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Biomedical subjects

T Frye

Publications and source records attributed to T Frye.

5 recordsLinked to original sources

Clinical significance of cervicomedullary deformity in Chiari II malformation.

OBJECTIVE: The purpose of this study was to determine if there is a difference in the caudal extent of brain stem herniation and the degree of cervicomedullary deformity between symptomatic and asymptomatic Chiari II patients. METHODS: Magnetic resonance imaging and the clinical presentation of 14 symptomatic and 59 asymptomatic patients were analyzed. The level of the cervicomedullary deformity below the foramen magnum was measured in both groups. The level of the deformity was identified by the cervical vertebral body or disc space level. RESULTS AND CONCLUSION: Review of our results shows no obvious relationship between the level of cervicomedullary deformity and the presenting symptoms or the outcome after surgical decompression. We conclude that the level of herniation and the cervicomedullary deformity is not a reliable marker to determine which patients may become symptomatic and require decompression or to determine prognosis.

Arnold-Chiari Malformation↗

Two acute pediatric abdominal catastrophes from strangulated left paraduodenal hernias.

We present two cases of catastrophic intestinal obstruction from to strangulation of a left paraduodenal hernia (PDH). PDH is the most common internal hernia. Early diagnosis and treatment are essential because of the high morbidity and mortality associated with strangulation. Early involvement of the surgical team without an overly extensive evaluation in the emergency department is important if this diagnostic suspicion exists. PDH should also be considered when there is a history of chronic, intermittent abdominal pain of unclear cause. To our knowledge, these cases are the first described cases of sudden demise within a few hours of onset of symptoms of a left PDH.

Abdomen, Acute↗

Octave waveband analysis to determine sound frequencies and intensities produced by nebulizers and humidifiers used with hoods.

BACKGROUND: health-care practitioners should be aware of how their equipment and practices can increase the patient's risk for noise-induced hearing loss. PURPOSE: We conducted this study to determine the type of noise produced by humidifiers and nebulizers used with hoods in the neonatal intensive care unit (NICU). We performed octave waveband analysis to determine sound intensities and frequencies because degree of hearing loss from noise exposure is related to the intensity of sound, frequency of sound and duration of exposure. METHODS: We studies 4 simple humidifiers, 3 heated humidifiers, and 4 nebulizers. Sound levels were measured at various frequencies, flows, and water levels using Peace and Shiley oxygen hoods. RESULTS: The findings show that sound levels were significantly louder (p.0.001) for nebulizers compared to humidifiers. Aquapak nebulizers pose the greatest risk for hearing loss because they produce sound at the highest frequencies and volumes. The peak sound levels of humidifiers not only were significantly lower but also occurred at the lowest sound frequencies, which are the least damaging to hearing. Sound levels were generally higher across sound frequencies at higher flows and with the Peace Hood. CONCLUSION: We conclude that heated humidifiers produce lowest sound intensities at the lowest sound frequencies and, consequently, are most appropriate for use in the NICU.

Environmental Exposure↗

Achondroplasia-hypochondroplasia complex.

We report on a 14-year-old girl with the achondroplasia-hypochondroplasia complex. This patient has been reported previously [McKusick et al, 1973], and we offer an update on her condition. The patient has clinical features different from both achondroplasia and hypochondroplasia and is mentally retarded. Radiological changes, which have occurred over 14 years, are included.

Achondroplasia↗

Previously undescribed syndrome of craniofacial, hand anomalies, and sensorineural deafness.

We describe in a mother and her infant daughter a previously unreported syndrome of unusual craniofacial, hand, and digital anomalies. Both mother and child have a flat facial profile, hypertelorism, hypoplastic nose with slit-like nares, and a sensorineural hearing loss. Common radiographic manifestations include small maxilla, absent or small nasal bones, and ulnar deviation of the hands. This is either an autosomal dominant or X-linked trait.

Abnormalities, Multiple↗