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Biomedical subjects

T Finitzo-Hieber

Publications and source records attributed to T Finitzo-Hieber.

12 recordsLinked to original sources
PubMed1985

Prospective controlled evaluation of auditory function in neonates given netilmicin or amikacin.

Longitudinal assessment of intensive care nursery infants given aminoglycoside antibiotics revealed no significant difference in the incidence of hearing impairment when compared with age- and sex-matched controls. Bilateral sensorineural impairment was confirmed in three (2%) infants, one each given netilmicin and amikacin and one untreated control infant. There was a high incidence of transient auditory abnormalities in this intensive care infant population. These findings emphasize the importance of long-term follow-up hearing evaluations in infants who require intensive care management in the neonatal period.

Amikacin↗
PubMed1984

Abnormal parasympathetic vagal function in patients with spasmodic dysphonia.

Gastric vagal function was assessed in 15 patients with spasmodic dysphonia by measuring gastric acid output in response to sham feeding. Patients secreted significantly less acid than controls (p less than 0.001). Cardiac vagal function was assessed in 11 patients by measuring heart rate during deep respiration and also during and after Valsalva maneuver. Patients with spasmodic dysphonia had a significantly reduced fluctuation of heart rate during deep respiration (sinus arrhythmia). The expiratory to inspiratory R-R interval averaged 1.08 +/- 0.08 (mean +/- SD) in patients and 1.22 +/- 0.10 in controls (p less than 0.005). The ratio of tachycardia during Valsalva maneuver to bradycardia after Valsalva maneuver was also lower in patients than in controls (p less than 0.005). The auditory brainstem response was abnormal in 11 of 15 patients. Our results show either a central brainstem abnormality or several cranial nerve abnormalities in some patients with spasmodic dysphonia.

Adult↗
PubMed1981

Abnormalities of the auditory brainstem response in post-meningitic infants and children.

The auditory brainstem response (ABR) was recorded in 86 infants and children from 1 month to 14 years of age following episodes of bacterial or viral meningitis. Thirty-two demonstrated some degree of cochlear impairment. These was a high incidence of neurological sequellae in these children. Eight children exhibited abnormal changes suggestive of brainstem dysfunction. Six of these eight children also had abnormal neurologic examination. Recovery, or at least improvement in the ABR, occurred in six infants who were assessed upon discharge from the hospital, and then again several months post-hospitalization. In each case improvement was attributed to a resolving conductive component. The ABR was found to be effective for identifying hearing impairment and brainstem dysfunction in pediatric patients following central nervous system infection. Objective information, not available from other methods of assessment was obtained.

Adolescent↗
PubMed1979

Ototoxicity in neonates treated with gentamicin and kanamycin: results of a four-year controlled follow-up study.

This article reports the results of a four-year follow-up study initiated in 1970 on the long-term effects of gentamicin and kanamycin use in newborn infants. Audiometric, vestibular, and psychometric evaluations were performed on gentamicin-treated, kanamycin-treated, and untreated, matched control infants and children. No substantial sensorineural hearing loss or vestibular dysfunction was identified in these patients that could be attributed to aminoglycoside therapy. Performances on the Illinois Test of Psycholinguistic Abilities, Beery Test of Visual Motor Integration, the Peabody Picture Vocabulary Test, and on fine and gross motor examinations were comparable for the three study groups.

Audiometry↗
PubMed1979

Brain stem auditory evoked potentials in patients with congenital atresia.

The purpose of this paper is to illustrate the value of the brain stem auditory evoked response in the definitive assessment of newborn and older infants with congenital malformations of the auditory system. Clinical cases selected illustrate the methodology required in the evaluation and demonstrate how the technique can facilitate immediate and appropriate medical and habilitative services.

Adult↗
PubMed1978

Room acoustics effects on monosyllabic word discrimination ability for normal and hearing-impaired children.

The monosyllabic work discrimination of normal and hearing-impaired children was evaluated in situations selected to simulate acoustical conditions in current educational environments. All listeners were tested in a high-fidelity (loudspeaker-aided) condition under 12 combinations of reverberation and noise. Hearing-impaired subjects were also evaluated in the same 12 conditions while listening through a monaural hearing aid. Performance of the normal-hearing group was superior to the hearing-impaired listeners in all environments. Results suggest that classroom acoustics should be considered a critical variable in the educational achievement of children.

Acoustics↗
PubMedDate not supplied

Auditory brainstem response abnormalities in adductor spasmodic dysphonia.

Six patients with adductor spasmodic dysphonia were evaluated for evidence of brainstem dysfunction using the auditory brainstem response (ABR). In four, abnormally large increments in wave V latencies were found at high stimulus repetition rates. Latency increments exceeded three standard deviations above the mean in a normative adult population. A fifth patient had the prolonged interpeak latencies described previously by other investigators. In five of six patients the capacity of the auditory brainstem to conduct impulses was compromised. These results suggest a central nervous system abnormality in adductor spasmodic dysphonia.

Adult↗
PubMedDate not supplied

A sound effects recognition test for the pediatric audiological evaluation.

In this paper, we describe the development and evaluation of a Sound Effects Recognition Test as part of the pediatric audiological evaluation. Such a test may be the only available standardized measure of auditory discrimination in certain children with very limited verbal abilities. The test is comprised of 3 equivalent sets, each containing 10 familiar environmental sounds. Results for normal-hearing pre-schoolers are presented with suggestions for clinical application of the test with hearing-impaired patients.

Auditory Perception↗
PubMedDate not supplied

Language delay in infants associated with middle ear disease and mild, fluctuating hearing impairment.

We report on a study of the relationship between early persistent middle ear disease and early language learning for 35 infants. Three independent measurements were used to evaluate hearing sensitivity and the status of the middle ear. Language development was assessed using two standardized measurements for both comprehension and expression. The otitis-prone group had a 71.5% incidence of language delay with 42.9% delayed greater than 6 months. For the normal group 21.4% had language delay, with one child having delay greater than 6 months. The feasibility of including language screening for at-risk infants is discussed.

Acoustic Impedance Tests↗
PubMedDate not supplied

Brainstem conduction abnormalities in spasmodic dysphonia.

Twelve spasmodic dysphonia patients were evaluated by three different auditory brainstem response parameters; 75% were abnormal. Three of the 12 had prolonged wave I-V interpeak latency. Seven had pathologic wave V latency shifts at a high stimulus rate. Amplitude ratios were normal for all subjects. The authors hypothesize that spasmodic dysphonia is a disorder of variable cranial nerve symptom presentations, and offer several possible models to account for its sporadic representation in the nervous system.

Adult↗
PubMedDate not supplied

Auditory brainstem response with high stimulus rates in normal and patient populations.

Normative data were collected on 48 subjects to determine the effects of increasing stimulus rates on the auditory brainstem response. These subjects were then compared to 221 patients referred for otoneurologic evaluation. The 90 patients with impaired auditory sensitivity demonstrated significantly less wave V latency shift than either the 131 patients with normal auditory sensitivity or the normal subjects. The incidence of abnormal wave V latency shift was 12% in the patients with normal auditory sensitivity and 8% in the patients with impaired auditory sensitivity. The high stimulus rate was often the only ABR parameter indicative of brainstem involvement in patients with documented CNS pathology. The authors conclude that a high stimulus rate contributes to the diagnosis of brainstem pathology often enough to warrant its routine use.

Adult↗