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Biomedical subjects

T Franken

Publications and source records attributed to T Franken.

49 records · Page 3Linked to original sources

[Radiological observations on bone changes in women after bilateral ovariectomy with and without oestrogen prophylaxis (author's transl)].

A retrospective study was carried out on 69 women who had hysterectomies and bilateral ovariectomies carried out during puberty for non-malignant disease. The effect of oestrogen prophylaxis on bones was studied by various radiological methods (1. Miminal combined cortex thickness in the proximal radius according to Meema; 2. Biconcavity index according to Nordin; 3. Osteoporosis stage in the lumbar spine according to Saville; 4. The Singh index in the proximal femur and 5. Absorption coefficient and relative cortical thickness of the phalanges). It was found the the hormone-treated group (33 cases) showed significantly greater bone density than the control group (36 cases). It is therefore suggested that women undergoing ovariectomy before the menopause, or those with low bone density at the natural menopause, should be treated by long-term oestrogen therapy, provided there are no specific contraindications.

Absorptiometry, Photon↗

[Supravalvular aortic stenosis: Congenital and acquired changes in the ascending aorta near the valve (author's transl)].

Three patients with supravalvular aortic stenosis are described. One was a typical, sporadic-type supravalvular aortic stenosis, another a predominant aortic valve stenosis as part a complex heart lesion and the third inflammatory shrinking of the anulus fibrosus with an inflammatory aortic valve stenosis. The means of diagnosis are discussed. Angiocardiography and aortography are essential in order to demonstrate the pathology, haemodynamics, relation to the coronary arteries and the sinus of Valsalva, and in order to show other abnormalities. The aetiology and pathogenesis of various types of supravalvular aortic stenosis are discussed.

Adult↗

[Aneurysms of the sinus of Valsalva (author's transl)].

Twenty-seven patients in whom a diagnosis of sinus of Valsalva aneurysm had been made during life were re-examined and the results have been evaluated. The clinical symptoms are not diagnostic. Routine radiological examination may also fail to show any significant findings. Large sinus of Valsalva aneurysms may show an atypical prominence of the right upper heart border, and in leutic aneurysms there may be fine calcification of the aortic wall. A definitive diagnosis can be made only by thoracic aortography. Five patients had a congenital saccular aneurysm connected with a sinus of Valsalva. Three patients had acquired aneurysms of which two were leutic and one developed shortly after rheumatic fever. A diffuse aneurysms of the sinus of valsalva was found in fourteen patients with Marfan's syndrome. The radiological appearances are demonstrated. Indications for surgery are discussed; the indications must be considered for each situation separately.

Adult↗

[Xerotomography of the trachea, bronchi and lungs (author's transl)].

The technical principles and the advantages of tomography with the xeroradiographic procedure were presented. The advantages of xerotomography over against film radiography are the simpler exposure procedure, the high degree of picture clarity, the wide range and the additional possibilities for information connected with it. These advantages were illustrated by a few examples. The disadvantage of this method is the high radiation exposure for the patient. For this reason, stricter indications must be required for this examination.

Bronchography↗

[Xeroradiographic field controls on a telecobalt unit in the thoracic, abdominal and pelvic region and in the extremities].

After having modified the method of direct field control by the telecobalt unit for the cranial region and the neck, it has been possible to effect these controls for the thoracic, abdominal, and pelvic region, too. If two sources of radiation are used, it is decisive to cover with lead the zones of half-shadow on the field limits. The technology of direct field control and the advantages for planning and control of the radiation therapy are described.

Abdomen↗

[Mendelson's syndrome (author's transl)].

It is reported on 10 patients with the features of Mendelson's syndrome; 4 patients died. Diagnosis, therapy, course and prognosis of this severe complication following aspiration of gastric hydrochloric acid are discussed.

Adolescent↗

Alteration of the rabbit aorta following feeding of cholesterol diet in combination with sheathing of aortic segments by polyethylen tubes.

Nutritional disturbance and blockage of drainage of the vascular wall which were considered to play an impoetant role in the pathogenesis of arteriosclerosis were experimentally produced by aortic sheathing previously (Huth et al., 1974). Alteration of the rabbit aorta following feeding of cholesterol diet in combination with sheathing of aortic segments by polyethylen tubes is reported in this paper. The results were as follows: 1. When rabbtis were fed a cholesterol diet, atherosclerotic lesions formed in the intima of the aorta. 2. When rabbits were fed a cholesterol diet with simultaneous aortic sheathing, aortic atherosclerosis was also produced within the sheathed segments. 3. When rabbits were fed a cholesterol diet after formation of intimal thickenings within the sheathed segments, lipid deposition was scarce within these segments. The results suggest that among the pathogenetic factors of atherosclerosis a disturbance of vascular nutrition and a blockage of vascular drainage may be of greater importance than hypercholesterolemia.

Animals↗

[Radiographs of the thorax in acute myocardial infarction].

Radiographs of the thorax were evaluated in 240 patients during the acute phase following a myocardial infarct. Following the acute infarct, 53% of the patients showed some cardiac enlargement, in a quarter this was marked. Congestive lung changes were found in 53% of patient following the infarct, interstitial pulmonary oedema in 22% and intra alveolar oedema in 9%. Patients with marked cardiac enlargement and those with congestive lung changes showed a bad prognosis, particularly if the congestion did not regress rapidly. Even advanced pulmonary congestion and interstitial oedema may be missed by clinical examination. Radiography of the thorax following acute myocardial infarction is of value in treatment and prognosis.

Acute Disease↗

[Xeroradiographic field control in telecobalt therapy of the cranial and ear-nose-throat regions].

The possibility of direct field verification by xeroradiography in Co-60-teletherapy of the head- and ENT-regions is described. By the effect of intensified contours, anatomical details may present themselves sufficiently as to make possible an objective verification of the irradiation. The particular advantages of this method consist in the simple handling and in the acceleration of the therapy preparations as well as in the possibility of documentation of the radiotherapeutic treatment. It has to be examined if the xeroradiographical procedure can be utilized for direct verification of the fields in other regions of the body too.

Aftercare↗

[Radiographic differential diagnosis of tumors of jejunum and ileum (author's transl)].

Tumors of the small intestine form only 1.5-8% of intestinal tumors. After a survey of localization, type of growth and tendency towards degeneration the most important clinical findings are described. The most common sign is high ileus. Barium swallow is recommended which, when all radiologic criteria are taken into account, may even permit identification of the type of tumor. Typical individual tumors are illustrated and described and differential diagnostic data are given. The potential and limits of angiography are discussed.

Adenoma↗