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Biomedical subjects

T Fiore

Publications and source records attributed to T Fiore.

At least 55 records · Page 3Linked to original sources

[Diagnostic usefulness of BAEPs. A clinical case].

We report the clinical case of a patient operated for a right extracerebral haematoma. In the immediate post-operative period, although no clinical signs were present, a BAEP examination (showing the lack of the V) warned of a pathological condition which was ascertained by CT. A second haematoma was observed, contralateral to the first, and immediately removed. In this case, therapy was based on the neuroelectrophysiological findings.

Adult↗

[The treatment of the patient undergoing a thoracotomy after pneumonectomy. Our experience in 2 clinical cases].

The authors report personal experience in two patients undergoing thoracotomy after previous pneumonectomy. They examine the risks and the complications of such surgical procedure (right ventricular failure, respiratory failure). Management consists of restriction of liquid infusions, digitalis administration, use of drugs that have little effect on haemodynamics, epidural analgesia by morphine.

Anesthesia, Endotracheal↗

[Difference between arterial pressure in clino- and orthostatism. A method for evaluating preparation for pheochromocytoma intervention].

Four patients with pheochromocytoma underwent pre-surgical treatment with phenoxybenzamine and volemic expansion. The postural hypotension was evaluated by daily monitoring of the arterial pressure and heart rate in clino orthostatism. The patients underwent surgery and hemodynamic monitoring by Swan-Ganz catheter when postural hypotension was at the lowest level. Hemodynamic data were: elevated cardiac output, normal systemic vascular resistance and filling pressure. These results confirm that the orthostatic hypotension reduction is a valid indication to evaluate the effectiveness of the treatment period with phenoxybenzamine and volemic expansion.

Adolescent↗

Effects of acute intrathoracic pressure changes on left ventricular geometry and filling.

Acute changes in intrathoracic pressure (ITP) affect left ventricular (LV) function. It has been suggested that this functional impairment could be the result of an alteration in LV filling caused by a reduction in LV compliance induced by the rearrangement of biventricular geometry that occurs under these conditions. Therefore, to evaluate the effects of an acute increase or decrease in ITP on LV geometry and filling, we used two-dimensional and Doppler echocardiography to study 25 normal volunteers both during the Müller maneuver (acute decrease in ITP induced by a forced inspiration against a closed airway) and during continuous positive airway pressure breathing. During both maneuvers LV geometry was altered as demonstrated by the significant increase in the normalized curvature radius of the interventricular septum and the unchanged curvature radius of the LV free wall. LV filling was altered during both maneuvers as demonstrated by significant decreases in early peak flow velocity, early-to-late peak flow velocity ratio, and early deceleration rate. Thus, during maneuvers that acutely decrease or increase ITP, alterations in LV geometry occur. These acute distortions of LV geometry may be one of the mechanisms responsible for alterations in LV filling.

Adult↗

Aortic pressure and heart rate patterns during the respiratory cycle in different autonomic conditions in conscious dog.

The relation between respiratory cycle and aortic pressure and heart rate patterns has been studied in the spontaneously breathing conscious dog in four experimental conditions: presence or absence of both vagal and sympathetic activity, presence of activity of only one autonomic branch. Chronic treatment with guanethidine was used to block adrenergic system, while acute, reversible blockade of activity in the cervical vagus was obtained by cooling the nerve. Vagal block was performed before and after guanethidine. In absence of vagal activity, aortic pressure decreased during inspiration and increased during expiration. This pattern was reversed by vagal activity, while it was enhanced by sympathetic activity. The integrative effects of the two branches are responsible for the classic "pulsus paradoxus". The comparison of the four experimental conditions is compatible with the hypothesis that variations of left ventricular preload play the major role in the regulation of ventricular output during respiratory cycle, while the relation between left ventricular output and aortic pressure is largely dependent on autonomic activity.

Animals↗