be followed is a surgical procedure.

Female↗

[Laryngocele. Possibilities and limitations of surgical treatment under direct microlaryngoscopy].

Three cases of laryngocele are reported, which were managed by surgery under direct microlaryngoscopy with excellent clinical and functional results, both at short and long term. According to the classification of Y. Lacomme, two patients had an internal or vestibular laryngocele, which was of the low type in one of them and of the middle type in the other. In the first case the pouch and the false vocal fold lying over it were completely removed under direct microlaryngoscopy. In the second case the laringeal cavity was marsupialized after extensive resection of the false fold and part of the lateral wall of the vestibule. Over a short period of time both patients were symptom-free and eventually recovered completely. In the third case tha laryngocele was of a classic mixed type. The patient, who risked suffocation, was elderly (77 years of age) and extremely debilitated. A few days earlier he had had an emergency tracheotomy for severe respiratory failure. Surgery under direct microlaryngoscopy consisted in removing the false fold and the internal laryngocele. About one and ahalf months later, the tracheostomy opening had closed and the latero-cervical pouch had been gradually reduced. The latter was drained abundantly into the laryngeal lumen and remained as an external laryngocele. When the patient is in good enough condition, the laryngocele will be completely removed by means of the most suitable among the common external-approach surgical techniques.

Adult↗

[Comparative study of pre and post-operative dynamic respiratory indices in subjects undergoing total laryngectomy].

A spirometric measurement was carried out on patients with cancer of the laryn before and after surgery for total laryngectomy at the Istituto Policattedra of the University of Parma ENT Clinic. Postoperative spirometry was performed by means of a Vitalograph apparatus with the mouthpiece positioned right over the tracheal opening. The parameters considered were the dynamic respiratory indices (CV/MEVS - MEVS/CV). Forty patients was mostly based on the fact that, prior to laringectomy, all of them had been subjected to a spirometric measurement for aneasthesiologic purposes. According to the results obtained, the patients can be divided into three groups. The first group consists of 10 subjects in whom no improvement was observed in their MEVS value, which in some instances had actually worsened. The second group is composed of 20 patients in whom the spirometric values remained more or less steady. The third group comprises 20 patients who showed a marked improvement of their respiratory indices. In some of the latter patients the values obtained were even better than those in the normal range. However, the overall average results are not statistically significant, except for an average 9% improvement of MEVS due, as expected, to a reduction of the dead space following total laryngectomy and a corresponding, though very slight, 4% improvement of the Tiffenau ratio.

Aged↗

[Use of the Montgomery prosthesis in the treatment and prevention of anterior commissural synechiae secondary to bilateral cordectomy].

The authors report the results obtained with the use of the Montgomery silicone prosthesis for the prevention or treatment of thick and sometimes partially stenosing synechiae of the anterior commissure following bilateral cordectomy by median thyrotomy. The umbrella-shaped prosthesis consists of two silicone sheets which are perpendicular to each other. The vertical sheet is of variable length and, once placed in position, it separates at the anterior commissure the two portions of larynx operated on, so that they may be adequately reepithelized. This procedure was used in three patients undergoing internal subperichondral cordectomy by median thyrotomy, due to a malignancy in both vocal folds which, however, was not extended to the anterior commissure. In two patients the prosthesis was fitted in during the main surgical procedure to prevent an excess of scar tissue; in the third patient, by contrast, it was used to treat a thick, partially stenosing synechia in the commissure secondary to cordectomy, which had already been unsuccessfully managed under direct microlaryngoscopy. In the three patients the prostheses were left in place for 2 and a half, 3, and 3 and a half months, respectively, with no major irritation or inflammation inside the larynx. No supportive tracheotomy had to be performed, and only in one case was the prosthesis secured externally by percutaneous stitching. On indirect laryngoscopy several months after the prosthesis was removed, two patients showed a perfectly healed larynx; in the third patient a very small amount of scar tissue in excess was still present, but it did not affect his respiratory function.

Adult↗

Selenium speciation in waters: role of dissolved polysaccharides on the mobilization process.

The paper deals with the study of selenium speciation in a water system where antropic contribution could be relevant (Tiber river). The speciation at natural levels was determined before, inside, after the city of Rome by a previously defined method: the tetravalent state is prevalent in the anthropized zone while the highest oxidation state is predominant outside. The study of the storage effects (on a whole sample) and the distribution (fate) of the selenium contribution were also carried out. The study showed how in polluted waters the fraction of dissolved organic matter able to bind Se(IV) highly affects the mobility of selenium in the matrix. Polysaccharide species show this property, so they are be very probably responsible for the adsorption of selenium on particulate and stabilize this form against oxidation.

Adsorption↗

[The glosso-crico-arytenoid unit as a phonatory organ in sub-total reconstructive laryngectomy using the Labayle technic].

The present study was carried out in order to assess characteristics of vicarious voice in patients undergoing Labayle's reconstructive sub-total laryngectomy. This type of surgery, which permits air passage for both respiration and phonation, makes it possible to preserve pneumophonic coordination. During phonation the expiratory air column is used and sound is generated as it passes through a vibrating structure having a sphincteric function. In the opinion of the authors this structure is not only made up of the cricoid orifice, against which the base of the tongue presses like an operculum, but also of the mobile residual arytenoid and, at times, of the lateral walls of the pharynx. Thus a single dynamic unit is formed involving several structures and their synergism guarantees the neoglottic occlusion required for a speaking voice. In the present study, glottography gave no significant results. In phonation a rapid vibration of the neoglottid mucosa is obtained thus producing a phonetically valid acoustic phenomenon. However, this does not result in an electroglottographic recording of adduction. On the other hand, interesting data were recorded when comparing the morpho-functional aspects of the neoglottis with characteristics of the vibrating voice, as recorded by spectrography. Spectrographic tracings are markedly better in cases of valid occlusion of the glosso-pharyngeal-arytenoid unit and this may be achieved regardless of the mobility of the remaining arytenoid. It is thus clear that several patients with a fixed arytenoid, but having valid sphincteric action of the other structures (i.e. base of the tongue or pharynx), had excellent speech quality and intelligibility. Therefore, Labayle's surgery, which reconstructs a pharyngo-tracheal continuity and consequently restores natural breathing, makes speech continuity possible. Such subjects have mixed vocal output (periodic components together with noise) although, on the whole, the voice produced has the fundamental requirements for intelligibility (i.e. intensity, pitch, harmonic structure, emission time) and may thus be considered valid for interpersonal verbal communication.

Arytenoid Cartilage↗